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Biomedical subjects

D Habek

Publications and source records attributed to D Habek.

17 recordsLinked to original sources

Heterotopic trigeminal pregnancy in infertile women after ovulation stimulation and embolisation of a uterine myoma.

Heterotopic pregnancy is a simultaneous occurrence of intra-uterine pregnancy and ectopic pregnancy. The incidence of ectopic pregnancy has increased as a consequence of assisted reproduction and ovulation stimulation agents. In this report, we describe the case of a 34-year-old nulliparous woman who became pregnant after ovulation induction with clomiphene. According to her gynaecologic history, she had embolisation of a uterine myoma. The report presents a case of ectopic and twin intra-uterine pregnancy. After total laparoscopic salpingectomy, she had normal intra-uterine pregnancy.

Adult↗

Tuboovarian abscess mimicking intraligamentar uterine myoma and a intrauterine device: a case report.

A case study is presented of tubo-ovarian abscess (pathohystological-verified actinomycosis) in a 41-year-old woman with an intrauterine device (IUD), which on US was found to be imposed upon an intraligamentary degenerated myoma (pyomyoma). The patient was afebrile, with normal vital functions (diuresis, blood pressure and pulse). Exposure of the abdominal cavity by lower transverse laparotomy performed under general endotracheal anaesthesia revealed slight uterus enlargement with normal left adnexa, whereas right adnexa were not exposed due to the soft tumour in the region of the right ligamentum latum, which displaced the urinary bladder and uterus leftward. The peritoneum fold was incised and deprepared, revealing a tumorous formation imposed onto the myoma or onto the 'cold' tubo-ovarian abscess. Total hysterectomy was then performed. Left adnexa showed a normal finding. Hemalaun-eosin staining of the preparation of the tumour capsule and tumour content showed colonies of threads extending radially to the surrounding tissues (drusen), surrounded by pus corpuscles, polymorphonuclears and macrophages containing lipids (sulfur granules). The patient was free from disease relapse at 2 years after the procedure. Thus, total abdominal hysterectomy and salpingoophorectomy, along with antibiotic therapy, were the definite mode of treatment for pelvic actinomycosis.

Abscess↗

Success of acupuncture and acupressure of the Pc 6 acupoint in the treatment of hyperemesis gravidarum.

OBJECTIVE: The aim of this study was to evaluate the antiemetic effect of acupuncture (AP) and acupressure (APr) of the Pc 6 acupoint in pregnant women with hyperemesis gravidarum (HG). METHODS: A prospective, placebo-controlled trial included 36 pregnant women with HG. Two methods of acupuncture were used: bilateral manual AP of the Pc 6 (Neiguan) acupoint (group 1, n = 10) and bilateral APr of the Pc 6 acupoint (group 2, n = 11); furthermore, superficial intracutaneous placebo AP (group 3, n = 8) and placebo APr (group 4, n = 7) was carried out. RESULTS: Anxiodepressive symptoms occurred in 9 pregnant women with HG from group 1, 8 women from group 2, 7 women from group 3, and 5 women from group 4 (p < 0.001). The average gestation age at the occurrence of HG symptoms and the beginning of treatment was 7 weeks in group 1 and 8 weeks in groups 2, 3, and 4. Four women from group 1 and 7 women from groups 2, 3, an 4 needed intravenous compensation of liquid and electrolytes. The antiemetic metoclopramide was given intravenously to 1 woman from group 1, 2 women from group 2, 6 women from group 3, and 4 women from group 4. Promethazine was given to 1 woman from group 2, 1 woman from group 3, and to 3 women from group 4. The efficiency of the HG treatment with AP of the point Pc 6 was 90%, with APr of the Pc 6 63.6%, with placebo AP 12.5%, and with placebo APr 0%. CONCLUSION: Acupuncture (p < 0.0001) and acupressure (p < 0.1) are effective, nonpharmacologic methods for the treatment of HG.

