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Biomedical subjects

D Galloway

Publications and source records attributed to D Galloway.

31 records · Page 2Linked to original sources
PubMed1988

Neurologic return versus cross-sectional canal area in incomplete thoracolumbar spinal cord injuries.

Twenty-four patients with incomplete spinal cord injuries secondary to burst fractures of the thoracolumbar spine were reviewed an average of 26 months after their injury. No patient had had a specific attempt to decompress neural elements but the majority had posterior instrumentation and fusion for spine realignment and stabilization. The amount of neurologic recovery in each patient was compared to the final area of the spinal canal as determined by CT scan. It was concluded that there was no correlation between neurologic improvement and the amount of spinal canal encroachment. In addition, posterior instrumentation to realign the spine will usually restore canal patency to greater than 50% of normal.

Adult↗
PubMed1988

Scalp colonization by Trichophyton tonsurans in an urban pediatric clinic. ?Asymptomatic carrier state.

Random culturing of the scalp in 200 healthy children in a large metropolitan children's hospital revealed that eight (4%) of the patients had cultures that were positive for Trichophyton tonsurans variety sulfureum. Infections were not clinically apparent and were asymptomatic. All of the patients with positive cultures were black and six braided their hair. Trichophyton tonsurans appears to exist in an asymptomatic state in this well-defined population of children.

Black People↗
PubMed1986

Bowel adenocarcinoma in a patient with cystic fibrosis.

Cystic fibrosis (CF) is an autosomal recessive condition affecting one in 2,000 live births in the UK. There are few reports of malignant tumours in this condition probably because, until recently, the majority died before the age of 30 years as a result of recurrent and chronic bronchopulmonary infection with impaired growth and development and resistance to infection due to pancreatic malabsorption. We describe an adult male with CF who died from an adenocarcinoma affecting the ileocaecal region of the bowel.

Adenocarcinoma↗
PubMed1984

Herpes simplex virus types 1 and 2 homology in the region between 0.58 and 0.68 map units.

The homology between herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2, respectively) DNA between 0.58 and 0.674 map units was compared by Southern and dot blot analysis with DNA of one type of virus as a hybridization probe against the other type. Regions of high homology were interspersed with regions of detectably lower homology. However, only one region (between 0.647 and 0.653 map units) contained few or no homologous sequences. In situ RNA blot hybridization demonstrated that the mRNA species transcribed in the right-hand portion of the region are homologous between HSV-1 and HSV-2, as was previously found for the left-hand portion. A 2.7-kilobase HSV-2 transcript in the right-hand portion of the studied region was clearly that encoding HSV-2 glycoprotein C. Comparative nucleotide sequence analysis of specific regions demonstrated that homologous translational reading frames could be identified in the virus types. This analysis also demonstrated that homology could be abruptly lost outside such reading frames. Comparison of regions of homology with published HSV-1 transcription maps suggests that there can also be large divergence within translational reading frames. Some, but not complete, sequence homology was seen in the putative promoter sequence for the 730-base HSV-1 mRNA mapping to the right of glycoprotein C and the corresponding HSV-2 DNA. This suggests that the rather strict conservation of promoter sequences between homologous HSV-1 and HSV-2 transcripts seen in other regions of the genome may not be a necessary feature between these virus types.

Base Sequence↗
PubMed1984

Mental health, absences from work, stress and satisfaction in a sample of New Zealand primary school teachers.

A study of 296 primary school teachers in New Zealand revealed a very low correlation between mental health, measured by the General Health Questionnaire, and absence from work. The correlations between mental health and feelings of stress at work and between mental health and job satisfaction were higher. The most highly rated sources of stress were ranked, as were the most highly rated sources of satisfaction. It is suggested that teachers' experiences of stress are associated with lack of satisfaction with intrinsic aspects of their job rather than with dissatisfaction at their conditions of employment.

Absenteeism↗
PubMed1983

Research note: truants and other absentees.

Truants living in a depressed urban area are compared with Other Absentees from school living in the same area. The results show few differences in the social and financial circumstances of the two groups but considerable differences in the children's behaviour and in family relationships. The results are discussed in the light of other research which distinguishes truants from school refusers.

Absenteeism↗
PubMed1982

Endotoxaemia and complement activation in acute pancreatitis in man.

Twenty-four patients who experienced 26 attacks of acute pancreatitis were studied. Endotoxaemia, as measured by the limulus lysate assay, was present in 13 of the attacks. Six out of seven patients with systemic complications of the disease had endotoxaemia. C3 catabolism was increased in all 26 attacks of pancreatitis, and a falling level of C3 during attacks of severe pancreatitis was associated with a fatal outcome. There was statistical evidence of more complement activation in serum samples taken when patients had positive limulus lysate tests than when endotoxin was not detected in their blood.

Acute Disease↗
PubMed1981

Topographic association of fibronectin with elastic fibers in the arterial wall. An immunohistochemical study.

Rabbit antibodies to human fibronectin which recognize tissue fibronectin and lack species-specificity have been employed to localize this molecule in the arterial wall of different animal species by indirect immunofluorescence. Fibronectin has been found to be consistently associated with both the inner and external aspects of the internal elastic membrane of large size arteries in mammals. Only scanty staining for fibronectin has been detected in collagen rich areas of the vessel wall, i.e. adventitia. This topographic association of fibronectin and internal elastic membrane is maintained in large size arteries (aorta, truncus arteriosus) of all species studied, including reptiles, amphibia and fish. The present findings suggest that fibronectin may mediate the contraction of vessel wall structures (i.e. elastic membranes) which lack an intrinsic contractile activity.

Amphibians↗
PubMed1980

Clinical metrology--a future career grade?

Clinical metrologists have been employed in Leeds for the past seven years. They have come to assume increasing responsibility, particularly in the conduct and recording of clinical trials in the rheumatic diseases. Their work can be extended to the planning of trials, practical procedures, and other research activities. Analysis of 20 applications for a post that recently fell vacant at Leeds suggests that many married women, highly qualified professionally, who have completed their families, would welcome the opportunity to return to parttime nursing duties in "social hours". Increased responsibility and job satisfaction provided by the post compensate for a reduction in salary. Clinical metrology may be a new career grade in the National Health Service that allows for more careful monitoring of patients with constancy that cannot be achieved with rotating junior medical staff. Physicians can be released from the routine of follow-up, so that they have more time for diagnosis, management of complex problems, and research.

Adult↗