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Biomedical subjects

D H Deshpande

Publications and source records attributed to D H Deshpande.

At least 19 recordsLinked to original sources
PubMed1982

"Primary" spinal epidural lymphomas. A clinico-pathological study.

The surgical records at the National Institute of Mental Health and Neurosciences, Bangalore, revealed 75 cases of spinal epidural malignant tumours operated on in a period of 8 years (1972-1980). Of these, 21 cases (30.4%) were labelled as "primary" spinal lymphomas, with no evidence of any systemic lymphomatous deposit anywhere in the body at the time of surgery. An analysis of their clinical behaviour, treatment, histological classification, and prognosis showed that a (majority of the patients had lower limb weakness and localized pain at the site of lesion as the presenting clinical symptom, b) laminectomy with decompression of the tumour followed by radiotherapy was the treatment of choice, c) histologically mixed histiocytic lymphocytic variety of lymphoma was commonest, and d) six survivors had a histiocytic lymphocytic lymphoma, suggesting a better prognosis associated with this type.

Adolescent↗
PubMed1980

Malignant subdural effusion. A case report.

A case of subdural effusion caused by carcinomatous metastatic dural deposits is presented. An attempt is made to explain the possible underlying pathophysiological mechanism of malignant subdural haemorrhagic effusion. Whenever malignant subdural effusion is suspected, biopsy of the membrane and cytological examination of the fluid is imperative for a definite diagnosis.

Carcinoma↗
PubMed1980

Histology of the persistent embryonic veins in arteriovenous malformations of brain.

Arterialized venous channels in the arteriovenous malformations of the brain represent persistent embryonic veins. The configuration of these veins resembles embryonic venous channels. Their microscopic features also resembles those of the foetal cerebral veins. The intimal liming of the persisting embryonic veins suggests the approximate age of the foetus at which the arteriovenous fistual is likely to have occurred.

Adolescent↗
PubMed1980

Cerebral cysticercosis: clinical and pathological observations with emphasis on the encephalitic type.

This paper describes clinical and pathological features in 20 cases of cerebral cysticercosis. Ten of them had clinical features suggestive of occupying lesions. In five patients (4 children and 1 adult) the disease manifested itself with headache, fever, convulsions and rapidly deteriorating level of consciousness. The onset of the disease in these patients was acute, the course short and the outcome fatal. Postmortem examination of their brains revealed cysticercus cellulosae. The pathology and pathogenesis of this rare encephalitic form of neurocysticercosis are discussed.

Adolescent↗
PubMed1980

The central canal of the filum terminale in communicating hydrocephalus.

Lumbar thecoperitoneal shunting was carried out in patients with communicating hydrocephalus due to long-standing tuberculous meningitis. At the time of this surgical procedure, the filum terminale was excised to achieve filum terminostomy. The central canal of the excised filum terminale in seven hydrocephalic children and an equal number from control cases was studied histologically. These observations indicate that the central canal of the filum terminale dilates in communicating hydrocephalus, and the dilatation is proportionate to the lateral ventricular enlargement.

Child↗
PubMed1980

Chronic subdural hematoma in the cerebellopontine angle.

A 32-year-old man had the clinical and radiological features of a mass lesion in the left cerebellopontine angle. Surgical exploration revealed a cyst containing 20 ml of altered blood. Microscopic examination of the cyst wall showed the structure of an organizing hematoma in the subdural space. The patient, on repeated questioning, denied a history of head injury.

Adult↗
PubMed1979

Neuronal ceroid lipofuscinosis: clinical and histochemical observations in 2 cases.

Two cases of neuronal ceroid lipofuscinosis are presented with detailed accounts of the clinical, histopathological and histochemical changes in the brain. In one of them, neurochemical analysis of the brain was found to be essentially normal. Despite the pathological and histochemical similarity in these two cases, the clinical forms were quite distinct. The clinical patterns are attributed to differences in the topography of neuronal involvement. The pathogenesis of this extremely rare form of neurolipidosis is discussed with reference to recent literature.

Brain↗
PubMed1979

Hypertrophic pachymeningitis dorsalis.

A young man developed a paraplegia of relatively sudden onset. A myelogram revealed an obstruction at the T8 level. Laminectomy at T7-9 disclosed a remarkably thick dura mater compressing the spinal cord. Microscopic examination of the dura mater was suggestive of syphilitic granulation tissue. Serum and CSF samples examined for evidence of syphilis were strongly reactive.

Adult↗