Biomedical subjects

D García Compeán

Publications and source records attributed to D García Compeán.

3 recordsLinked to original sources

PubMedDate not supplied

[Severe diarrhea in AIDS treated with a somatostatin analog. Report of a case].

We herein report a 30 years old male patient with AIDS and Cryptosporidium diarrhea diagnosed by intestinal biopsy. After some days of unsuccessful conventional anti-diarrheal treatment, an analog of somatostatin (octreotide acetate) Sandostatin was started. The stool volume and the bowel movements decreased dramatically and in spite of some collateral effects the patient could be clinically improved and discharged from the hospital.

Acquired Immunodeficiency Syndrome↗

PubMedDate not supplied

[Gastrointestinal hormones].

Recently, knowledge about the physiological and physiopathological role of some already known gastrointestinal hormones has been increased. At the same time, new biologically active substances (peptides) have been isolated from the gastrointestinal tract and pancreas. Some hormones that were thought to be restricted to the digestive system have been identified in the brain and some peptides localized in the nervous terminals in the myenteric plexuses, actively participate in the biological process of the gut. These findings have made the comprehension of this field more complicated. As a consequence of this, the term of "gastrointestinal endocrinology" is emerging. In this article we will discuss some general concepts of gastrointestinal and pancreatic hormonal physio-pathology and individually, about the role of some hormones and peptides in the normal and abnormal biological process. We emphasize the importance of biochemical diagnosis of those abnormalities.

Gastrointestinal Hormones↗

PubMedDate not supplied

[Primary liver cancer. Its epidemiological, clinical and biochemical characteristics].

Epidemiological, clinical, biochemical and topographic features of primary hepatic cancer (PHC) were reviewed retrospective and prospectively in this study. This review consisted of 76 patients from 1971 to 1990. Forty nine males and 27 females. The mean age was 66.1 +/- 11.7 years. Hepatocellular carcinoma (HC) was the most frequent histological type (84.1%), followed by cholangiocarcinoma (87.7%). Mixed carcinoma and hepatoblastoma were 4.3 and 2.9% respectively. The prevalence af PHC among 1485 autopsies was 0.74%. The most frequent sites af metastasis were the lungs (66%) and portal vein (50%). Hepatocellular carcinoma was associated to cirrhosis in 80% of the cases. A syndrome including asthenia, weight loss, hepatomegaly and cholestasis was identified in most of the patients, and alkaline phosphatase was the most frequently disturbed laboratory test. 60% of tumors were bilateral and none of the solitary tumors had less than 5 cms in diameter. 20% of HC showed normal serum levels of AFP (< 20 ng/ml). 40% had at least one of the markers of B virus hepatitis in serum.

Age Distribution↗