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Biomedical subjects

D Esteve

Publications and source records attributed to D Esteve.

At least 19 recordsLinked to original sources

Superconducting atomic contacts under microwave irradiation.

We have measured the effect of microwave irradiation on the dc current-voltage characteristics of superconducting atomic contacts. The interaction of the external field with the ac supercurrents leads to replicas of the supercurrent peak, the well-known Shapiro resonances. The observation of supplementary fractional resonances for contacts containing highly transmitting conduction channels reveals their nonsinusoidal current-phase relation. The resonances sit on a background current which is itself deeply modified, as a result of photon-assisted multiple Andreev reflections. The results provide firm support for the full quantum theory of transport between two superconductors based on the concept of Andreev bound states.

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Effect of magnetic impurities on energy exchange between electrons.

In order to probe quantitatively the effect of Kondo impurities on energy exchange between electrons in metals, we have compared measurements on two silver wires with dilute magnetic impurities (manganese) introduced in one of them. The measurement of the temperature dependence of the electron phase coherence time on the wires provides an independent determination of the impurity concentration. Quantitative agreement on the energy exchange rate is found with a theory by Göppert et al. that accounts for Kondo scattering of electrons on spin-1/2 impurities.

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Zener enhancement of quantum tunneling in a two-level superconducting circuit.

We have investigated the macroscopic quantum tunneling (MQT) of the phase across a Josephson junction embedded in a superconducting circuit. This system is equivalent to a spin 1/2 particle in a potential energy well. The MQT escape rate of such a particle was recently predicted to be strongly modified when a crossing of its inner Zeeman levels occurs while tunneling. In this regime, we observe a significant enhancement of the MQT rate and compare it to theory.

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Direct observation of dynamical bifurcation between two driven oscillation states of a Josephson junction.

We performed a novel phase-sensitive microwave reflection experiment which directly probes the dynamics of the Josephson plasma resonance in both the linear and the nonlinear regime. When the junction was driven below the plasma frequency into the nonlinear regime, we observed for the first time the transition between two different dynamical states predicted for nonlinear systems. In our experiment, this transition appears as an abrupt change in the reflected signal phase at a critical excitation power. This controlled dynamical switching can form the basis of a sensitive amplifier, in particular, for the readout of superconducting qubits.

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NMR-like control of a quantum bit superconducting circuit.

Coherent superpositions of quantum states have already been demonstrated in different superconducting circuits based on Josephson junctions. These circuits are now considered for implementing quantum bits. We report on experiments in which the state of a qubit circuit, the quantronium, is efficiently manipulated using methods inspired from nuclear magnetic resonance (NMR): multipulse sequences are used to perform arbitrary operations, to improve their accuracy, and to fight decoherence.

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Microtechnology applications for medical instrumentation.

The recent progresses in microtechnologies open new possibilities in terms of design, cost reductions, improve performances and, moreover, open new fields of applications in surgical instrumentation. Microtechnology techniques will lead to reconsider the design of medical instrumentation. Surgical tools should not be thought as mechanical systems but as surgical components ("surgical chips") designed with micro-technologies and including microsensors/microactuactors.

Biomedical Technology↗

Density of states in a superconductor carrying a supercurrent.

We have measured the tunneling density of states (DOS) in a superconductor carrying a supercurrent or exposed to an external magnetic field. The pair correlations are weakened by the supercurrent, leading to a modification of the DOS and to a reduction of the gap. As predicted by the theory of superconductivity in diffusive metals, we find that this effect is similar to that of an external magnetic field.

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Magnetic-field-dependent quasiparticle energy relaxation in mesoscopic wires.

In order to find out if magnetic impurities can mediate interactions between quasiparticles in metals, we have measured the effect of a magnetic field B on the energy distribution function f(E) of quasiparticles in two silver wires driven out of equilibrium by a bias voltage U. In a sample showing sharp distributions at B=0, no magnetic field effect is found, whereas, in the other sample, rounded distributions at low magnetic field get sharper as B is increased, with a characteristic field proportional to U. Comparison is made with recent calculations of the effect of magnetic-impurities-mediated interactions taking into account Kondo physics.

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Manipulating the quantum state of an electrical circuit.

We have designed and operated a superconducting tunnel junction circuit that behaves as a two-level atom: the "quantronium." An arbitrary evolution of its quantum state can be programmed with a series of microwave pulses, and a projective measurement of the state can be performed by a pulsed readout subcircuit. The measured quality factor of quantum coherence Qphi approximately 25,000 is sufficiently high that a solid-state quantum processor based on this type of circuit can be envisioned.

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Direct measurement of the Josephson supercurrent in an ultrasmall Josephson junction.

