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Biomedical subjects

D Godefroy

Publications and source records attributed to D Godefroy.

52 records · Page 3Linked to original sources
PubMed1981

[Intra-osseus hemorrhagic lesions in congenital afibrinogenemia. A new case (author's transl)].

Congenital afibrinemia is a rare disease, transmitted by an autosomal recessive mode, and due to deficient fibrinogen. Osseous involvement is exceptional, since only 2 cases have been reported. We describe a third case. The roentgenographic features are well limited radiolucent lesions, arising in the medullary space, and slightly expanding. These lesions are related to fibrous cysts, resulting from intraosseous hemorrhages. Spontaneous resolution may occur: the absence of fibrin deposits and blood clot probably favours resorption.

Afibrinogenemia↗
PubMed1981

[Bilateral nephrocalcinosis during the course of a Butler-Albright syndrome, explored by ultrasonography. A case report (author's transl)].

Ultrasonography was employed to explore bilateral nephrocalcinosis in a patient with chronic renal tubular acidosis. Ultrasonographic findings in this affection include multiple intraparenchymatous dense echos in the papillomedullary region with a posterior acoustic shadow cone. Technical artefacts employed to establish diagnosis are discussed.

Acidosis, Renal Tubular↗
PubMed1980

[The posterior arch of the Paget's ivory vertebra. Biopsy of six cases (author's transl)].

The authors report 6 cases of isolated "ivory" vertebra which were confirmed as being due to Paget's disease after trocar biopsy. They analyse the radiological characteristics and find evidence of constant involvement of the posterior arch which shows the classical signs of Paget's disease: bone condensation, increase in size and cortico-medullary de-differentiation.

Adult↗
PubMed1976

[Osseous and pulmonary sarcoidosis in a 12 year old girl. Radiological study (author's transl)].

The authors present a rather rare case of sarcoidosis in a 12 year old child. Boney involvement constitutes the first manifestation of the condition, with micro-cystic radiological appearance of the second phalanges of both third fingers. The chest X-ray demonstrated glandular and parenchymatous involvement. The diagnosis was histologically confirmed by osseous biopsy. The authors compare their case with other previously published cases.

Age Factors↗
PubMed1975

[Post-radiation nephritis. Study of the renal consequences of splenic irradiation for lymphoma].

The authors studied the left kidney consequences of splenic irradiation in 40 patients with lymphomas. The renal work-up performed before irradiation and every six months afterwards includes : blood pressure, biological tests, IVP and 197 Hg Neohydrine renal scan. Computer scan data processing showed a partial disfunction of left kidney in 16 patients with 18 month-follow up. Renal disfunction appeared within 8 to 10 months following spleen irradiation. During that period no clinical or radiological abnormalities were observed.

Aged↗
PubMedDate not supplied

Tension-free cuff repairs with excision of macroscopic tendon lesions and muscular advancement: results in a prospective series with limited fatty muscular degeneration.

Recurrent tears after rotator cuff repairs are frequent. These could be influenced by excessive tension on a degenerated tendinous stump and by fatty degeneration of the cuff muscles. The goal of this study was to evaluate the anatomic and functional results of tension-free cuff repairs with the excision of macroscopic tendon lesions in a series with limited muscular fatty degeneration of the infraspinatus and a global fatty degeneration index of rotator cuff muscles equal to or lower than 2. We studied 27 tears, comprising 13 cases involving both supraspinatus and infraspinatus tears, 13 cases with 3-tendon tears, and 1 case with only a supraspinatus tear. All shoulders were operated on through a transacromial approach easily repaired with 2 titanium screws with washers. To obtain a repair without tension, a single advancement was performed in 20 cases and a double advancement of both the supraspinatus and infraspinatus was done in 7 cases. The shoulders were evaluated clinically preoperatively and postoperatively with the non-weighted Constant score and anatomically with computed arthrotomography scans. The mean age at operation was 59.5 years, and the length of follow-up ranged from 1 to 4 years. Of the cuffs, 23 (85%) were watertight 1 year after surgery. No predictive factor of retear could be found. The functional improvement was statistically significant only for watertight cuffs, with an improvement of the Constant score from 57.8 to 75. The only predictive factor of functional outcome in this watertight group was the preoperative Constant score. Single and double advancements yielded similar functional results regardless of the extent of the initial tear, provided that the cuff was watertight at revision.

