[Intra-arterial and intravenous chemotherapy in the treatment of hepatic metastases of colorectal origin: review of the literature and preliminary results].
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Aged↗
Biomedical subjects
D Focan-Henrard
Publications and source records attributed to D Focan-Henrard.
Phase II trial with high-dose ifosfamide and mesna given in a 24-h infusion for advanced GI tract cancer.
In all, 26 patients with advanced GI tract cancer (among whom 23 had liver metastases) were treated in a phase II trial with a 24-h infusion of high-dose ifosfamide and mesna (5 g/m2). Two PR, 1 CR and 4 NC were evidenced among 23 patients evaluable for response. The toxicity was significant and mainly expressed in the hair, digestive tract, granulocytes and CNS. One patient died from CNS and kidney toxicities. Only patients with good clinical indices, normal serum albumin and creatinine levels and without pelvic involvement seemed to be candidates to benefit from the treatment.
Adult↗
Levamisole or placebo after effective chemotherapy for remission and survival prolongation in advanced human solid tumors--a double-blind randomized trial.
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Aged↗
Circadian CEA variability: when to sample.
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Carcinoembryonic Antigen↗
[Factors determining the prognosis of rheumatic pelvi-spondylitis].
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Humans↗
Radioimmunoassay of the rheumatoid factors.
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Antigen-Antibody Reactions↗
[Value of the analysis of synovial fluid in rheumatology].
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Antibodies, Antinuclear↗
Cancer-associated alteration of circadian rhythms in carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) in humans.
A circadian rhythm of serum concentrations of two tumor markers (CEA and AFP) was demonstrated in individuals not suffering from cancer. These rhythms exhibited a diurnal peak with a nocturnal dip. They disappeared in cancer groups. However, in some cancer subjects, a circadian activity was still detectable, but with quite different characteristics (time of peak, amplitude) of rhythms when compared to controls. The importance of such findings is discussed with regard to the circadian kinetics of cancer cells, to time scheduled cancer treatments and to the detection of cancer.
Carcinoembryonic Antigen↗