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Biomedical subjects

D F Marcus

Publications and source records attributed to D F Marcus.

32 records · Page 2Linked to original sources

Sarcoid granuloma of the choroid.

Two patients were found to have macular choroidal granulomas associated with systemic sarcoidosis. This unusual fundus picture was documented by serial fundus photography and fluorescein angiography. Both patients had a similar clinical picture of decreased vision, chorioretinal granulomas, and overlying neurosensory detachments. Staining of the inflammatory mass with fluorescein and leakage of dye into the neurosensory space was typical. Lymph node biopsies were performed to substantiate the diagnosis. Both patients responded promptly to systemic corticosteroid therapy with dramatic improvement in visual acuity and resolution of the choroidal lesions.

Adrenal Cortex Hormones↗

Nitrous oxide levels during retinal cryosurgery.

Nitrous oxide levels were monitored before, during, and after retinal cryotherapy. These units produced an average elevation of the nitrous oxide concentration in the operating room to the level of 963 ppm. Nitrous oxide levels in a control operating room using general endotracheal anesthesia with nitrous oxide ranged from 75 to 200 ppm. Nitrous oxide has been reported to be associated with various teratogenic effects in experimental animals and may be associated with other human ailments. The use of a scavenger system specifically designed to handle the exhaust from ophthalmic nitrous oxide units can reduce the nitrous oxide concentration by 50% or more and is, therefore, recommended.

Cryosurgery↗

Intraretinal macrocysts in retinal detachment.

Seven cases of retinal detachment were associated with ophthalmoscopically visible macrocysts. These cysts were associated with long-standing retinal detachment, particularly of the traumatic type with retinal dialysis. They arose from the outer plexiform layer of the retina. In four cases, the macrocyst extended to the ora serrata. Most macrocysts require no specific attention during retinal detachment repair. If the cyst prevents closure of the primary retinal break, we advocate its surgical drainage. Four cases in the present series required surgical collapse of the macrocyst.

Adolescent↗

Central retinal artery occlusion.

Central retinal artery occlusion is characterized by sudden, painless visual loss due to blockage of retinal blood flow. It has been reported in all age groups including children but is most frequent in the sixth decade. Both thrombosis and embolism have been suggested as possible mechanisms. The emergency treatment includes intravenous acetazolamide, digital ocular massage, and inhalation of 5% carbon dioxide -- 95% oxygen for ten minutes. Following emergency treatment, immediate ophthalmologic referral and consultation is required. Comprehensive medical evaluation should be initiated to exclude systemic vascular disease.

Aged↗

Anterior segment necrosis following treatment of central retinal artery occlusion: a clinicopathologic case report.

A 45-year-old man with an internal carotid artery occlusion, cerebral hemispheric infarction, and an ipsilateral central retinal artery occlusion developed anterior segment necrosis after retrobulbar injection of lidocaine hydrochloride (Xylocaine) for treatment of an occlusion of the central retinal artery. Multiple embolic plaques in the retinal circulation with occlusion of the posterior ciliary arteries were found. The clinical and postmortem histopathologic findings are presented.

Arterial Occlusive Diseases↗

Argon laser photocoagulation treatment of diabetic cystoid maculopathy.

Forty-one patients with diabetic cystoid macular edema were treated with argon laser photocoagulation and followed for a mean period of 22 months. The fellow eye was held as control. In the treated group (33 eyes), 6 had an improvement in visual acuity (greater than 2 lines), 19 had visual acuity which remained the same (+/- 1 line), and 8 had a decrease in visual acuity (more than 2 lines). In the control group (33 eyes untreated), 18 had a visual acuity which remained the same, one had an improvement in visual acuity (greater than 2 lines) and 14 had a decrease (greater than 2 lines) in visual acuity. The control eyes of 14 patients were treated because of significant reduction in visual acuity. Although the general tendency toward stabilization in the treated group and toward deterioration in the untreated group was definitely observed, statistical evaluation did not show a significant difference between the 2 groups. Occasionally, patients with cystoid in the control eye cleared spontaneously without treatment.

Adult↗

Radial retinotomy in the macula.

Radial retinotomy is an operative procedure usually performed in the peripheral or equatorial retina. To facilitate retinal attachment, the authors used intraocular scissors to perform radial retinotomy in the macula of two patients during vitrectomy surgery. In the first patient, a retinal detachment complicated by periretinal proliferation and macula hole formation was successfully reoperated with the aid of three radial cuts in the retina at the edges of the macular hole. In the second patient, an intraoperative retinal tear in the macula during diabetic vitrectomy was also successfully repaired with the aid of radial retinotomy. In both patients, retinotomy in the macula was required because epiretinal membranes, which could not be easily delaminated, were hindering retinal reattachment.

Adult↗