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Biomedical subjects

D Gourevitch

Publications and source records attributed to D Gourevitch.

At least 19 recordsLinked to original sources
PubMed1995

[How does the small human monster attain its real nature?].

Is the new-born babe beautiful, is it ugly? When it comes to life, it is, in a way, a monster. It will be the nurse's task to reshape its tender flesh gently, as a potter could do with clay, and to carry it to its real nature and beauty, which are socio-cultural.

History, Ancient↗
PubMed1994

Enigmatic statue.

Explore the source record for details and available documents.

Greek World↗
PubMed1993

An improved method for oesophageal intubation.

The authors describe a method of inserting an Atkinson tube using a flexible upper gastrointestinal endoscope which does not require the use of X-ray screening. A retrospective review of 50 patients intubated by this technique has been undertaken and the results presented. Of the lesions, 40% were squamous cell carcinoma and 40% adenocarcinoma, with 84% being situated in the lower third of the oesophagus; 94% of patients only required one intubation. The two major complications of the procedure are tube displacement and oesophageal leak; a tube displacement rate of 13% was recorded, comparable with other series. Eleven patients (20.8%) were found to have an oesophageal leak, but this resulted in death in only three patients (6%). The reasons for these figures are explained. An operative mortality rate of 12% is comparable with series using other methods. The authors conclude that this method of intubation is as safe as Atkinson's original method but has the advantage that X-ray screening is not required.

Aged↗
PubMed1989

[The Anonymus Londinensis and medicine of South Italy].

Can the five doctors from Southern Italy and Sicily, whose theories are described in the famous Anonymus Londinensis (P. Lond. 137), be said to have belonged to an actual 'school of medicine'? Although this article stops short of such a conclusion, it is indicated that, positioned on the fringe of the West's scientific world, they remained aloof from the new medicine, embodied by Hippocrates.

History, Ancient↗
PubMed1988

Endothelial cell adhesion to vascular prosthetic surfaces.

Improving the long term patency of small diameter prosthetic grafts remains an important but elusive objective in vascular surgery. In pursuit of a non-thrombogenic surface, we have cultured human-adult endothelial cells, examined their adhesive properties and their ability to colonize the inner surface of a Dacron graft. To examine cell adhesion, endothelial cells were labelled with 111In-oxine and inoculated onto prosthetic wells previously prepared with either cold insoluble globulin (CIG), 1% gelatin, alginate or left untreated as a control. At 100 min, mean percentage adhesion to CIG and gelatin precoated wells was 86.0 +/- 9.9% (+/- SD) and 81.6 +/- 2.9% respectively, whereas alginate at 57.5 +/- 7.5% and the control well at 48.3 +/- 9.9% showed significantly less adhesion. Further experiments examined the adhesion of Indiumoxine labelled endothelial cells to Dacron graft (2 cm X 6 mm ID) placed in an in vitro arterial circuit. An immediate loss of approximately 20% of the cells occurred within the first 30 s, whereafter, a stable population were adherent to the graft material. By 102 min, 73.4 +/- 1.8% of cells remained attached when exposed to tissue culture medium, but only 64.1 +/- 6.9% after exposure to blood. Cultured human adult endothelial cells adhere most effectively to prosthetic surfaces precoated with CIG or gelatin, and remain attached following exposure to shear forces.

Alginates↗
PubMed1987

Non-invasive endoscopic technique to assess gastrointestinal perfusion.

Changes in mucosal blood flow may occur in many gastrointestinal disorders, but assessment is impossible without a non-invasive in vivo technique. We have compared endoscopic laser Doppler (LD) with oxygen electrode (OE) measurements in a dog isolated colon preparation, using variable perfusion measured with an electromagnetic flow probe. At maximum flow, LD measurements were made at three sites to compare mucosal with serosal readings. Flow rate was varied (1-38 ml/min) and measurements of microcirculatory flux obtained using LD, and of oxygen tension using a serosal OE. A progressive trend towards increasing flux was demonstrated from caecum to rectum-serosa: 46.8 +/- 18.7 V (caecum), 52.6 +/- 17.9 V (mid-colon) and 61.3 +/- 17.6 V (rectum). A parallel trend was observed in mucosal values: 41.1 +/- 18.2 V (caecum), 45.7 +/- 15.2 V (mid-colon) and 54.1 +/- 15.1 V (rectum). At all sites, serosal and mucosal values were not significantly different (Student's t test). LD serosal values correlated significantly with EM flow (r = 0.544, 0.01 greater than P greater than 0.001). A similar linear correlation was found between OE and EM flow (r = 0.65, P less than 0.001). Oxygen tension measurements varied as expected with microcirculatory flux (r = 0.441, 0.02 greater than P greater than 0.01). Endoscopic LD assessment of colonic microcirculation accurately reflects changes in blood flow.

Animals↗
PubMed1986

Splenic conservation after trauma in children.

In this study, we report on the management of 25 consecutive children with splenic injury. In 23 patients, the spleen was preserved (92 per cent) and two were treated by splenectomy. Five splenic injuries occurred in neonates. Four patients (16 per cent) were treated nonoperatively. We demonstrate that operative splenic conservation is usually possible and is a viable option when diagnostic doubt or logistic difficulties preclude safe nonoperative management. Avoidable operations were performed upon two patients (8 per cent). In four (16 per cent), associated intra-abdominal lesions requiring surgical treatment were encountered. In 60 per cent of the patients, extensive extra-abdominal trauma was present.

Child↗