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D Gorder

Publications and source records attributed to D Gorder.

3 recordsLinked to original sources

Food group and nutrient intakes at baseline in the Multiple Risk Factor Intervention Trial.

This chapter relates food and nutrient intakes at baseline to other facets of reported dietary behavior, major risk factors, and sociodemographic characteristics of men in the Multiple Risk Factor Intervention Trial. Intakes of total fat (38.4% of energy), saturated fatty acids (14.2%), and dietary cholesterol (492 mg/d) were similar to amounts seen in the first and second National Health and Nutrition Examination Surveys in the 1970s and were generally lower than findings from studies in the 1960s. There were inverse relations between total serum cholesterol and intakes of total fat, saturated and monounsaturated fatty acids, and dietary cholesterol. These paradoxical associations were largely attributable to findings in the 21% of men who reported following a special diet, indicating that use of such a diet increases with severity of hypercholesterolemia. Fat intake was directly related to number of meals per week eaten away from home, and to cigarette smoking. Patterns of food and nutrient intake were similar for men stratified by baseline blood pressure and antihypertensive treatment. Intake of total energy and percentages from various dietary fats decreased with age, as did use of sucrose and caffeine. White men consumed more dairy products than did other ethnic groups, whereas black men consumed more eggs, sugars, and sweets. Asians had the highest intake of cereal foods. Those with more education ate less high-fat meat products, more fruit, and more polyunsaturated oils, but also more high-fat dairy products and less breads and cereals; they also drank more alcohol.

Alcohol Drinking↗

Antibodies to phenolic glycolipid-I during long-term therapy: serial measurements in individual patients.

Levels of IgM antibody to phenolic glycolipid-I (PGL-I) were measured in serum specimens collected over the initial 5 or more years of therapy from 11 leprosy patients. All three patients with paucibacillary disease had undetectable levels of antibody throughout their treatment. The eight patients with multibacillary disease had initially elevated levels which fell quite rapidly with treatment, reaching levels of 10% to 30% of their initial pre-treatment level after 5 years of therapy. The single patient with prolonged therapeutic noncompliance had an increase in antibody level, although clinical or bacteriologic relapse was not documented. These results in individual patients demonstrate that IgM antibody to PGL-I declines rapidly and consistently with treatment in multibacillary patients.

Antibodies, Bacterial↗

Comparison of nutrient calculation systems.

A set of 54 24-hour dietary recalls collected in 1975-1976 from males aged 35-57 years who were participating in a cardiovascular risk factor intervention program was submitted to three different nutrient calculation systems to investigate how much of a difference exists among systems in calculating nutrient intakes. The three computerized systems were of varying levels of sophistication. Among differences found, one system reported 1.4% more calories derived from polyunsaturated fat than the other two. For studies investigating the effects of dietary fat intake, this difference between systems may be important. Other significant group differences were seen for carbohydrate and alcohol. Although mean differences among the three systems were not great, dramatic differences were encountered when evaluating individual recalls. Nutrient intake data obtained from dietary recalls for individuals and for groups for whatever purpose are subject to the bias of the nutrient calculation system used. These biases should be considered when interpreting results, comparing results with other studies, and when developing treatment plans in the clinical setting. Recommendations for enhanced standardization include: 1) thorough descriptions in research reports of the particular system used; 2) exchange of standard menus between systems; 3) enhanced quality control of the coding process; 4) periodic updating of the nutrient data base to accommodate new food products and changes in composition of foods.

Adult↗