Acupressure↗

Ruptured interstitial pregnancy Two case reports.

The authors described two cases of the ruptured unrecognized interstitial pregnancy. 32-year-old woman, was admitted for abdominal colics in 17th week of uncontrolled pregnancy. Obstetric finding on admission was normal, while ultrasonography pointed to 17th week of gestation. During the first night of hospitalization, severe abdominal pain, with collapse, tachycardia and hypotension developed. Laparotomy was performed in general endotracheal anesthesia with resuscitation measures, and revealed hematoperitoneum and ruptured right-sided interstitial pregnancy with a dead fetus among the bowels. Abdominal hysterectomy without adnexa was performed. S. J., a 35-year-old tertigravida, six years before, left-sided adnexectomy was performed for perforated tubal pregnancy. 5 weeks before artificial abortion now, ultrasonography revealed a vital fetus biometrically corresponding to the 11th week of gestation. The condition was recognized as an unsuccessful artificial abortion and intact pregnancy. During preoperative preparation the patient lost consciousness and required immediate resuscitation. The abdominal cavity was opened by Pfannenstiel's relaparotomy, and revealed hematoperitoneum with numerous adhesions between the small intestine, sigma, uterus and urinary bladder, and ruptured left-sided interstitial pregnancy. Adhesiolysis was completed, a lesion in the sigma was sutured, and hysterectomy was performed. Exploration of the abdominal cavity revealed a dead fetus among small intestine loops, and an indurated, sharply delineated neoplasia of the head of the pancreas.

Abdominal Pain↗

Using acupuncture to treat premenstrual syndrome.

More than 60% of the women in both groups suffered from premenstrual syndrome (PMS) symptoms, such as anxiety, mastalgia, insomnia, nausea and gastrointestinal disorders, whereas a smaller number of women suffered from phobic disorders, premenstrual headaches and migraines. There were three women from the first group and seven women from the second group who continued the medication treatment with progestins, whereas one woman from the first group and nine women from the second group continued to take fluoxetine. In the first group, nine women stopped having PMS symptoms after two AP treatments, eight women stopped having them after three treatments and one woman stopped having them after four treatments. In four women from the first group and 16 women from the second group, PMS symptoms appeared during the following period (cycle) or continued even after four treatments, so the medication was continued. In the first group, one woman had a smaller subcutaneous hematoma after the AP acupoint Ren 6. There was a statistical and relevant reduction in PMS symptoms with the AP treatments in the first group (P<0.001), whereas their reduction was irrelevant in the placebo AP group (P>0.05). The success rate of AP in treating PMS symptoms was 77.8%, whereas it was 5.9%. in the placebo group. The positive influence of AP in treating PMS symptoms can be ascribed to its effects on the serotoninergic and opioidergic neurotransmission that modulates various psychosomatic functions. The initial positive results of PMS symptoms with a holistic approach are encouraging and AP should be suggested to the patients as a method of treatment.

Acupuncture Therapy↗

Rupture of coliform pyosalpinx in a nine-year old girl.

The authors report on an atypical clinical picture of an acute abdomen syndrome caused by the rupture of an atypically located pyosalpinx in a 9-year old girl.A perforated right-sided pyosalpinx was found at two locations, firmly adhering to a vesicouterine excavation. Right-sided salpingectomy, appendectomy, pelvic cavity lavage and drainage of the Douglas cavity were performed. The pathohistology indicated a perforated pyosalpinx and catarrhal appendicitis. On bacteriological analysis, Escherichia coli was isolated from the vaginal discharge and from the pus collected from the small pelvis.

Appendectomy↗

Modified fetal biophysical profile in the assessment of perinatal outcome.

