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Biomedical subjects

D Galler

Publications and source records attributed to D Galler.

6 recordsLinked to original sources
PubMed2005

Rewarming of healthy volunteers after induced mild hypothermia: a healthy volunteer study.

OBJECTIVES: The study compares the efficacy of two active and one passive warming interventions in healthy volunteers with induced mild hypothermia. METHODS: Eight volunteers were studied in a random order crossover design. Each volunteer was studied during re-warming from a core temperature of 35 degrees C with each of: a radiant warmer (Fisher & Paykel); a forced air warmer (Augustine Medical), and a polyester filled blanket, to re-warm. RESULTS: No significant differences in re-warming rates were observed between the three warming devices. It was found that the subject's endogenous heat production was the major contributor to the re-warming of these volunteers. Metabolic rates of over 350 W were seen during the study. CONCLUSIONS: For patients with mild hypothermia and in whom shivering is not contraindicated our data would indicate that the rate of re-warming would be little different whether a blanket or one of the two active devices were used. In the field, this may provide the caregiver a useful choice.

Adult↗
PubMed2005

Brugada syndrome following tricyclic antidepressant overdose.

The Brugada syndrome, a pro-arrhythmogenic repolarization abnormality, is becoming increasingly recognised as a cause of collapse and sudden cardiac death. We report a case of a 48-year-old man with a tricyclic overdose and a delayed presentation of the Brugada pattern in the ICU. This case raises the need for clinicians to be aware of the Brugada pattern and those patients potentially at risk.

Antidepressive Agents, Tricyclic↗
PubMed1996

Relationship between the humidity and temperature of inspired gas and the function of the airway mucosa.

OBJECTIVE: To review the available literature on the relationship between the humidity and temperature of inspired gas and airway mucosal function. DATA SOURCES: International computerized databases and published indices, experts in the field, conference proceedings, bibliographies. STUDY SELECTION/DATA EXTRACTION: Two hundred articles/texts on respiratory tract physiology and humidification were reviewed. Seventeen articles were selected from 40 articles for inclusion in the published data verification of the model. Selection was by independent reviewers. Extraction was by consensus, and was based on finding sufficient data. DATA SYNTHESIS: A relationship exists between inspired gas humidity and temperature, exposure time to a given humidity level, and mucosal function. This relationship can be modeled and represented as an inspired humidity magnitude vs. exposure time map. The model is predictive of mucosal function and can be partially verified by the available literature. It predicts that if inspired humidity deviates from an optimal level, a progressive mucosal dysfunction begins. The greater the humidity deviation, the faster the mucosal dysfunction progresses. CONCLUSIONS: A model for the relationship between airway mucosal dysfunction and the combination of the humidity of inspired gas and the duration over which the airway mucosa is exposed to that humidity is proposed. This model suggests that there is an optimal temperature and humidity above which, and below which, there is impaired mucosal function. This optimal level of temperature and humidity is core temperature and 100% relative humidity. However, existing data are only sufficient to test this model for gas conditions below core temperature and 100% relative humidity. These data concur with the model in that region. No studies have yet looked at this relationship beyond 24 hrs. Longer exposure times to any given level of inspired humidity and inspired gas temperatures and humidities above core temperature and 100% relative humidity need to be studied to fully verify the proposed model.

Animals↗
PubMed1992

Health reforms.

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Health Services Administration↗
PubMed1987

Arterial oxygen saturation during general anaesthesia for paediatric dental extractions.

Arterial oxygen saturation (SaO2) was measured in 50 healthy children undergoing dental extractions under general anaesthesia. An inhalational anaesthetic technique was employed, with an inspired oxygen concentration of 33%. There were decreases in SaO2 of greater than 5% of the baseline value in 70% of patients, and greater than 10% in 26% of patients. The majority of these decreases were associated with teeth extractions or during placement of dental prop and pack. Non-Caucasian children showed a significantly (p less than 0.05) greater maximum decrease in SaO2 from baseline value compared to Caucasian children. The maximum decreases in SaO2 from baseline value in children anaesthetised by supervised dental students, and in children whose extractions were performed by dental students, were significantly (p less than 0.05) greater than in children whose anaesthetic and surgery were performed by members of staff.

Adolescent↗