Montserrat. An offshore medical school.
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Biomedical subjects
Publications and source records attributed to D G Model.
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Two methods for the measurement of plasma creatine kinase MB (CK-MB) activity were compared for analytical performance, cost, practicality, and diagnostic correlation with clinical and electrocardiographic findings in patients admitted to the coronary care unit of a district general hospital. The methods were column chromatography and immunoinhibition. Both methods were found acceptable, and the method to be adopted would depend on the staff arrangements and resources available in the laboratory.
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Oral disopyramide given prophylactically following myocardial infarction has been compared with placebo in a double-blind trial using continuous-tape monoriting of the electocardiogram. It caused a significant reduction in the incidence of ventricular arrhythmias and of the various degrees of heart-block. There was a significant reduction of reinfarction during hospital stay in patients who had received disopyramide. Disopyramide appears to be a safe and effective oral therapy in the prevention of potentially serious arrhythmias following myocardial infarction.
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Small numbers of seven species of bacteria commonly causing bacteraemia in man were inoculated into fresh human blood, and then cultured by a standard method used for diagnostic blood culture. Prior warming of the medium did not improve the recovery of the inoculated bacteria and it is suggested that such warming is not required when performing diagnostic blood culture.
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