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Biomedical subjects

D Fogel

Publications and source records attributed to D Fogel.

7 recordsLinked to original sources
PubMed2000

Mammography utilization in a skilled nursing facility.

OBJECTIVE: To examine mammography utilization and subsequent clinical decisions in a skilled nursing facility in women aged 75 years and older with no history of breast cancer. METHODS: This study was a retrospective medical chart review of 95 women living in a skilled nursing facility aged 75 years and older who did not have a history of breast cancer. RESULTS: One-hundred seventy-nine mammograms were performed on 95 patients with an average of 1.9 mammograms per patient. Forty-five percent of the women had some evidence of abnormal results requiring further investigation. DISCUSSION: Determining the utility of screening mammography in long-term care populations is essential to the development of appropriate guidelines. Future research should further explore the influence of patient preferences and psychological burden.

Aged↗
PubMed1999

[Alpha-amino adipic aciduria: a rare psychomotor syndrome].

A 3.5-year-old boy with developmental motor retardation, hypotonicity, and severe speech disturbance had alpha-amino adipic acid in his blood and very high levels in his urine. In only 20 cases has this catabolite of lysine and hydroxylysine been found in high concentrations in urine, due to enzymatic block. The clinical features associated with alpha-amino adipic aciduria may include mental retardation, developmental and motor delay, learning difficulties, convulsions, speech problems and ataxia. 3 siblings had milder symptoms of psychomotor delay and intermediate degrees of alpha amino-adipic aciduria, suggesting that the described developmental deficits could be related to this metabolite or its derivatives.

2-Aminoadipic Acid↗
PubMed1983

Comparison between the combination of azlocillin-gentamicin and ampicillin-gentamicin in the treatment of a nursery population.

Newborn, and particularly premature infants are prone to life-threatening infections. The combination of ampicillin-gentamicin (AM-G) has been used extensively in neonatal intensive care units (NICU). Because resistant bacteria emerged, a new drug--an acylureidopenicillin, azlocillin, with a wide antibacterial spectrum--has been developed. A prospective randomized study was performed in order to evaluate the combination of AM-G vs. azlocillin-gentamicin (AZ-G). Thirty neonates received AM-G and 28 received AZ-G. Definite infection was found in 15 AM-G patients and in 10 AZ-G patients. In these patients, the antibiotic regimen was changed in six of the AM-G and in one of the AZ-G patients. In each of the two treatment groups, one very-low-birth-weight baby died due to overwhelming sepsis. In vitro sensitivity to AZ-G was higher than to AM-G, according to azlocillin blood levels obtained. Infants weighting less than 2,350 g had lower clearance and volume of distribution than did infants weighing greater than 2,350 g. The serum half-life was approximately the same in both groups. It appears to be that in the NICU, the combination of AZ-G may be more effective than the AM-G combination.

Ampicillin↗
PubMedDate not supplied

Treatment with bifonazole shampoo for scalp seborrhea in infants and young children.

Thirty-four infants and children were prescribed bifonazole 1% shampoo as a treatment for lesions of scalp seborrheic dermatitis. All but one were cured or showed improvement within a short period. No serious side effects were observed. We conclude that bifonazole 1% shampoo is an effective and safe treatment for lesions of scalp seborrheic dermatitis in infants and young children.

Antifungal Agents↗