Infective discitis due to Staphylococcus lugdunensis--a case of missed opportunity.
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Biomedical subjects
Publications and source records attributed to D F Sallomi.
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In this review the imaging features of a range of parotid lesions are presented and the roles of ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) in the assessment of parotid disease are discussed.
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Scintimammography has a high specificity and sensitivity for the detection of primary and metastatic breast carcinoma and in the evaluation of the postoperative breast. This review highlights the spectrum of pathological features as well as the normal postoperative and postreconstruction changes and the variable normal appearances that may be encountered with this technique.
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Ultrasound examination is the primary imaging investigation used in initial evaluation of the symptomatic testis. In this review the ultrasound appearances of a range of testicular lesions are demonstrated. Particular attention is given to the subject of testicular microlithiasis and its link with germ-cell neoplasia, and also to the sonographic features of epidermoid cysts that may allow testis-sparing surgery.
Liver biopsy is still most commonly done via the percutaneous route; however, increasingly, transvascular venous liver biopsy has been used in patients with bleeding disorders. Although the jugular route is now generally favoured, a transfemoral route can be a useful alternative technique when the jugular route is not available. We describe the transfemoral technique and outline a number of commonly encountered problems and complications and suggested methods of addressing them.
Over the past decade, increasing use of chemo-embolization with chemotherapeutic agents emulsified in oil has been made in the treatment of both primary and metastatic liver tumours. These lesions are often not amenable to surgical resection and are not responsive to systemic chemotherapy. Chemo-embolization provides an additional therapeutic option which, in some instances, can provide significant benefit. This pictorial review discusses the technique of chemo-embolization, as well as aspects of patient selection, complications, and tumour response.
OBJECTIVE: To assess a three-dimensional computed tomography (3DCT) technique for measurement of acetabular coverage in adults. DESIGN: We used 3DCT to define the geometric centre of the femoral head and to measure centre-edge angles (CEAs) at 10 degrees rotational increments around the acetabular rim. The means, ranges, standard deviations and 95% confidence intervals for the CEAs at the various rotational increments were determined. Inter- and intra-observer variability was measured. The normal values are compared with two example cases of acetabular dysplasia. PATIENTS: The normal hips of 15 subjects aged 1949 years (mean 34.2 years) were measured. RESULTS: The 3DCT measurements are reproducible (mean difference interobserver, 1.7 degrees - 7.9 degrees; mean difference intra-observer, 0.6 degrees-6.9 degrees). Mean normal CEA at the lateral rim was 33 degrees with a 95% confidence interval of 23 degrees - 43 degrees. Mean normal CEAs at 10 rotational increments from anterior to posterior rim were determined, and graphed as a 'normal curve'. CONCLUSION: This new 3DCT method of assessing acetabular dysplasia is simple, reproducible, and applicable to diagnosis, quantification and surgical planning for adult acetabular dysplasia patients.
Giant cell tumour of bone is a relatively common neoplasm with limited potential for metastatic spread. These tumours usually occur at the ends of bones with their epicentre in the epiphysis. This essay will review the various common and some of the less frequently encountered manifestations of giant cell tumours at multiple different sites, as well as postoperative recurrence. Different imaging modalities including plain film, tomography, computed tomography and magnetic resonance imaging are shown.
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Acute bilateral renal cortical necrosis is a relatively rare cause of acute renal failure accounting for only 2% of cases in the Western World. The pathophysiology of this condition is complex, but ultimately leads to the destruction of the renal cortex with sparing of the renal medulla. A definitive diagnosis is based on renal histology. In this report we describe a patient in whom this diagnosis was made using contrast-enhanced computed tomography as renal biopsy was contraindicated.
Seventeen severely anaemic and transfusion-dependent haemodialysis patients with a haemoglobin less than 7 g/dl were treated with recombinant human erythropoietin (r-Hu-EPO). Aluminium toxicity was diagnosed by a positive desferrioxamine (DFO) test and bone biopsy. Seven out of eight patients without aluminium toxicity responded to r-Hu-EPO therapy. Similarly all patients with aluminium toxicity (n = 4) but pre-treated with standard dose of DFO prior to r-Hu-EPO therapy responded but none of the patients with untreated aluminium toxicity (n = 5) responded to r-Hu-EPO therapy. In order to achieve adequate response in these patients, r-Hu-EPO and DFO had to be given in combination. The dose of desferrioxamine used to reverse r-Hu-EPO resistance was less and also used for a short time. We therefore confirm r-Hu-EPO resistance owing to aluminium overload and report its successful and safe reversal with low dose DFO therapy.
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Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in adults. This pictorial essay describes and illustrates the clinical, pathologic, and radiologic features of MFH. The cross-sectional imaging features on CT and MRI are emphasized in relation to the diagnosis and staging of MFH.