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Biomedical subjects

D G Pasechnik

Publications and source records attributed to D G Pasechnik.

5 recordsLinked to original sources

[The morphological characteristics of endocrine-cell cancers of the large intestine].

Histological variants of colon carcinoma depending upon the quantity of endocrine cells are distinguished on the basis of 66 malignant epithelial colon tumours morphological investigation. Special emphasis was made on the characteristics of the endocrine cell carcinoma, combined tumours with a combination of glandular and endocrine components, and amphicrin neoplasms. A trabecular-glandular variant of endocrine cell carcinoma is found to be predominant in the colon. The criteria are suggested for the identification of endocrine-cell tumours.

APUD Cells↗

[Modern histological classification of renal neoplasms].

The review presents current literary information on basic forms of kidney cancer (clear cell carcinoma, chromophil or papillary cancer, chromophobe renal cell carcinoma, oncocytoma, Bellini carcinoma, sarcomatoid carcinoma and neuroendocrine carcinoma), their morphological characteristics and principles of classification. Modern histological classification of renal cancer is based on immunohistochemical evidence on markers of various nephron segments, this allowing to specify histogenesis of separate forms of renal cell carcinoma. In addition, cytogenetic studies of renal carcinoma reveal correlations between genetic changes in cancer cells and tumor phenotype found at light microscopy. Thus, current classification of renal carcinoma characterizes biology of these neoplasms. This should be taken into account in prognostication and design of new treatment methods.

Humans↗

[Kidney carcinosarcoma].

A kidney tumour in a 36 year old female is described. The tumor was soft, of gray-brown color, size 12 x 11 cm. Histological, immunohistochemical and ultrastructural findings have demonstrated the signs of biphasic epithelial and mesenchymal cell differentiation. These data allowed the authors to define this tumor as a renal carcinosarcoma. Histogenesis of this tumor and differential diagnosis with other malignant renal tumors are discussed.

Adult↗