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Biomedical subjects

D H Starkey

Publications and source records attributed to D H Starkey.

12 recordsLinked to original sources
PubMed1980

The use of indicators for quality control of sterilizing processes in hospital practice: a review.

The development over the last 100 years of spore preparations to challenge sterilization processes using steam is reviewed briefly, and efforts to standardize such biological indicators (BIs) in the last 30 years are reviewed in more detail. A similar review of BIs for the ethylene oxide processes is presented with discussion of spore test resistances compared to the potential resistances of organisms commonly found as contaminants in the materials being sterilized. The development and need for quick-reading chemical indicators (CIs) that produce color changes only when exposed to moist heat or ethylene oxide plus moisture, as planned, are discussed. It is emphasized that BIs and CIs can only indicate that the sterilization process has worked as planned. They do not indicate that the materials being sterilized are completely sterile.

Cross Infection↗
PubMed1971

Fluctuations in antibiotic resistances of gram-negative rods in one hospital, 1961-70, with comment on kanamycin-neomycin relationships.

Records of the percentages of various types of gram-negative rods resistant to six antibiotics are presented for the years 1961 to 1969 with additional notes on 1970. Gross amounts of each antibiotic used in each of the years are also depicted. Resistance-factor transference does not seem to be an important factor but levels of antibiotic usage do seem to affect the percentages of resistant strains found. In the case of kanamycin, extensive use of neomycin appears to have produced much cross-resistance. Free use of polymyxins does not seem to increase resistant percentages.

Ampicillin↗