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Biomedical subjects

D Geile

Publications and source records attributed to D Geile.

9 recordsLinked to original sources

[Chronic disorders after interventions in the anorectal area--therapeutic possibilities].

Long lasting alterations of anal function and persistent pain in a few patients after ano-rectal operations are a great therapeutic problem. Sometimes more than 6 months after LAR there are complaints about incontinence, disturbance connected to a spastic evacuation--whereas pain is more often connected with the situation after Stapler hemorrhiodectomy or other anal interventions. The therapeutic management has to consider all etiological factors and consists mainly of conservative therapy, including regulation of stool volume, slow-down of colon transit, strengthening of anal and pelvic floor muscles, regulation of co-ordination and ability of relaxation and straining, therapy of pain and--last not least--psychological support.

Anus Diseases↗

[Precancerous conditions and neoplasms of the anal area].

Classification of this lesions could be done concerning localisation and histological type. Squamous cell carcinoma of the anal canal are the most often to be found, but overall neoplasias in this region are very seldom. The most important role in pathogenesis seems to play infection with HPV viruses. Symptoms are in the beginning unspecific and similar to other common proctological diseases. Proctological diagnostic procedures are to be combined with cytological methods. Therapeutic management depends on malignant potential of the lesions and contains local excision, total operation and combined radiochemotherapy, which is today considered standard therapy of squamous cell carcinoma of the anal canal.

Anal Canal↗

[Conservative therapy of incontinence].

Conservative therapy of faecal incontinence includes normalisation of colonic function, restauration of damaged anal skin and exercising methods. The most successful of those seems to be Biofeedback with good short time results up to 92% patients without further complaints, the long time results still being up to 67%. Prognosis depends on neuropathy, age and ability of perception and compliance. Passive electrostimulation replaces the damaged nerve and therefore has to be done lifelong. Increasing anal resting pressure seems to be a possible result.

Aged↗

[Hemorrhoidal disease].

Prevalence of hemorrhoidal diseases in proctologic practice has decreased over the past years. Inflammatory and functional diseases predominant as a consequence of improved differential diagnosis and diagnostic management. In less than 20% of patients of a specialized practice stage-adapted therapy is indicated. Favorable long term results, however, are barely obtainable without elimination of pathogenic factors. If inflammatory and/or functional disorders of the anal region are not eliminated relapses are preprogrammed.

Hemorrhoids↗

[Exfoliative gastric cytology -- quality control (author's transl)].

Results of exfoliative gastric cytology from two periods were compared (779 examinations in the first period, 598 in the second). In 85% of cytological examinations, a histologic diagnosis was available. 64% of histologically verified carcinoma were diagnosed by cytology, too. In the second period the percentage of false positive findings decreased from 4,7% to 1,1% and the rate of suspicious findings from 3,7% to 1,5%. The proportion of carcinomas not detected by cytology increased from 32% to 35%. The rate of correct diagnosis of two contributors remained constant (53% resp. 71%). Improvement of diagnostic accuracy depends upon better technique of yield of material by endoscopists.

Humans↗