We have measured the supercurrent flowing through a nonhysteretic, ultrasmall, voltage-biased Josephson junction. In contrast with experiments performed so far on hysteretic Josephson junctions, we find a supercurrent peak whose maximum I(s max) increases as the temperature T decreases. The asymptotic T = 0 value of I(s max) agrees with the junction Ambegaokar-Baratoff critical current, as predicted by theory.

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Direct link between Coulomb blockade and shot noise in a quantum-coherent structure.

We analyze the current-voltage characteristic of a quantum conduction channel coupled to an electromagnetic environment with arbitrary frequency-dependent impedance. In the weak blockade regime the correction to the Ohmic behavior is directly related to the channel current fluctuations, vanishing at perfect transmission in the same way as shot noise. This relation can be generalized to describe the environmental Coulomb blockade in a generic mesoscopic conductor coupled to an external impedance, as the response of the latter to the current fluctuations in the former.

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Multiple-charge-quanta shot noise in superconducting atomic contacts.

We have measured shot noise in aluminum atomic point contacts containing a small number of conduction channels of known transmissions. In the normal state, we find that the noise power is reduced from its Poissonian value and reaches the partition limit, as calculated from the transmissions. In the superconducting state, the noise reveals the large effective charge associated with each elementary transfer process, in excellent agreement with the predictions of the quantum theory of multiple Andreev reflections.

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Electrodynamic dip in the local density of states of a metallic wire.

We have measured the differential conductance of a tunnel junction between a thin metallic wire and a thick ground plane, as a function of the applied voltage. We find that near zero voltage, the differential conductance exhibits a dip, which scales as 1/square root of [V] down to voltages V approximately 10k(B)T/e. The precise voltage and temperature dependence of the differential conductance is accounted for by the effect on the tunneling density of states of the macroscopic electrodynamics contribution to electron-electron interaction, and not by the short-ranged screened-Coulomb repulsion at microscopic scales.

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Multiple Andreev reflections revealed by the energy distribution of quasiparticles.

We have performed the tunnel spectroscopy of the energy distribution function of quasiparticles in 5-microm-long silver wires connected to superconducting reservoirs biased at different potentials. The distribution function f(E) presents several steps, which are manifestations of multiple Andreev reflections at the NS interfaces. The rounding of the steps is well explained by electron-electron interactions.

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Proximity effect and multiple Andreev reflections in gold atomic contacts.

We investigate the electronic transport properties of gold point contacts with superconducting aluminum leads. The modifications induced by the proximity effect in the quasiparticle density of states at the contact region are measured by tunnel spectroscopy. The theory of transport through multiple Andreev reflections is extended to incorporate these effects and used to determine the number and transmission coefficients of the conduction channels in the contact regime. We find that the smallest contacts, formed by one gold atom between the electrodes, contribute one single channel to the transport with variable transmission T between 0.1 and 1.

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Preliminary study of the deposition of aerosol in the maxillary sinuses using a plastinated model.

In spite of the widespread use of aerosols in respiratory diseases, very few studies have been performed in the field of ear, nose, and throat (ENT) disorders. The conditions for penetration of aerosols inside the sinus cavities are thus still not understood fully. The aim of this study was to investigate the penetration of aerosols inside maxillary sinuses in vitro, using plastinated models. Three plastinated specimens of the nose and sinuses were made from three different corpses. These specimens were validated by CT scans and were used to study deposition of aerosol in the maxillary sinuses. We performed scintigraphic images of the models in above, face, and profile views using a technetium (99mTc)-labelled solution to show aerosol deposition. We also counted the radioactivity deposited on gauze compresses placed inside the maxillary sinuses. In addition, we constructed a measuring unit with miniature humidity sensors placed inside the sinuses. We recorded the changes in relative humidity observed during nebulization. Results from these studies showed that scintigraphic images of the specimen, whatever the incidence of the views, were not accurate enough to differentiate the aerosol deposition in the maxillary sinuses from that in the nasal cavity. Using indirect counting on gauze compresses made possible the quantification of local aerosol deposition, and we found that aerosols entered into the sinuses. This confirmed that aerosols could reach the middle meatus, which is the main area for sinusitis disorders. The increased activity compared to background varied from 17 to 127%. The humidity sensors recorded changes in relative humidity during the nebulization. These humidity changes fitted a nonlinear model represented by the equation: y = b0 (1 - e(-b1t)), where b0 is the plateau and b1 is the speed to reach the plateau. These techniques may be useful in the future for in vitro characterization of aerosol penetration into the maxillary sinuses.

Aerosols↗

Supercurrent in atomic point contacts and andreev states

We have measured the supercurrent in aluminum atomic point contacts containing a small number of well characterized conduction channels. For most contacts, the measured supercurrent is adequately described by the opposite contributions of two thermally populated Andreev bound states per conduction channel. However, for contacts containing an almost perfectly transmitted channel 0.9</=tau</=1 the measured supercurrent is higher than expected, a fact that we attribute to nonadiabatic transitions between bound states.

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