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Biomedical subjects

D Gardeur

Publications and source records attributed to D Gardeur.

At least 19 recordsLinked to original sources
PubMed1992

[Orbital myositis, recurrence of Whipple's disease].

Whipple's disease, a chronic systemic and multi-organ disease can be associated with ophthalmological manifestations with or without CNS involvement. Myositis rarely occurs during Whipple's disease. Antibiotic treatment prevents CNS recurrence. We report here the association of an orbital pseudotumor with Whipple's disease. This myositis was discovered on a follow-up CT examination. It appeared only one year after the end of a long course of antibiotic treatment, but it resolved within a few weeks when treatment was reintroduced. Relations between these two diseases are discussed.

Eye Diseases↗
PubMed1985

[Cerebral aspergilloma. X-ray computed tomographic aspect. Apropos of a case. Review of the literature].

Cerebral aspergilloma of initial sinus origin developed in a patient with mixed cell leukemia. Computed tomography imaging showed signs of a cystic multitumoral syndrome with a crown-shaped filling image without peritumoral edema. Follow up of cerebral lesions during medical treatment was by repeated CT scans, with progressive regression of images over a period of 8 months. The patient died after recurrence. Aspergilloma is seen mainly in patients with alternating immunity defenses.

Aspergillosis↗
PubMed1983

[Primary lymphoma of the central nervous system. Apropos of 8 cases].

Eight cases of intracranial primary lymphoma are reported. This condition accounts for 1.6% of all lymphomas. Although diagnosis is only confirmed by cerebral biopsy or surgical excision, it may be suggested by CT scan in multifocal forms. No localizations were demonstrated outside the CNS upon thorough clinical and radiological investigations or postmortem examination. Prognosis is poor: 5 patients died within four months. Tumor size and meningeal invasion are of more prognostic significance than the histological type. The authors advocate conventional radiotherapy delivering 45 000 grays over 5 weeks. Chemotherapy must be added in huge tumors or when meningeal invasion is present.

Adult↗
PubMed1983

Digital intravenous subtraction angiography of intracranial arteriovenous malformations.

Twenty-one intracranial arteriovenous malformations (17 pial, 3 dural, 1 mixed) have been studied by digital intravenous subtraction angiography (DIVA). A comparison with conventional arteriography has been performed. In this series DIVA was 100% diagnostic for AVM. However DIVA missed some small arterial pedicles (1 lenticulostriate, 1 thalamoperforating, 1 anterior choroidal artery and 2 pharyngeal arteries). Sectorial analysis of AVM needs selective arteriography. DIVA is a good method for screening and follow-up of intracranial AVM, but selective arteriography is often still necessary to complete the pre-operative evaluation.

Adult↗
PubMed1983

Cranial computed tomography in the phakomatoses.

The authors present the CT findings in their personal series of 77 cases of neurofibromatosis, 34 cases of tuberous sclerosis, and 16 cases of Sturge-Weber disease. These findings are extensively illustrated and compared with those reported in the literature.

Adolescent↗
PubMed1983

["Sub-angular" alexis and associated neuropsychologic signs: clinical and tomodensitometric study].

A clinical case of alexia without agraphia is reported. The computerized tomography (CT) showed a left sub-cortical parieto-occipital hemorrhage. The cortical lesion probably involved the posterior part of the angular gyrus but spared the medial occipital cortex. There was no evidence of a corpus callosum lesion. The clinical findings associated with the alexia and the localisation of the haematoma could be compared to the case reported by Greenblatt as a "subangular alexia" and considered as a disconnection of the left angular gyrus from right angular gyrus and both left and right occipital areas. The semiological aspects of the present case have been found to consistently differ from the classical forms of alexia usually described. Some common features with phonological alexia have been observed.

Aged↗
PubMed1983

[96 cases of spontaneous medical cerebral hemorrhage. Diagnostic and therapeutic experience].

