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Biomedical subjects

D Gerl

Publications and source records attributed to D Gerl.

At least 19 recordsLinked to original sources
PubMed1980

[Pilot study into habitual abortion (author's transl)].

Endocrinic functional disorders obviously are more relevant than other factors to the aetiology of habitual abortion. Delayed menarche combined with menstrual disorders played a major role among the probands examined by the authors. Diagnosis of habitual abortion should be extended, with the view to elucidating other known causes of abortion for their importance to the situation under review. It is not recommended to start diagnosis as late as after the third abortion. A two-phase programme should rather be applied to women who wish to have children, as early as after two consecutive abortions.

Abortion, Habitual↗
PubMed1978

[Quantitative changes of the cytotrophoblast in underweight and normalweight newborn after risk pregnancy and antepartal therapy (author's transl)].

A histochemical-morphometric method was used to determine at the cytotrophoblast of 73 placentas, changes in the composition of the syncytium and in the Langhans' cell count in underweight and normalweight newborn with or without antepartal maternal therapy in comparison to newborn after uneventful pregnancy. The reduction of the percentage share of mature syncytium when the share of predegenerative and degenerative syncytium is increased, as weil as the increase in the average Langhans' cell count in the placentas of premature infants, hypotrophic and eutrophic infants delivered at term after risk pregnancy, compared with normal controls, is statistically significant. Significant differences in the percentage share of mature syncytium between the placentas of premature infants and hypotrophic infants delivered at term, as well as between placentas of eutrophic infants delivered at term, depending of the nature and severity of the risk, are discussed in connection with the significance of the syncytium for the processes of material transport. No correlation with the Apgar score and the occurrence of the respiratory distress syndrome of newborn, nor with the duration of the first and second stage of lavor with macroscopic placenta peculiarities, have been found. The good correlation between placenta findings and classification characteristics of newborn, and clinical aspects of the course of pregnancy, allows the possibility of diagnostic evaluation. Our results indicat also that the morphological performance must be included in the considerations explaining the success of treatment of placental insufficiency.

Female↗
PubMed1977

[Quantitative alterations to resorption villi of normal human placentae in the course of gestation (author's transl)].

A total of 45 placentae of different gestatory age were used to study, after clinically and anamnestically normal pregnancy and by a morphometric method, the quantitative behavior of individual parts of the placental barrier in the course of gestation. For this, hematoxylin-stained preparations and enzyme-incubated semi-thin sections were used. The increase in the percentage of fetal vascular surface with a simultaneous decrease in the relative percentage of villous surface (when determining the ratio of villous surface surrounded by maternal blood to the fetal vascular surface) up to the 28th week of gestation must be considered an expression of an increase in the capability of function. The simultaneous distinct decrease in the average number of Langhans cells and the reduction of their less differentiated forms in favor of those showing a higher degree of differentiation allow to make the conclusion that around the 28th week of gestation conditions in individual villi are, in general, similar to those prevailing in term placentae between the 37th and 41st weeks of gestation. The results obtained from the basis of quantitative studies of the placentae of premature infants and babies born at term after different gestatory risks.

Cell Differentiation↗
PubMed1975

[Developmental trends in obstetrics at the Leipzig University-Gynecological Hospital since the existence of the German Democratic Republic].

An analysis of development in the obstetrics allows following comments: Peripartal and perinatal mortality shows a significant positive development. Maternal mortality has become very rare. The high percentage of approximately 10% of premature birth has a bad influence on the perinatal mortality. The intranatal mortality compared to ante- and post-natal could be sunk to a great extent. The eclampsia is observed very rarely. The reasons for the good results are to be seen not only in widening of indications of obstetrical operations but also in improvement of solicitude, prophylactical, diagnostical and conservative therapeutic measures.

Female↗
PubMed1975

[Morphometric examinations of placenta in stillbirth].

A total of 10 placentas was examined morphometrically following fetal death in utero. In 8 placentas a reduced fetal vascular surface could be observed. In 2 cases the cause of death could be revealed neither clinically nor patho-anatomically, while morphometric investigations demonstrated considerable restrictions of the vascular surface of the villi. In addition to the usual histological placental diagnostics, the morphometric assessment of placentas is recommended.

Female↗
PubMed1973

[Placenta biopsy].

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Biopsy, Needle↗