[Mouse disease due to vesicular stomatitis virus. I. Spread of the virus dependent on the age of the mouse].
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Aging↗
Biomedical subjects
D Falke
Publications and source records attributed to D Falke.
[Mouse disease due to vesicular stomatitis virus. II. Pathology of organ lesions and the involvement of the central and peripheral nervous systems].
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Aging↗
Investigations on the mechanism of induction of the alkaline phosphatase by bromodesoxyuridine in herpes simplex virus transformed cells and the transport of uridine.
Addition of BrdUrd in combination with prednisolone to HSV1-transformed hamster embryo cells induces an alkaline phosphatase (AP). FdURd enhances, dThd reduces the inducing capacity of BrdUrd and prednisolone. Induction is prevented by addition of cycloheximide or of cytosine arabinoside. BrdUrd reduces transport and phosphorylation of exogenously applied labeled Urd, especially the amount of UTP, UDP and Urd-diphosphate sugars. The Lineweaver-Burk-plot of uridine-uptake after addition of BrdUrd reveals the characteristics of the mixed type inhibition (competitive-noncompetitive).
Alkaline Phosphatase↗
Deoxyribonucleases in herpes simplex virus type 1 and 2 infected primary rabbit kidney cells.
In primary rabbit kidney cells infected with herpes simplex virus four different neutral deoxyribonuclease activities can be detected by means of the deoxyribonuclease assay in DNA-containing polyacrylamide gels following their separation by disc-electrophoresis. The method is suitable to follow independently the change in each activity of the different enzymes using only about 5 X 10(5) cells for each assay during the time-course of infection. Under these conditions one enzyme activity is constant, two disappear while the activity of a fourth one present only in infected cells, increases.
Animals↗