Biomedical subjects

D G Gallup

Publications and source records attributed to D G Gallup.

78 records · Page 5Linked to original sources

PubMed1978

Colposcopic evaluation of DES-exposed progeny at two large medical centers: the squamous neoplasia problem.

Two hundred eight patients with confirmed or suspected diethylstilbestrol exposure were examined colposcopically at two separate medical centers. Cervicovaginal ridges were present in 90 (43.3%) and ectopy was found in 188 (90.4%) of the patients. Evidence of vaginal adenosis was present in 122 (58.6%) of the cases. Seventy-four percent of the patients had abnormal colposcopic findings: 15.4% having columnar epithelium on the surface of the vagina and 66% having abnormal transformation zones (white epithelium, punctation, mosaic). Twenty patients (9.6%) were initially identified histologically as having squamous dysplasia. Subsequent review of the histologic material in these cases could document only two cases of significant squamous dysplasia, both severe, the remainder having immature, atypical metaplasia or possibly very mild dysplasia. This finding emphasizes the problems encountered in histologically differentiating squamous neoplasia from the peculiar metaplasia found in these patients, thereby making it difficult to establish whether these patients are at increased risk for the development of squamous neoplasia.

Adolescent↗

PubMed1978

Syphilitic cervicitis. A report of a case.

A case report of a young female who had a biopsy of a cervical lesion suspicious for malignancy is presented. After further evaluation, an initial diagnosis of Stage III sarcoma of the cervix was considered. The patient was eventually appropriately treated for a syphilitic chancre of the cervix. The pitfalls of diagnosis in this patient and other patients in the literature who have leutic cervicitis are stressed in order to alert the practicing gynecologist to this unusual location of a common veneral disease.

Adult↗

PubMed1977

Invasive adenocarcinoma of the uterine cervix.

A series of 33 infiltrative adenocarcinomas of the uterine cervix treated during the period from 1965 to 1970 is assessed and compared with a previous series from this institution and with series reported in the literature. The findings indicate that adenocarcinomas constitute and increasing proportion of cervical carcinomas and in this series make up 9.6% of all cervical carcinomas as compared with a previous figure of 5.5%. Five patients in the series were 32 years of age or less, and all had been receiving oral contraceptives for varying periods of time prior to the diagnosis of carcinomas. Radical surgery or irradiation treatment followed by extrafascial conservative hysterectomy in appropriate cases may offer increased survival for operable stages of adenocarcinoma, particularly in the presence of bulky lesions.

Adenocarcinoma↗

PubMed1976

Vaginal hysterectomy by an anterior colpotomy technic.

A simple, relatively unknown technic of vaginal hysterectomy using the anterior colpotomy approach is presented. Experience with this procedure at a small Naval hospital is described. Morbidity occurred in 6.6% of the patients. The advantages of this method of vaginal hysterectomy are summarized.

Adult↗

PubMed1976

Epithelioid sarcoma of the vulva.

An example of epithelioid sarcoma of the vulva in a 31-year-old female is reported. Treatment consisted of a radical vulvectomy and bilateral inguinal lymphadenectomy. Bilateral inguinal lymph node metastases were present. Criteria for the diagnosis of this unusual neoplasm are considered, and guidelines are suggested for its treatment.

Adenocarcinoma↗

PubMed1975

Carcinoma in situ of the vagina. A study and review.

A retrospective study has been carried out on 25 patients treated at the University of Michigan Medical Center for carcinoma in situ of the vagina. Intraepithelial carcinoma of the vagina occurred as a primary entity, following treatment for preinvasive and invasive carcinoma of the cervix, and following hysterectomy for benign disease of the uterus. These patients were treated with either radium implantation or some form of surgery. Five patients had recurrences. These 5 were all subsequently retreated and are alive and without evidence of further recurrent neoplasm. This series of carcinoma in situ of the vagina is compared to other reported series. Emphasis is directed toward the need for continued use of Papanicolaou smear cytology tests in posthysterectomy patients, regardless of the reason for hysterectomy.

Adult↗