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Biomedical subjects

D G Mustafin

Publications and source records attributed to D G Mustafin.

At least 19 recordsLinked to original sources

[Clinical variants and treatment of urological sepsis].

The paper describes current clinical features of urological sepsis, factors provoking sepsis in urological patients, leading laboratory and clinical characteristics of the disease, principles of treatment and its results.

Adolescent↗

[Current approaches to conservative therapy of acute infectious lung destruction].

Differential programs of conservative treatment (antibacterial in combination with sanatorium) including correction of immune deficiency, detoxication, quantum hemotherapy resulted in appreciable responses in 84.8% out of 894 patients with acute destruction of the lungs. Radical surgery was performed in 67 (7.5%) patients. Specific features of the treatment according to intensive conservative schemes are presented for 484 patients with acute pulmonary abscess, 282 with staphylococcal pulmonary destruction, 106 with septic pulmonary destruction and 22 with pulmonary gangrene. Total lethality reached 7.7%.

Acute Disease↗

[Clinical aspects of septic lesions of the lungs].

Clinicoroentgenological variants of pulmonary complications were revealed in 96 (81%) out of 118 sepsis patients. In 55% of cases the disease emerged due to staphylococcal infection. Sepsis lesions of the lungs were analyzed clinically and classified according to respiratory insufficiency. The treatment oriented on pulmonary sepsis resulted in lowering of mortality (up to 17%). Measures to improve early diagnosis and to promote intensive treatment are under discussion.

Acute Disease↗

[Stimulation of the synthesis of C-reactive protein using pyrogenal in non-neoplastic diseases and cancer of the lungs].

Method of immunodiffusion titration of rabbit monospecific antiserum (The I. M. Mechnikov Central Research Institute of Vaccines and Sera of the USSR Ministry of Health) in agar was used to measure blood C-reactive protein (C-RP) level in patients with acute pneumonia (32), protracted pneumonia or activation of chronic non-specific lung pathology (101) and lung cancer (153) after a 3-4-week course of complex antiinflammatory treatment and a 10-14-day course of immunostimulation with pyrogenal (The N. F. Gamaleya Research Institute of Epidemiology and Microbiology). A decrease in the incidence (from 81.2% to 14.2%) and level (from 1.4 +/- 0.3 to 0.3 +/- 0.03 mg%) of C-RP was observed in cases of non-tumor pathology whereas in patients with lung cancer those values rose in step with tumor progression (from 72.2% and 0.4 +/- 0.07 mg% at stage I to 96.3% and 1.2 +/- 0.12 mg% at stage IV). Treatment with pyrogenal allowed to identify C-RP in patients with false-negative reaction in all subgroups. Two-week dynamic C-RP curves characterizing non-tumor and tumor pathology of the lung were plotted.

Anti-Inflammatory Agents, Non-Steroidal↗

[Treatment of surgical infection complicated by metastatic abscesses of the lung].

The clinical and X-ray features of pleuropulmonary complications of surgical sepsis are described on the basis of examination and treatment of 66 patients. Metastatic destruction of the lungs in the form of multiple abscesses and bullae prevailed in acute sepsis, extensive confluent focal pneumonia in sepsis taking a violent course, and formation of abscesses in aspiration and atelectatic pneumonias. Pleural complications occurred in 23 patients. Organization of purposeful treatment reduced mortality to 18.5%. Among 53 patients who were discharged from the clinic 48 had residual bullo-sclerotic changes in the lungs.

Adolescent↗

[Pulmonogenic sepsis with a metastatic splenic abscess in bronchial asthma].

The authors observed a patient with bronchial asthma who developed acute pulmonary pyodestruction with generalization of the infection, a splenic abscess and drug allergy against prolonged corticosteroid therapy. Diagnostic potentialities, necessary intensive care measures and long-term effects of these complications were discussed.

Abscess↗