Effect of dietary fiber on intestinal mucosal sodium-potassium-activated ATPase.
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Alkaline Phosphatase↗
Biomedical subjects
D Fleiszer
Publications and source records attributed to D Fleiszer.
Protective effect of dietary fibre against chemically induced bowel tumours in rats.
101 rats were fed one of four diets containing graded amounts of dietary fibre. Subcutaeous dimethylhydrazine (D.M.H.) was given to half the rats in each of the diet groups. Stool mass was found to be directly related to the amount of dietary fibre consumed, and the incidence of D.M.H.-induced colon carcinoma was reduced as dietary fibre increased.
Animal Feed↗
Steroid hormone receptors in dimethylhydrazine-induced rat colonic tumors.
The presence of steroid hormone receptors was investigated in rat colonic tumors, experimentally induced by 1,2-dimethylhydrazine, and in adjacent normal tissues. Estrogen, progesterone, glucocorticoid, and 5-alpha-dihydrotestosterone receptor levels were measured by the dextran charcoal competitive binding assay. Estrogen receptors were present in 25% of tumors, although not in adjacent normal tissue. Higher levels of glucocorticoid binding in tumor versus adjacent normal tissue were demonstrated in 5 out of 8 cases. Progesterone and 5-alpha-dihydrotestosterone levels in tumor versus adjacent normal tissue were not significantly different. The results reflect the possible endocrine dependence of colonic tumors.
1,2-Dimethylhydrazine↗