PubMed Health⌕ Search

Biomedical subjects

D G Sims

Publications and source records attributed to D G Sims.

43 records · Page 3Linked to original sources
PubMed1976

Massive chronic feto-maternal bleeding associated with placental chorioangiomas.

After pregnancy complicated by polyhydramnios and the antenatal discovery of a very large placenta a newborn infant suffered from anemia, thrombocytopenia and hypoproteinemic edema, and was successfully treated by exchange transfusion. The placenta contained two chorioangiomas and there was diffuse placental hypertrophy with edema and patchy chorioangiomatosis. There was evidence of major chronic feto-maternal bleeding which could be the explanation for most of the hematological and biochemical problems which occurred. The child was developing normally at subsequent follow-up aged 15 weeks.

Anemia↗
PubMed1976

Multiple major cerebral artery thromboses with profound thrombocytopenia in acute leukaemia.

A child with acute lymphoblastic leukaemia complicated by prolonged gastrointestinal and skin haemorrhages due to profound thrombocytopenia finally died of thrombotic occlusions of major cerebral arteries due to mucormycosis. Biopsy of any suspect lesion is needed urgently before prolonged therapy with amphotericin B is started. So far there have been no cures in childhood.

Autopsy↗
PubMed1976

Echovirus 19 infection in infants under six months.

Twenty-four infants under 6 months infected with echovirus 19 are described, They were the youngest of the many children admitted to hospitals in Newcastle and Gateshead during an epidemic in the north-east of England in 1974. Generally, the younger the child the more severe the illness, which affected the upper respiratory tract, the gut, the skin, and the meninges, and sometimes caused as state of collapse resembling septicaemic shock. Polymorphonuclear pleocystosis of the cerebrospinal fluid (CSF) sometimes suggested bacterial meningitis, so that antibiotics were given in 38% of cases. The virus was recovered with a high success rate from nasopharyngeal secretions, CSF, and stool.

Age Factors↗
PubMed1975

Hospital cross-infection on children's wards with respiratory syncytial virus and the role of adult carriage.

A further 18 children who acquired respiratory syncytial (R.S.) virus infection on general paediatric wards have been identified, bringing the total number of hospital cross-infections by this virus to 46 for the last 3 annual R.S. virus epidemics on Tyneside. 25 of these 46 illnesses involved the lower respiratory tract. Carriage of R.S. virus by staff and visitors was studied on one ward, and appeared to be responsible for at least 2 and probably 4 of the 6 cross-infections detected on this ward. Methods for controlling the transmission of virus by adults on children's wards are discussed.

Carrier State↗
PubMed1975

Congenital midline scalp and skull defect.

A family with multiple congenital scalp defects, over two generations and probably genetically determined, is described. Although alarming in appearance, surgical intervention is not indicated at least for small lesions. The risk of haemorrhage and meningitis is emphasized.

Adult↗