Weight gain and longterm complications with atypical antipsychotics.
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Biomedical subjects
Publications and source records attributed to D Farver.
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Rapid improvement of tardive dyskinesia was identified following initiation of olanzapine in an elderly male patient formally treated with chlorpromazine.
Neuroleptic malignant syndrome (NMS) is a potentially fatal idiosyncratic complication of neuroleptic treatment. It was first described in 1968 by Delay and Deniker, and is characterized by hyperthermia, extrapyramidal signs, autonomic dysfunction and altered mentation. They reported that 0.5% to 1.0% of the patients on neuroleptic therapy developed NMS. Several retrospective studies have reported the frequency of NMS between 0.02% to 2.44%. These variations in the incidence of NMS may be due to difference in patient population, awareness and experience of clinicians, prescribing habits, different diagnostic criteria, or methodological differences in survey methods.
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Two cases of acute coalescent mastoiditis with subperiosteal abscess are presented. Cultures from both abscesses resulted in bacteria resistant to commonly prescribed oral antibiotics. Historical perspectives on acute mastoiditis as well as the emergence of multi-drug resistant bacteria will be discussed. Current diagnostic evaluation and effective therapy for acute mastoiditis will also be reviewed.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.