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D Espinós Pérez

Publications and source records attributed to D Espinós Pérez.

At least 19 recordsLinked to original sources
PubMed2004

[Neurocysticercosis: report of three cases and recommendations of treatment].

Neurocysticercosis is a pathology that we are finding nowadays over the immigrant population. It is produced by the Taenia solium parasite when it encyst into the central nervous system. The most frequent clinic is the focal crisis though it can come up as a general crisis; hydrocephalus, intracranial hypertension and even encephalitis can also happen. Its diagnosis is mainly based on imaging methods. The treatment is still controversial and must be individualized. The indication of antiparasitic drugs like albendazole and praziquantel has to be considered depending on the viability of the parasite, the number of cysts and their localization. If a cyst grows up the treatment is always recommended. In the case of an intracranial hypertension arises, this has to be treated before initiating any other action against the parasitic disease. Antiepileptic drugs are necessary to treat the symptoms. In some cases it is also recommended the use of steroids before and during the administration of antiparasitic therapy and even independently on their own.

Adult↗
PubMed2003

[Kikuchi's disease: a case report and literature review].

Kikuchi-Fujimoto disease, also known as hystiocytic necrotizing lymphadenitis, is an unusual entity which affects predominantely young Asiatic females, although its distribution is world-wide. Cardinal symptoms are fever and adenopathy, generally cervical, although generalized and extraganglionar cases have been described. Considered a self-limiting disease, it has to be differentiated by pathologic analysis from other less-benign disorders such as lymphoma or histiocytoma, which bear worse prognosis and may require specific treatment. Although the origin of this disease is unknown, a viral origin is postulated and the immune system is involved Kikuchi disease has been associated to other entities such as subcutaneous lupus erythematosus, Hashimoto thyroiditis, etc... requiring that patients be followed immunologically alter diagnosis of this disease. We present a case of Kikuchi disease associated with subacute lymphocytic thyroiditis.

Adult↗
PubMed2003

[Free radicals and cytotoxicity of ethanol over human leucocytes in peripheral blood].

INTRODUCTION: The ingestion of alcohol produces oxydative stress generating free radicals of oxygen and ethanol. These free radicals have a molecular reactive ability and, therefore, they play an important role in the production of the injury which appears in the liver and in other organs and tissues. We have done an "in vitro" study where we analyse the oxydative status at rest and the respiratory explosion produced by ethanol at final concentrations of 50 and 25 mM and by the phagocytosis of a previously opsonized concentrate of bacteria (E.coli) in human leucocytes taken from peripheral blood of six healthy persons. METHOD: We have used 1.2.3. dihydrorhodamine (non-fluorescent) as the oxydative marker because it is transformed in rhodamine (fluorescent), which is quantitatively studied by Flow Cytometry. RESULTS: The peak of oxydative stress is reached with the bacteria in the phagocytes (monocytes 50% and granulocytes 90%) and it has a significant difference with the control group. By adding ethanol at 50 mM we have seen an statistic significant difference in oxydative stress in the cells of all three types (lymphocytes 9.19%, monocytes 32% and granulocytes 36%). With a concentration of 25 mM of ethanol the oxydative stress is increased but without a significant difference (lymphocytes 2.39%, monocytes 9.22% and granulocytes 4.46%). We have also seen toxic cellular effect which reaches the 40.75% of cells with ethanol at 50 mM, the 10.7% with ethanol at 25 mM and the 5.65% with bacteria. CONCLUSION: The oxydative stress caused by the production of oxygen and ethanol free radicals in the leucocytes, and the proved cytotoxic effect of ethanol may play an important role over the qualitative and the quantitative leucocyte disorder on different organs and tissues of the alcoholic patient.

Ethanol↗
PubMed2001

[The future medicine].

The Medicina of XXI century, due to the advances of technology, molecular biology and genetics will be scientifically encouraging but at the same time revolutionary. Medicine dangerously can be too technological and less humane. Society must know that medicine will be much more expensive. Medicine of XXI century will require to be much more preventive and enlarge the background of bioethics. The XXI century society is in danger to consider the physician only as a dispensing health technician, breaking the important patient physician relation ship.

Bioethical Issues↗