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Biomedical subjects

D Gairdner

Publications and source records attributed to D Gairdner.

At least 19 recordsLinked to original sources
PubMed1979

The rhesus story.

Explore the source record for details and available documents.

Blood Transfusion, Intrauterine↗
PubMed1978

A notable case of nephrosis.

How a boy of 10 developed nephrosis more than 60 years ago, how he came to be seen by Sir Frederic Still with interesting later consequences, how his nephrosis cleared following measles, and how all this led to his becoming a distinguished paediatrician is told in a case history based on the diary kept by the boy's mother.

Child↗
PubMed1977

Assessment of total body fat in infancy from skinfold thickness measurements.

A formula is given, allowing a value for total body fat to be calculated from skinfold thickness measurements at two sites (subscapular and triceps), in conjunction with nine body dimensions. For newborn infants total body fat so calculated accorded satisfactorily with published data from cadaver analyses. The formula has been tentatively applied to infants up to the age of 40 weeks, and to preterm infants. The difference between the growth of male and female infants was analysed in a series of 27 normal infants; the greater growth of musculoskeletal tissue in the male contrasted with the relatively greater growth of fat tissue in the female.

Adipose Tissue↗
PubMed1976

IgA deficiency in one of identical twins.

A disease resembling childhood coeliac disease occurred in one of identical twins. When the twins were investigated at the age of 23 the initial diagnosis could not be substantiated but the twin who had been ill had selective IgA deficiency. Differences dating from early infancy may have been a result of the discordance for IgA deficiency. Thus in some patients environmental influences may be important in either the initiation or the perpetuation of the deficiency.

Adolescent↗
PubMed1975

Size of adipose cells in infancy.

Seventy-three samples of adipose tissue from 59 infants, aged from 25 weeks' gestation to 18 months of age, were obtained at necropsy, or at operations, or by needle biopsy. Adipose cell size was measured by microscopy. During fetal life the mean cell diameter increases from about 40 mum at 25 weeks' gestation to 50-80 mum at term. Adipose cells from the buttocks are larger than those from abdominal wall. After birth, adipose cell size continues to increase so that by 3 months the mean cell diameter is about 90 mum. Observations made on infants that had been born preterm showed that the growth of adipose cells proceeds at the same rate whether development in intrauterine or extrauterine.

Abdominal Muscles↗
PubMed1973

Predictive factors in open myelomeningocele with special reference to sensory level.

A total of 113 cases of open myelomeningocele operated on shortly after birth were followed up and the 80 survivors (71%) were assessed one and a quarter to seven and a half years later. Their disability was classified in terms of mobility, intelligence, continence, and major complications; these when combined provided an assessment of overall disability. The overall disability of the survivors was minimal in 6%, moderate in 40%, severe in 39%, and very severe in 15%.A number of clinical features present at birth were analysed for their predictive value. Of these the sensory level, which frequently differed from both external and radiological levels of the lesion, correlated with the outcome in terms of mobility, intelligence, continence, major complications, and overall disability; and also with deaths caused by renal failure.A policy of confining operation to those patients with a reasonable chance of achieving independence would involve selecting for treatment a minority of all infants born with open myelomeningocele.

Child↗