The aim of the study is the evaluation of variables of the biophysical profile in the assessment of perinatal outcome. The prospective study included 87 pregnant women with singleton pregnancy in the 28th to 42nd week of gestation with clinically and ultrasonically verified fetal growth retardation, where the fetal biophysical profile was assessed antenatally. Through the factor analysis of biophysical profile variables we obtained values indicating the contribution of individual variables to the predictability of perinatal outcome. 70% of the patients were examined in 15 minutes according to the principles of modified biophysical profile. The most sensitive variable of the biophysical profile in the prediction of perinatal outcome was the amniotic fluid volume, followed by fetal breathing movements, non-stress test and fetal movements, while the lowest prediction value was assigned to the fetal tone. The modified biophysical profiles need to be perfected on a larger number of pregnant women, which would advance the predictability of this method in detection of hypoxically endangered fetuses.

Female↗

Treatment of a retained placenta with intraumbilical oxytocin injection.

The aim of the study was to assess the effect of intraumbilical administration of oxytocin in the management of retained placenta. This prospective double-blinded clinical study included 31 mothers with retained placenta. The women were divided into three groups: group 1 (n = 19) was given 20 IU syntocinon in 20 ml 0.9% NaCl saline intraumbilically into the vein (IUV); group 2 (n = 8) received 20 ml 0.9% NaCl saline; and group 3 (n = 4) received 0.2 mg ergometrine IUV in 20 ml 0.9% NaCl saline. Intraumbilical injection was used 30-45 min after delivery, and the distal cord segment was clamped to the umbilical vein.--In group 1, placental expulsion within 60 min of IUV oxytocin injection occurred in 13 (68.4%) women; in group 2, placental expulsion was recorded in one (12.5%) woman, whereas no placental expulsion occurred in group 3 women (p < 0.001). Complications in terms of major hemorrhage were not observed in group 1, whereas a hemorrhage of > 500 ml was recorded in one group 2 and 3 woman each. Febrility developed in one woman, and abdominal pain in two women from each group. Manual lysis of the placenta was performed in seven group 1, seven group 2, and all four group 3 women. IUV oxytocin injection provides a useful and inexpensive non-surgical, non-aggressive, cheap and pharmacological method which should be included in the treatment protocol for retained placenta before turning to the procedure of manual lysis of the placenta.

Adult↗

[Pathography and biography of the Empress Maria Theresa].

The empress and queen Maria Theresa Habsburg-Lorraine (May 13th, 1917-November 29th, 1780) bore sixteen children in the marriage with the emperor Franz I Stepha and was famous as "mother-in-law of Europe". Her brother Leopold died immediately after he was born, her sister Amalia died in the cradle and Maria Ana died of perinatal complications at the birth of a dead infant in 1744. The famous hereditary facial dysmorphia of the "Hasburg jawe" wasn't noticed in Maria Theresa's surviving children. In October of 1738, after giving birth to her daughter Ana, a manual lysis of the placenta was performed due to the retained placenta and postpartal bleeding. In 1741 her daughter Carolina died, and in 1767 her daughter Josepha died of small pox. Her daughter Elizabeth remained deformed by the pock marks, and Maria Christina got a puerperal sepsis, but surprisingly, didn't die. Maria Antoinette ended under a guillotine in France, along with her husband Luis XVI. Maria Theresa's father, Karl VI died of the cholecystopankreatitis and peritonitis, and her husband and co-ruler most probably died of acute coronary incident in August 18th, 1765. After her husband's death she started suffering from depression with steady necrophile obsessions. Maria Theresa suffered from a chronical obstructional pulmonary disease (asthma), rehumatic syndromes, hypertension and anxiodepressive syndromes. In 1767 she had small pox. In November 11th 1780 she caught a cold which grew into a pneumonia with high fever. She died of cardiopulmonal dedompensation preceded by pneumonia and asthma.

Asthma↗

Epidemiologic characteristics of sexually transmitted infection/coinfection with Chlamydia trachomatis and Neisseria gonorrhoeae.

