PubMed Health⌕ Search

Biomedical subjects

D Gräbner

Publications and source records attributed to D Gräbner.

11 recordsLinked to original sources

Millisecond-range time-resolved small-angle x-ray scattering studies of micellar transformations.

The transformation of mixtures of cationic and anionic micelles to vesicles has been studied by time-resolved small-angle x-ray scattering (SAXS). Equimolar amounts of ionic surfactant solutions, the anionic TexaponN70-H and the cationic TTAOH, were mixed by a stopped-flow device. Time-resolved SAXS patterns reveal that within the mixing time (<10 ms) mixed micelles are formed. These globular micelles dissolve within about 400-1000 ms and form monodisperse unilamellar vesicles in a much slower process of 5-100 s duration.

Micelles↗

Empyema after pneumonectomy--empyema window or thoracoplasty?

369 pneumonectomies carried out within the years 1981 to 1988 and their empyema complications form the basis for a retrospective analysis to assess the outcome of treating pneumonectomy cavity empyema by window healing. During the same period 31 empyema after 322 pneumonectomies to treat bronchial carcinoma are investigated in more detail as far as their therapeutic modalities are concerned. 20 patients received a thoracic window. 18 of 31 patients (58%) could be cured, and 9 of these were in the thoracic window group. The hospital mortality of empyema patients after pneumonectomy amounted to 42%. In an historical comparison no progress could be recognized in the treatment of this septic complication.

Bronchial Fistula↗

[Endometriosis externa thoracalis].

The incidence of endometriosis is between eight and 15 percent among sexually mature women, with peaks being in the third and fourth decades of age. External thoracic endometriosis is associated with implantation of endometrial tissue into lung, pleura, bronchial system, and diaphragm. Major indicators symptoms of thoracal endometriosis include haemoptysis, thorax pain, recurrent spontaneous pneumothorax, and haemorrhagic pleural effusion, with all these manifestations being temporally coordinated with menstruation. Bronchoscopy and radiography are used for diagnosis, while surgery, hormonal treatment, and radiotherapy are used for therapeutic action. One patient with systemic endometriosis is reported in greater detail in this paper.

Adult↗

[Generalized endometriosis].

Authors report on a case of generalized endometriosis. A 29 years old patient suffered from a primary amenorrhea by reason of an aplastic uterine cervix and an incomplete vaginal aplasia. Endometriosis has been ascertainable histologically in the uterus, in the left tube, near the gall bladder and in the pleura.

Adult↗

[Bifurcated resection in the surgical treatment of central non-small cell T3 carcinoma].

Reported in this paper is experience obtained since 1978 from surgical removal of the tracheal bifurcation in combination with pneumonectomy in 38 cases. Squamous cell carcinoma centrally growing from the upper lobe was recorded from 24 patients to whom 36 interventions had been applied for bronchial carcinoma. 50 per cent of all operations in conjunction with pneumonectomy were performed on patients in the pT3NOMO stage. The cumulated 3-year survival rate amounted to 37 per cent. Mortality in hospital accounted for 18.4 per cent and was thus clearly higher than what had been recordable from standard techniques in carcinoma surgery. Causes of postoperative deaths included insufficient sutures in three cases, pulmonary embolism in 2, and pneumonia in the contralateral residual lung in another 2. Standardised surgical and anaesthesiological techniques were used. Modifications of resections are discussed.

Adult↗

[Regional metastasis of bronchial cancer and therapeutic consequences. A contribution to the problem of the prognostic effectiveness of lymphadenectomy].

In 1003 patients suffering from bronchial carcinoma the authors examined the type of lymph node spread. Radical lymph nodeectomy takes 30 to 60 minutes more without increasing the survival time, only the rate of regional metastases is diminished. The fate of the patient is dependent on the spread of haemotogenous micrometastases. According to the authors opinion simple extirpation of the regional lymph nodes as an en-bloc-procedure will be sufficient.

Adenocarcinoma↗

[Results of pneumonectomy for bronchial carcinoma].

615 patients suffering from lung cancer underwent pneumonectomy from 1966 to 1975 (standardized operation: 379; radical pneumonectomy: 236). Evidently the rate of postoperative insufficiency of the bronchial stump and pulmonary embolism was on the increase in cases of radical surgery. The postoperative mortality rate (including 30th postoperative day) was double as high in the radical group as in standardized operations. The 5 years survival rate following radical surgery came up to 13.1% (standard group 27%). This justifies radical pneumonectomy because there is no alternative left for the patients afflicted.

Carcinoma, Bronchogenic↗

[Thoracic surgery in patients older than 70 years (author's transl)].

In a total of 10,000 thoracosurgical operations the percentage of patients being older than 70 years amounted to 1.1. Most of these patients underwent surgery for bronchial carcinoma. The postoperative mortality rate in these patients could be lowered to 1.0% (1977/78). 25% of the patients older than 70 years who suffered from lung cancer stage I and II survived for more than 5 years after operation.

Age Factors↗

[Angiofollicular lymph-node hyperplasia (author's transl)].

Four cases of angiofollicular lymph-node hyperplasia (Castleman-Lymphoma) are presented, accidentally discovered. They prefer localisation in mediastinum. Histological characteristics are lymph follicular hyperplasia, vascular-proliferation with endothelium hyperplasia and sometimes hyalinosis of follicular centres. The tumor is of benign significance. Its etiologic remains unknown. For clinic relations it is very important to coordinate this tumor with the differential diagnosis of mediastinal diseases.

Adult↗