Abnormal patterns of cerebrospinal fluid flow and absorption after head injuries; diagnosis by isotope cisternography.
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Biomedical subjects
Publications and source records attributed to D Front.
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A method for a combined air and isotope ventriculography is described. Twenty-nine infants with suspected hydrocephalus were studied. The merit of the combined study is the possibility of obtaining both anatomical and functional information. A very small amount of radioactivity-15 μc-was found to give satisfactory results. Patterns of cerebrospinal fluid flow in communicating and non-communicating hydrocephalus and in cases of porencephalic cyst and complete obstruction of the lateral ventricles are described.
The diagnosis of porencephaly by isotope cisternography is described. In the three cases presented, porencephaly was associated with non-resorptive hydrocephalus. The communicating hydrocephalus caused the isotope to enter the ventricular system and visualize the cyst, and the diagnosis of both disorders was established by RIHSA cisternography. The method is simple and non-traumatic and provides information about abnormalities which air may fail to demonstrate.
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The ejection fraction (EF) of the left ventricle was measured by radionuclide ventriculography in 64 patients during an acute cerebrovascular accident. Sixteen patients (12 with coronary artery disease) died within two weeks of the onset of symptoms and had only one EF measurement. In the remaining 48 patients, the EF was also measured two weeks and three months after the acute event. The ejection fraction of the patient who died soon after the acute stroke (52 +/- 18) was significantly lower than that of the patients who survived (64 +/- 10) (p less than 0.01). Of the patients who survived, 28 without history of coronary disease had an EF of 67 +/- 10 during the acute event. It was significantly higher than that measured after two weeks (60 +/- 10) p less than 0.01). In 10 patients with history of chronic stable angina pectoris, the EF (59 +/- 10) was significantly lower in the first study compared to that measured in the second (69 +/- 10) (p less than 0.02). Ten patients with no evidence of ischemia but with a history of myocardial infarction had a higher EF (61 +/- 11) during the first study as compared to the second (51 +/- 11) (p less than 0.05). In all patients there was no significant difference in the EF measurements between the second and the third study. It is suggested that the EF response of the left ventricle of the heart to the acute cerebrovascular accident is similar to that observed in a stress test.(ABSTRACT TRUNCATED AT 250 WORDS)
Nuclear medicine contributes to the diagnosis and management of extracranial head and neck diseases through the physiological information it provides. In addition to thyroid and parathyroid indications, radionuclide studies, i.e., bone and 67Gallium citrate scans are helpful in diagnosing and treating head and neck malignancies. Positron emission tomography with 18F-fluorodeoxy-glucose evaluates tumor glucose metabolism before and after treatment. Triphase bone scintigraphy enables early detection of osteomyelitis of the skull base, and its management requires 67Gallium-citrate or 111Indium-WBC scintigraphies. Salivary gland scintigraphy is the only functional imaging test of salivary tissue and should be utilized more in the diagnosis of submandibular duct obstruction and in the evaluation of preserved parenchymal function after recurrent infections.
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