Sexually transmitted infection/coinfection with Chlamydia trachomatis and Neisseria gonorrhoeae is responsible for pelvic inflammatory disease, ectopic pregnancy, infertility, neonatal conjunctivitis, and adhesive perihepatitis. The increase in the rate of chlamydial and gonococcal infection/coinfection has been related to promiscuity, inadequate use of mechanical contraception (condom), early sexual activity, and lack of proper sexual education. Therefore, the need of primary prevention and education of the young population, and introduction of amplification screening tests in the diagnosis of chlamydial infection at least before each intrauterine procedure, in women with mucopurulent discharge and in women below age 25 is emphasized.

Chlamydia Infections↗

[Fetal hypoxia--etiology and pathophysiology of hypoxic damage].

In current perinatology, the prevention of hypoxic damage to the organs, brain in particular, is given special emphasis. The causes of fetal hypoxia include maternal (preuterine), intrauterine, umbilical, placental and fetal causes. Hypoxia and hypoxic lesions occur prenatally in about 80%, and perinatally in 10-20% of cases. Hypoxia/ischemia induce cellular and subcellular responses in the fetal brain. Some of these are membraneous phenomena such as potassium channel activation, enhanced release of excitoxic amino acids aspartate and glutaminate, activation of NMDA receptors, transmembranous calcium ion influx, and membranous lipid peroxidation. Cytosolic events include the formation of free oxygen radicals, release of eicosanoids, prostaglandins, leukotriens and cytokines, enzyme activation, and gene induction.

Female↗

Activities of the 105th Croatian Army Brigade Medical Corps during the 1991-1992 war.

The organization and work of the medical corps of the 105th Croatian Army Brigade from Bjelovar, from October 18, 1991 to September 27, 1992, are presented. The brigade operated on the battlefields in East Slavonia, West Slavonia (Novska), and Posavina. Health care was also provided to the civilians living in the area. On their arrival at the battlefield, all members of the 105th Croatian Army Brigade underwent blood group and Rh factor determination and were vaccinated against tetanus. At the battalion and brigade stations, 4,220 diseased and wounded were examined, and 242 surgical procedures were performed, 189 of them under local and 20 under general anesthesia. Respiratory diseases were most common (27.2%), followed by locomotor (14.5%) and gastrointestinal (11.2%) disease. Wounding was recorded in 5.4% of the total number of patients, with 29.3 and 17.5% referring to explosive and gunshot wounds, respectively. Primary care of war wounds was provided in 42.5% of the patients. Total mortality was 2.2%. Wound infection or lethal outcome was not recorded during the triage, treatment, and evacuation.

Anesthesia↗

[Intact cervical pregnancy].

The authors describe a case of intact cervical pregnancy in a 24-year-old secundigravida. The patient was treated successfully with Methotrexate. Conservative treatment is the first choice in the therapy of uncomplicated cervical pregnancy. Conservative and operative therapeutic procedures are discussed.

Abortifacient Agents, Nonsteroidal↗

[Delivery with the foot and umbilical cord alongside the head].

Compound presentation with a foot and umbilical cord alongside the head at the pelvis outlet in a primipara is described. A live femal newborn, birth weight 2850 g, birth length 49 cm, Apgar score 5/8/9, with normal postnatal development, was born by vaginal delivery.

Adult↗

[Effect of smoking on the feto-placental unit].

Tobacco smoke and its metabolites, especially nicotine, have an irritant, genotoxic, mutagenic, teratogenic, cancerigenic and psychoactive effect. Smoking during pregnancy is considered an antepartal (maternal) cause of fetal hypoxemia, i.e. fetoplacental respiratory insufficiency. Carboxyhemoglobinaemia and chronic hypoxemia, impairment of chorionic histoarchitectonic and placentation, vasoconstriction of uteroplacental circulation and intermediary metabolism disturbance are the etiopathogenetic basis of intrauterine fetal growth retardation, i.e. fetal smoking syndrome.

Female↗