Biomedical subjects

D F Sobel

Publications and source records attributed to D F Sobel.

39 records · Page 3Linked to original sources

PubMedDate not supplied

NMR of the normal and pathologic eye and orbit.

Nuclear magnetic resonance (NMR) images of the eye and orbit were reviewed in a series of 100 normals and in four patients with orbital or ocular pathology. A rich retrobulbar fat content rendered the orbit well suited for NMR imaging. The lens, vitreous, optic nerve, and extraocular muscles were well visualized with spin-echo technique. However, NMR spatial resolution was inferior to that of high-resolution computed tomography (CT). NMR was comparable to CT in demonstrating choroidal melanoma and orbital pseudotumor. NMR exhibited a particular sensitivity in displaying tissue contrast for infiltrative orbital fat lesions with a relatively long T1. This initial experience suggests a promising role for NMR in orbital imaging.

Adolescent↗

PubMedDate not supplied

Metrizamide myelography and postmyelographic computed tomography: comparative adequacy in the cervical spine.

Metrizamide myelography and postmyelographic computed tomography (CT) were evaluated for relative efficacy when correlated with operative findings in a series of 30 patients. Fifty-seven levels were operated on in the 30 patients with 27 patients diagnosed as having diffuse cervical stenosis, hyperostotic spondylosis, or herniated nucleus pulposus. Metrizamide myelography and CT metrizamide myelography were equally useful in providing preoperative diagnostic information at 44 of 57 levels. Both radiographic techniques agreed with the degree of canal and neural forman stenosis found operatively at more than 80% of levels. This study indicates that either metrizamide myelography or CT myelography alone is sufficient, and that both should be performed only if one fails to answer the clinical question or if syringomyelia or cord tumors are suspected.

Adult↗

PubMedDate not supplied

Locating the central sulcus: comparison of MR anatomic and magnetoencephalographic functional methods.

PURPOSE: To compare MR anatomic and magnetoencephalographic (MEG) functional methods in locating the central sulcus. METHODS: Eleven healthy subjects and five patients with focal cerebral lesions were studied. The central sulcus was located anatomically with MR by two independent observers using axial vertex and sagittal (midline and lateral) images. Locations via the MEG functional method were based on detecting the somatosensory-evoked magnetic fields elicited by painless tactile stimuli. RESULTS: The axial method yielded the most consistent interrater results, with complete agreement in 76% of sections in both control subjects and patients. The intermethod discordance of the sagittal midline and lateral methods was 32% in control subjects and 33% in patients. The concordance of MR and MEG methods ranged from 55% to 84% in control subjects and 65% to 67% in patients. CONCLUSION: MR anatomic techniques can usually identify the central sulcus, but in the presence of anatomic distortion, the MEG functional method adds significant information.

Adult↗