Biomedical subjects

D G CAMERON

Publications and source records attributed to D G CAMERON.

At least 19 recordsLinked to original sources

PubMed1965

LATENT INFECTIONS WITH PLASMODIUM OVALE MALARIA.

Two cases of Plasmodium ovale malaria acquired in West Africa appeared as primary delayed attacks after one year's continuous residence in Canada. Both patients took full prophylactic doses of chloroquine before, during, and for several weeks after exposure. The inadequacy of the 4-aminoquinolines for protection against latent benign tertian malaria is noted, and the use of primaquine is recommended. Paroxysms occurred in the evening and were accompanied by severe muscle pain, features considered typical of ovale malaria. One patient showed electrocardiographic changes and clinical signs of cardiac malfunction; these disappeared following specific treatment for malaria. In this age of accelerated travel and international movements of people it is important that physicians in temperate regions be aware of the exotic infections of the tropics, as well as of the need for protective measures for travellers to areas where these diseases are endemic.

Africa, Western↗

PubMed1965

CONTINUING MEDICAL EDUCATION: SOME THOUGHTS ON SPONSORSHIP.

The proper role of departments of continuing medical education in the medical faculties of universities needs to be more clearly defined. Much of the initiative for the development of extramural postgraduate instruction in this country came from organized medicine. The individual practising doctor has traditionally made his needs known most effectively through his professional organizations and should be encouraged to continue to do so. The individual doctor, professional organizations, hospitals and medical schools are all vital elements in any successful program of continuing medical education. A variety of administrative patterns may well emerge, each adapted specially to the region it serves. With a sense of urgency and the co-operation of all concerned, rapid progress in this important field is clearly possible.

Education, Medical, Continuing↗

PubMed1963

BACTEREMIC SHOCK--A MEDICAL EMERGENCY.

Bacteremic shock is second in frequency only to myocardial infarction as a cause of hypotension and death in hospitalized medical patients. The clinical course is marked by fever, usually with chills, and hypotension with a full pulse and warm extremities, followed by shock, often resistant to treatment. Anticipation of this complication in patients with certain predisposing diseases or factors facilitates early recognition of the symptoms and signs of bacteremic shock and prompt treatment. Early and effective treatment of the offending infection often prevents progression of hypotension to the stage of frank vascular collapse.

Anti-Bacterial Agents↗

PubMed1963

INTESTINAL ABSORPTION OF TRITUM-LABELLED FOLIC ACID IN IDIOPATHIC STEATORRHEA: EFFECT OF A GLUTENFREE DIET.

The intestinal absorption of folic acid in patients with idiopathic steatorrhea was studied by the oral administration of tritium-labelled folic acid in a dosage of 15 mug./kg. Results were expressed as a percentage of the orally administered folic acid radioactivity excreted in the urine over 24 hours. The mean excretion of radioactivity in 38 normal subjects was 48.2 +/- 16.6% (mean +/- SD), whereas eight patients with untreated idiopathic steatorrhea excreted only 16.7 +/- 3.4% (mean +/- SE).The ability of the gluten-free diet to correct this absorptive defect was demonstrated by the finding of normal values in 11 patients in complete clinical remission for periods exceeding six months after institution of the diet. Serial studies in individual patients indicated that a significant improvement was obtainable in as short a period as two weeks following exclusion of gluten from the diet.

Administration, Oral↗

PubMed1963

Intestinal volvulus in idiopathic steatorrhea.

Volvulus of the intestine has recently been observed in three patients with idiopathic steatorrhea in relapse. Two patients gave a history of intermittent abdominal pain, distension and obstipation. Radiographic studies during these attacks revealed obstruction at the level of the sigmoid colon. Reduction under proctoscopic control was achieved in one instance, spontaneous resolution occurring in the other. The third patient presented as a surgical emergency and underwent operative reduction of a small intestinal volvulus. Persistence of diarrhea and weight loss postoperatively led to further investigation and a diagnosis of idiopathic steatorrhea. In all cases, treatment resulted in clinical remission with a coincident disappearance of obstructive intestinal symptoms. The pathogenesis of volvulus in sprue is poorly understood. Atonicity and dilatation of the bowel and stretching of the mesentery likely represent important factors. The symptoms of recurrent abdominal pain and distension in idiopathic steatorrhea necessitate an increased awareness of intestinal volvulus as a complication of this disease.

Abdominal Pain↗

PubMed1961