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Biomedical subjects

D H Temperton

Publications and source records attributed to D H Temperton.

7 recordsLinked to original sources

Long term safety of fluoroscopically guided selective salpingography and tubal catheterization.

BACKGROUND: The irradiation of the ovaries of reproductive age women during fluoroscopically guided selective salpingography and tubal catheterization has raised concern about the safety of the procedure. In addition to the risk of cancer induction, which exists with the irradiation of all tissues, with the gonads, the induction of hereditary disorders is possible. The objective of this study was to estimate these risks and present them in a clinically meaningful way. METHODS: Retrospective analysis was undertaken of 366 consecutive cases of selective salpingography and tubal catheterization performed at the Birmingham Women's Hospital, UK. The radiation doses of different types of procedure were compared with the background annual radiation dose. The risks of cancer and genetic disorders induction were calculated using conversion coefficients published by the International Commission on Radiological Protection. RESULTS: The radiation dose women were exposed to during selective salpingography and tubal catheterization under fluoroscopic guidance was a fraction of the background annual radiation dose. The excess lifetime risks of cancer and hereditary disorders were in the order of four to 13 and two to six per million procedures respectively. CONCLUSIONS: The long term risks of selective salpingography and tubal catheterization under fluoroscopic guidance are low.

Adult↗

Dose-area product readings for fluoroscopic and plain film examinations, including an analysis of the source of variation for barium enema examinations.

This paper contains the results of an investigation undertaken between 1994 and 1996 using dose-area product (DAP) meters for monitoring radiation doses from six types of simple examinations and seven types of complex examinations. Mean hospital DAP levels have been compared with National Reference Levels (NRL), with most departments producing levels lower than NRLs. DAP readings have allowed the proposal of provisional Reference Levels (RL) to be set for simple and complex examinations. The results were also compared with recently published data from the National Radiological Protection Board (NRPB), highlighting those hospitals which need to make changes in radiographic technique. The study of DAP reference doses also confirms that dose levels for complex investigations are clearly related to technique, in terms of screening time and number of films. Although the use of increased screening tube kilovoltage may be relevant, the overall effect is small. The results suggest that there is still a need to optimize the protocols for these examinations. The use of digital equipment has been shown to have a complex effect on dose, particularly in the case of investigations involving both films and fluoroscopy.

Barium↗

Radiological assessment of a new bone densitometer--the Lunar EXPERT.

Dual energy X-ray absorptiometry (DXA) is one of the most widely used techniques in the management of osteoporosis and other skeletal diseases. Although patient doses from DXA are generally low, it is still necessary to measure them to assess the risk of radiation injury. We report on a study to estimate the effective dose (ED) to patients and staff from a new DXA scanner--the Lunar EXPERT, and make a comparison with a similar study carried out on a Lunar DPX-L. The entrance surface doses were measured to be 895 microGy and 10.25 microGy for the EXPERT and DPX-L, respectively. The EXPERT maximum EDs were calculated to be 74.7 microSv and 44.9 microSv for the anteroposterior (AP) lumbar spine and the proximal femur, respectively. More than 50% reduction in ED could be achieved by using a smaller scanning width. The maximum EDs for the DPX-L were calculated to be 0.21 microSv and 0.15 microSv for the AP lumbar spine and the proximal femur, respectively. The scattered dose rates (ambient dose equivalent) were measured to be less than 2 and less than 1 microSv h-1 at 50 cm and 100 cm, respectively, for the DPX-L, and the equivalent values for the EXPERT were 240 and 64 microSv h-1. Although both the patient dose and scattered dose rates are quite low relative to other radiological examinations, good practice aimed at dose reduction should still be implemented. Whilst protection for the operator is not needed for the DPX-L system, it may be (depending on the size of the room) for the EXPERT system.

Absorptiometry, Photon↗

Influence of dose reduction recommendations on changes in chest radiography techniques.

A previous dosimetric study on chest radiography identified ways to reduce patient entrance surface dose (ESD). This present study was designed to monitor changes that had occurred in the use of applied potential and film-screen sensitivity, after a series of recommendations were issued. The study falls into two parts: (1) an assessment of the impact of the recommendations and (2) what factors were responsible for change. Where changes had occurred, exposure factors were collected for 30 patients per tube and the mean ESD was calculated for each tube. Intercomparison (r = 0.93, p < 0.001) was made between calculated and measured (TLDs) values of mean ESD for 10 X-ray units, to ensure that the calculated values provided accurate estimates of the new mean ESDs. 89% of units previously monitored for patient ESD now use average applied potentials greater than 90 kVp and 51% are using film-screen sensitivities of 400. The mean ESD has been reduced on average by 47%, from 0.15 mGy to 0.08 mGy. It has been estimated that the annual collective dose from diagnostic radiology procedures in 30 hospitals in the West Midlands has been reduced by a value in excess of 40 man Sv. Reasons for change could be attributed to some of the following factors: (a) a knowledge of dose levels in comparison with other centres; (b) personal contact with departments; (c) feedback in terms of results and dose savings and (d) positive encouragement to make changes.

Humans↗

Childhood cancer and paternal exposure to ionizing radiation: a second report from the Oxford Survey of Childhood Cancers.

Paternal occupational data already collected as part of the Oxford Survey of Childhood Cancers have been reviewed. Information on paternal occupation was available for 14,869 children dying from cancer in England, Wales, and Scotland in the period 1953-81 and for an equal number of matched controls. The importance of fathers working, at any time before or after conception of the survey child, in any of the following occupations was assessed: radiologists (clinical), surgeons and anesthetists, veterinary surgeons, dental surgeons, nuclear industry workers, industrial radiographers. There was no indication that preconception employment in any of these occupations was more important than postconception employment with regard to the risks of all childhood cancers or all childhood leukemias. Findings were consistent with neither paternal preconception exposure to external ionizing radiation nor exposure to unsealed sources of radionuclides being an important risk factor for childhood leukemia or for the overall grouping of all childhood cancers.

Case-Control Studies↗