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Biomedical subjects

D Gibb

Publications and source records attributed to D Gibb.

49 records · Page 3Linked to original sources
PubMed1989

Premature membrane rupture in pregnancies of less than 34 weeks gestation.

The outcome of pregnancies complicated by premature membrane rupture (PROM) at gestations of less than 34 weeks during a one-year period was reviewed. At presentation, infection was suspected in 12 of the 56 mothers, but confirmed in only three. All non-infected patients were then admitted to the ward and managed expectantly. Despite membrane rupture of up to 3-weeks duration, there were no episodes of proven maternal infection amongst the inpatients. Following delivery, seven babies had positive blood cultures; antenatal infection had been suspected, but not proven, in one case only. Four mothers developed postpartum infection which responded to antibiotic therapy. All mothers with infection, presenting either antenatally or postnatally, delivered within 48 h of membrane rupture and in all infected neonates the duration of membrane rupture was 72 h or less. The occurrence of sepsis was not related to the gestational age at onset of the membrane rupture. We conclude that patients with rupture of the membranes of 72 h duration or longer may be admitted for expectant management, even if presenting early in the second trimester, without an increased risk of infection.

Female↗
PubMed1987

Fetal breathing movements as predictor of favourable pregnancy outcome after oligohydramnios due to membrane rupture in second trimester.

In 11 pregnancies complicated by oligohydramnios due to spontaneous rupture of the membranes in the second trimester of pregnancy fetal breathing movements were assessed regularly by ultrasonographic examinations. In the 6 cases in which fetal breathing movements were detected the babies were liveborn and there was no evidence of pulmonary hypoplasia or the other non-renal features of Potter's syndrome. In the other 5 cases there were no fetal breathing movements. 1 pregnancy was terminated electively, and 1 ended in an intrauterine death; the remaining 3 infants died in the neonatal period. All 5 cases showed necropsy evidence of pulmonary hypoplasia. These findings indicate that premature and prolonged rupture of membranes in the second trimester of pregnancy does not uniformly result in a poor prognosis. They suggest that fetal breathing movements could be used as a predictor of favourable neonatal outcome.

Amniotic Fluid↗
PubMed1987

Maternal oxygen therapy for intrauterine growth retardation.

Humidified oxygen (55%) was administered continuously through a face mask to 5 patients whose pregnancies (4 singleton and 1 twin) were all complicated by severe intrauterine growth retardation, oligohydramnios, high blood-flow impedance in the fetal aorta and umbilical artery, and low mean blood-velocity in the fetal thoracic aorta. All the fetuses were hypoxic and 2 were acidotic. After maternal hyperoxygenation, the fetal pO2 increased to within or near the normal range, and resulted in a sustained increase in the mean blood-velocity in the fetal thoracic aorta. 5 fetuses survived with minimum neonatal morbidity. The effect of maternal hyperoxygenation on the fetal pO2 in such cases may prove to be a useful method of assessing placental function and guiding management.

Adult↗
PubMedDate not supplied

Acute appendicitis complicating pregnancy. A case report.

The first report of acute appendicitis complicating pregnancy in Zambia is presented. The diagnostic problems were differentiation between Urinary tract infection concealed accidental haemorrhage and acute appendicitis. However emergency appendicectomy was performed and the outcome was satisfactory. The patient went into premature labour but normally delivered a 2,100g baby. The literature is reviewed; an increased awareness of this condition in our environment is advocated.

Acute Disease↗