Prognosis in a homogeneous series of 96 cases of non-traumatic cerebral hemorrhage admitted to a neurosurgical department within 6 to 24 hours of onset was assessed by studying possible correlations between clinical condition (grade I: conscious; grade II: somnolent; grade III: comatose; grade IV: comatose with signs of brain stem involvement) and computed tomography findings (site, extension, size of hemorrhage; degree of edema and of mass effect; presence of hydrocephalus or ventricular hemorrhage). It was possible to distinguish effects due to destruction and/or compression of functional cerebral regions for a given clinical picture, and to apply these data to determine types of therapy and surveillance according to 3 time-periods. During the first 48 hours there was almost perfect agreement between the severity of the clinical picture and the degree of cerebral destruction (62,6 p. 100 of grade IV, 27,7 p. cent of grade III died). Only patients in grade III with temporal hemorrhage directly menacing the brain stem were operated upon. From the 3rd to the 7th day surveillance was based on clinical findings and computed tomography, repeated in principle on the 3rd and 7th days. Patients operated upon during this period were those in whom clinical signs and/or effects due to mass effect as seen on the CTscan were becoming worse. The third period, lasting from the 8th to the 21st day, was that during which the vital prognosis was generally no longer affected, and indications for surgery were functional in nature. The prognostic value of measurements of intracranial pressure is discussed.

Adult↗
PubMed1983

[Acute pseudotumoral demyelination with regressive attacks].

A 14 year-old boy presented, at a 3 month interval, with 2 episodes of hemiplegia of rapid onset. The first time, CT scan revealed a large parietal "tumor", shown to be pseudocystic at surgery, and histologically proven as a demyelinating disease. During the second attack, CT scan showed a similar but contralateral lesion, regressing completely under steroid treatment. 40 months after the onset of the disease, the child's life and intelligence are normal.

Acute Disease↗
PubMed1982

[Computed tomography of the head in gunshot wounds. Thirty-three cases (author's transl)].

The authors report a series of 33 cases of craniocerebral lesions secondary to projectiles injuries studied by means of CT scan. Ct scans demonstrate the path of the missile, destructions of deep cerebral parenchyma, dissections of with matter (intra-cerebral bubble) and reactive oedema. Prognostic incidence of CT is discussed. CT scan helps to choose the best therapeutic approach as regards each particular case.

Adolescent↗
PubMed1982

The current potential of neuroradiology in the diagnosis of tuberous sclerosis.

Computed tomography has proved very valuable in the diagnosis of central nervous system changes in tuberous sclerosis. A full analysis of the CT findings in 34 cases is presented. Intracranial calcifications--periventricular, corticosubcortical, within the white substance or in the posterior cranial fossa--were the most frequent finding, followed by parenchymal hypodensities and tumors. Hydrocephalus and atrophy, focal or diffuse, were rare.

Brain Diseases↗
PubMed1982

[Simplified technic for stereotaxic biopsy of hemispheric tumors].

Stereotaxic biopsy of cerebral tumors has been considerably facilitated by the use of CT scanner. A new method is described using the CT section in the horizontal or oblique plan of biopsy. When this has been determined, it is possible to define a trajectory, calculated by the CT scan computer, with external landmarks marked on the skin. This method is possible with any kind of CT apparatus; the surgical biopsy is performed in the operating room with a simple stereotaxic frame square-shaped and fixed in the plan of the CT section. The biopsy needle may be oriented in an antero-posterior or medio-lateral direction. This method has been used in 33 patients, leading to as precise histological diagnosis in 30 cases. No complications have been noted, except for transient neurological deterioration in two cases, due to local edema. Hemorrhage have not been observed. The topographical precision of the method was verified by the injection of lcc of air followed by a post-biopsy CT scan. This technique seems particularly valuable for the diagnosis of deep or wide spread hemispheric tumors, non indicated for open surgery.

Biopsy, Needle↗