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Biomedical subjects

D G Melrose

Publications and source records attributed to D G Melrose.

At least 19 recordsLinked to original sources

The stripping of varicose veins: a clinical trial of intermittent compression dressings.

This study compares a standard method of care for patients following excision and ligation of varicose veins with a new regimen which involves intermittent compression dressings. In a fully randomized between-patient prospective trial it has been found that the use of such dressings results in a significant reduction in postoperative pain and in the length of hospitalization and indicates that such dressings may improve the healing of surgical wounds.

Adult↗

Fibrinolytic response to surgery. Labile and stable patterns and their relevance to post-operative deep venous thrombosis.

Fibrinolytic activity after elective abdominal surgery was studied in 53 middle-aged cancer-free patients. The pattern of their response demonstrated both stable and labile populations. In 10 of the 13 patients in whom fibrinolytic activity fell rapidly to below 5-6 units, deep venous thrombosis (D.V.T.) developed on the first postoperative day. This suggests that reduced fibrinolytic activity after operation is involved in the establishment of postoperative D.V.T. and that the incidence of early thrombosis could be reduced by enhancement of postoperative levels of fibrinolytic activity.

Clot Retraction↗