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Biomedical subjects

D Ferhati

Publications and source records attributed to D Ferhati.

11 recordsLinked to original sources
PubMed2004

[Bilateral breast cancer. Incidence and risk factors].

OBJECTIVE: To clarify, thanks to a retrospective study of 24 bilateral breast cancer cases, the frequency, the risk factors and the prognosis of bilateral breast cancers. PATIENTS AND METHOD: Between 1984 and 1999, out of 506 patients treated for unilateral non-metastatic breast cancer at Gynecologic and Obstetric ward, at Maternity Souissi of Rabat, 24 cases of bilateral breast cancers were diagnosed. Our results were compared to those of the literature. RESULTS: The frequency of bilateral breast cancers was 4.7% (24/506). In 87.5% of cases, these were metachronous cancers with a mean interval of 45 months (12-144 months). Patients under 40 at first cancer ran a fivefold superior risk than women more than 40 (P < 0.05). In cases of T3 or T4 tumors, the risk was 10-fold superior to that in smaller ones (P < 0.05). DISCUSSION AND CONCLUSION: Significantly more first metachronous tumors were invasive adenocarcinoma cancers. Histologic type of first and second tumor was the same in all cases. The prognosis depends at once on the first and second cancer staging and the treatment must be done according to the same rules as in the first cancer.

Adenocarcinoma↗
PubMed2002

[Primary malignant melanoma of the cervix].

INTRODUCTION: Primary malignant melanoma of the cervix is an extremely rare histological variety of cervical tumor, with only 54 cases reported. OBSERVATION: A 70 year-old woman consulted for metrorrhagia and pelvic pain. Clinical examination revealed a tumefaction on the anterior labium of the cervix. The anatomo-pathological examination of the biopsy led to diagnosis of a malignant melanoma of the cervix. Despite enlarged Wertheim-type colpohysterectomy associated with pelvic lymphadenectomy, pulmonary metastases developed and the patient died six months later. COMMENT: This is a typical case of malignant melanoma of the cervix. All the authors underline the poor prognosis when visceral metastases occur early, as was the case in our patient.

Aged↗
PubMed2002

[Breast tuberculosis].

Tuberculosis rarely affects the breast. The authors report the case of a 50 years-old woman with breast tuberculosis. The main purpose of this case report is to remind clinicians of the unusual presentations of extrapulmonary tuberculosis that can easily be forgotten. Mammary tuberculosis presents a number of diagnostic pitfalls. Diagnosis is based on identification of the tubercle bacillus in cultures or demonstration of typical histological lesions. Antibacillary drugs are the mainstay of therapy. Surgery is used only is cases that fail to respond to medical treatment and/or involve extensive tissue damage. Although rare, tuberculosis of the breast should be considered as a possible diagnosis, particularly in countries where tuberculosis is endemic.

Breast Diseases↗
PubMed1998

[Malignant schwannoma of the breast. A case report].

Malignant schwannoma is a very rare sarcomatous tumor of unknown etiology. Primary mammary localization is exceptional. Clinically, the tumor manifests as an isolated painless nodule visualized as a benign nodule on standard radiogram. Positive diagnosis is provided by pathology. Treatment is surgical. The risk of local recurrence imposes a radical treatment. We report one case and review the literature, underlining the difficulties encountered in diagnosis and emphasizing the recurrent nature of this tumor after conservative treatment.

Adult↗
PubMed1995

[Complete non-obstetrical uterine inversion].

A rare case of a gynaecologic uterine inversion is reported emphasizing on the exceptional character of the gynecologic uterine inversion and the pathogenic problems which are tackled. Gynaecologic inversion results from a tumor implanted on fundus of the uterus or from the essential atrophy of suspension ligaments of the uterus. Treatment depends on the anatomic type and the stage.

Adult↗
PubMed1995

[Struma ovarii. A case report].

Struma ovarii is a rare ovarian tumor composed entirely or in part of thyroid tissue. Pathogenesis is unclear. Diagnosis rests on the histologic study. A case is reported. Specific features of struma ovarii are discussed based on a review of the literature. The treatment is surgical and the outcome generally favorable.

Female↗
PubMed1993

[Krukenberg's tumors. 9 cases. Review of the literature].

The authors report a series of nine cases of Krukenberg's tumor, operated at the university clinic of obstetric gynecology (Professor Chaoui) during a period from 1977 to 1990. They underline the metastatic character of this tumor, whose primitive lesion is very often digestive. In most cases, the diagnosis is set late by histological study of the operatory piece, showing the revealing character of this tumor. All the authors agree upon the very dark prognostic of this tumor. The only hope of improvement lies in an extraction as soon as possible of the primitive tumor, followed by a radical treatment of the ovarian tumor. The contribution of complementary treatment is questionable; however, adjuvant chemotherapy keeps a positive efficacy, according to certain authors. The authors deplore one death in keeping with a late diagnosis.

Adult↗
PubMed1992

[Malignant non-Hodgkin's lymphoma of primary mammary localization. Two cases].

The authors report two cases of non-hodgkinian malignant lymphoma (NHML) of primitive mammary localization. Surveying the data of world literature, they have tried to trace the main characteristics of this breast cancer. The NHML are met at all ages, of female predominance and whose clinical aspect is summarized in two great tables: a module radiologically benign, isolated, quite limited, or a tumor of inflammatory aspect. Anatomopathological exam and the extension check-up constitute a fundamental step to establish the diagnosis, to confirm the initial localization and evaluate the prognosis which depends on two main factors: anatomical stage and histological type. Chimiotherapy is indicated initially, often related to a conservative surgery (tumorectomy), rarely to a radiotherapy.

Adult↗
PubMed1992

[Hypertrophic tuberculosis of the cervix. Three cases].

Tuberculosis of the cervix of the uterus is a rare form of genital tuberculosis. The epidemiology does not have any particular specific feature; but the macroscopic appearance gives a first impression of a cancer. Only by carrying out a biopsy of the cervix, followed by study of the histology can the problem be solved so that longterm anti-tuberculous treatment can be started. There is rarely any need for surgery, that only in cases resistant to medical treatment. The authors report three cases of tuberculosis of uterine cervix, found in the university clinic of obstetrics and gynaecology I (Professor Chaoui) during the years 1986-90. The incidence of this condition is 8.5% of genital tuberculosis. The outlook is good with full healing if the treatment is carried out properly.

Adult↗