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D G Ansel

Publications and source records attributed to D G Ansel.

6 recordsLinked to original sources
PubMed1988

A clinical and pathologic study of chronic sinusitis: the role of the eosinophil.

Evidence exists that the eosinophil plays an important role in mediating injury to bronchial epithelium in chronic asthma. Here, the role of the eosinophil in chronic inflammatory disease of the paranasal sinuses was studied with tissue from patients who underwent surgery for chronic sinusitis. Paranasal tissue from patients with chronic asthma and/or allergic rhinitis was extensively infiltrated with eosinophils. Immunofluorescent studies demonstrated a striking association between the presence of extracellular deposition of major basic protein and damage to sinus mucosa. The histopathology of paranasal respiratory epithelium appeared similar to that described in bronchial asthma. These findings suggest that the eosinophil acts as an effector cell in chronic inflammatory disease of paranasal respiratory epithelium. Thus, sinus disease in patients with asthma may be due to the same mechanisms that cause damage to bronchial epithelium.

Adolescent↗
PubMed1979

Agnogenic myeloid metaplasia with a parotid mass.

Agnogenic myeloid metaplasia, one of the entities in the myeloproliferative syndrome, usually initially appears with splenomegaly, hepatomegaly, and a normocytic, normochromic anemia. Extramedullary hematopoiesis is also a common finding, but is exceedingly rare in the major salivary glands. We report a case of extramedullary hematopoiesis in the parotid gland and discuss the differential diagnosis and characteristics of the disease.

Aged↗
PubMed1978

A case against nasal packing.

Nasal packing is included in most technical descriptions of septal and rhinoplasty surgery with little accompanying discussion of its indications and possible pitfalls. We believe that routine nasal packing is not an innocuous step. There are certain specific indications for its use but these are uncommon. We suggest that exclusion of packing is a wiser alternative in routine procedures. Over 800 cases of nasal surgery have been reviewed with fewer than 9% requiring packing. The indications for such packing are described as are the alternatives. Problems and complications attendant with its routine use are explored.

Humans↗
PubMed1977

Liposarcoma of the larynx: a multicentric or a metastatic malignancy.

The third case of liposarcoma of the larynx, this one arising from the preepiglottic space, is presented. The report is unique in so far as the patient previously had been treated for a liposarcoma in another anatomic region. The diagnosis in this case was in doubt until electron microscopic studies were done. Since the histopathology of the laryngeal and the previous liposarcoma were different, the question of metastasis versus multicentricity was raised. Other discussions of liposarcomas over the past three decades have not resolved this aspect of their behavior completely. In this instance, after considering avenues of metastatic spread in conjuction with the histopathology, it would appear that the laryngeal lesion was a second primary and not a metastasis.

Aged↗