Aged↗
PubMedDate not supplied

Flounder health status in the Seine Bay. A multibiomarker study.

The Seine Bay is used as a pilot area to assess the usefulness of monitoring programmes using a suite of biological measurements. These biomarkers included ethoxyresorfin-O-deethylase (EROD) and acetylcholinesterase (AChE) activities, multixenobiotic resistance (MXR) protein expression level assessment and gonad histopathology. Samples of European flounder collected in three sites close to the Seine Estuary in late September 1998 showed that 8% of the males were intersex, i.e. had gonads with both male and female tissues. Another 10% of individuals, identified as male by morphological observation during sampling, showed only female tissues on histological sections. These dramatic changes were associated with different patterns of EROD activity, MXR expression or AChE activity inhibition that might reflect shorter time effects of xenobiotics and constitute a starting point to integrate biological responses for the assessment of the health status of flounder in the Seine Bay.

Acetylcholinesterase↗
PubMedDate not supplied

Lumbar facet joint arthrography with the posterior approach.

Lumbar facet joint (LFJ) arthrography with intraarticular injections of long-acting steroids and local anesthetics is routinely used for therapeutic purposes in selected patients for relief of low back pain. The procedure may also be used for diagnostic reasons to establish the source of such pain. However, because direct access to the LFJ space is not always possible owing to degenerative changes such as osteophytes, another posterior approach has been proposed for LFJ arthrography. With the patient in the prone position, a spinal needle is inserted vertically into the inferior recess of an LFJ with fluoroscopic guidance and the patient under local anesthesia. To facilitate puncture, cushions are placed under the patient's abdomen to flatten normal lumbar lordosis, which enlarges the inferior recess of the LFJ. Use of cushions also results in a decrease in tissue thickness in the patient, thereby improving image quality and decreasing radiation exposure. LFJ arthrography can demonstrate the causative role of facet disease in abnormalities responsible for low back pain or sciatica and can be performed easily and rapidly with this direct posterior approach.

Anesthetics, Local↗
PubMedDate not supplied

[Radioguided puncture-infiltration in the treatment of refractory calcifying periarthritis of shoulders].

Trituration-aspiration-infiltration of calcifications of the shoulder region is a method applied for treatment of intractable calcifying periarthritis. A television screen is used to guide the needle until it is in contact with the calcifications provoking the symptoms. Trituration and aspiration of the calcified lesions is followed by saturation with prolonged released corticoids of 41 shoulders treated, recovery or improvement was noted in 70% after one month, results being rated as excellent in 19 patients followed up for 3 months.

Adrenal Cortex Hormones↗
PubMedDate not supplied

[Bone maturation and osteoarticular lesions in top level sportsmen. Apropos of 105 cases].

At the time of the European Gymnastics Championships (Lyon, 1980), X-rays of the left wrist were taken in 105 high level junior athletes. Most importantly, we found a delay in bone age in 73% of the boys and in 78% of the girls, which is probably related to an unbalanced diet and to repeated micro-trauma to the growing epiphyses. In particular, we observed traumatic lesions at the distal extremity of the radius with considerable frequency (83% of gymnasts). They are sometimes accompanied by cubital lesions and they are due to an increased fragility in the epiphyso-metaphyseal region due to the delay in bone maturation.

Adolescent↗
PubMedDate not supplied

[Opaque arthrography of the elbow. Anatomical and radiological correlations and technical considerations (author's transl)].

More frequent use of opaque radiography of the elbow will require the adoption of a strict technique, adapted to the indication, and methodical interpretation of findings based on sound anatomical knowledge of the anatomy of this complex joint. Various practical suggestions for facilitating this exploration are given, together with anatomical data on the orientation of the articular surfaces and the appearances of the different recesses which directly condition the technique and interpretation of this examination.

Cartilage, Articular↗