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Biomedical subjects

D Gehrig

Publications and source records attributed to D Gehrig.

7 recordsLinked to original sources
PubMed2003

[Hemorrhagic shock due to splenic rupture in non-severe acute pancreatitis].

A 54-year old man was hospitalized for a non severe acute pancreatitis of alcoholic aetiology. Four days after his admission, whilst symptoms and laboratory findings were on the mend, he suddenly presented with acute shock. A CT-scan demonstrated a massive haemoperitoneum due to splenic rupture which necessitated an emergency splenectomy. The causes of shock in acute pancreatitis and the factors that may lead to splenic rupture are discussed. In this patient, a possible role of the non-steroidal anti-inflammatory treatment remains undetermined.

Acute Disease↗
PubMed1997

[Bisalbuminemia disclosing primary hyperparathyroidism with fistulized pancreatic false cyst].

Discovery on a protein electrophoregram of a bisalbuminemia can orientate according to its migration fast or slow to an hereditary mutation of an amino acid, or an acquired form by excess of beta lactamines due to renal insufficiency or by the rupture of a pancreatic pseudocyst in the peritoneum. This is this late mechanism that we report in this case of bisalbuminemia related to an opened pancreatic pseudocyst secondary to an adenoma of the parathyroid gland.

Blood Protein Electrophoresis↗
PubMed1990

[Organ donation for transplantation. Survey of opinions of physicians and paramedics in the province of Vaud].

In 1987, two media campaigns were organized in Switzerland to promote donor cards. The purpose of this study was to test their impact on the medical community. Questionnaires were sent to qualified practitioners, doctors in training and intensive care nurses. It is concluded that the campaigns for organ donation must be repeated and that their quality can be improved. It is however more urgent to improve the level of knowledge among doctors and other health professionals.

Attitude of Health Personnel↗
PubMed1977

[A family with hereditary hypofibrinogenemia].

A family with congenital hypofibrinogenemia (fibrinogen levels of 60-90 mg%) has been studied. Out of 19 members tested, 11 exhibit this trait, which follows a strictly autosomal-dominant pattern of inheritance. Congenital hypofibrinogenemia appears to be a separate entity which can be distinguished from heterozygous individuals of congenital afibrinogenemia and from congenital dysfibrinogenemia. A bleeding tendency of clinical significance is observed only during major surgery or after severe injury.

Adolescent↗
PubMed1977

[Anti-phospholipid antibodies as a cause of immunologic thrombopenia and thrombopathies].

The simultaneous occurrence of platelet antibodies (ab) and a circulating "antithromboplastic" anticoagulant in a patient with thrombocytopenia led to the hypothesis that antiphospholipid ab may be causing both phenomena. Of 55 sera obtained from thrombocytopenic patients exhibiting a positive microtest for complement fixation (CFT) with platelets, 37 also gave positive results with highly purified phospholipids (Phl) used as antigen. In order to further evaluate the role of Phl, 40 different liposome suspensions obtained by sonication of various mixtures of Phl (with/without addition of cholesterol) were tested as antigen in the CFT with 11 selected sera, and as platelet factor 3 (PF3) reagent in the partial thromboplastin time test with normal plasma. Eight liposome preparations with PF3 activity (all containing phosphatidyl-serine) were equally active as antigen (ag) in the CFT. Liposomes composed of phosphatidyl-ethanolamine and sphingomyeline delivered ag-activity only. Since the two substances are accessible components of the outer membrane surface of thrombocytes, anti-Phl-ab may well bind to platelets in vivo, causing thrombocytopenia. Coagulation-inhibiting activity of these ab could be directly demonstrated in a PF3-test system (thrombocytopathy caused by PF3 inhibition). The identity of antithromboplastic anticoagulant and anti-Phl-ab was further substantiated by immunoabsorption, since both activities were simultaneously eliminated from the sera with a Phl-charcoal adsorbent.

Antibodies↗