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Biomedical subjects

D Haffajee

Publications and source records attributed to D Haffajee.

8 recordsLinked to original sources

Swanson implant arthroplasty of the wrist in rheumatoid arthritis.

Sixty rheumatoid wrists operated with Swanson implant arthroplasty were evaluated after a mean observation time of thirty-three months. Grip function in daily living improved in 60%, pain decreased in 88%, range of motion increased in 83% and grip strength increased in 69% of operated wrists. Significantly impaired function was found in wrists with implant fracture (12%) and in cases with pronounced bone resorption around the implant (23%). Ulnar deviation and carpal collapse were commonly found but did not impair the function significantly. In seven patients the contralateral wrist had been fused and was compared to the arthroplasty. The merits and indications of arthroplasty are discussed.

Adult↗

Silastic scaphoid implants in osteoarthritis of the radioscaphoid joint.

The long term results of Silastic Scaphoid implants are presented in two groups of patients, with osteoarthritis of the radioscaphoid joint without known history of trauma or established pseudarthrosis of the scaphoid bone. The patients in the former group all became satisfied with the operative result whereas in the latter group only half of the patients were satisfied with the result.

Adult↗

Analysis of vasospasm in hand arteries by in vitro pharmacology, hand angiography and finger plethysmography.

1. The distribution of sympathetic nerves in hand arteries and veins from 18 normal subjects was studied by microscopy according to the Falck-Hillarp histofluorescence method for the cellular visualization of cathecholamines and by quantitative analysis of noradrenaline with a radioenzymatic method. Segments of hand arteries and veins were tested in vitro for the vasomotor effect of sympathomimetic agonists. 2. Fluorescence microscopy revealed a plexus of noradrenaline-containing nerve fibres surrounding both arteries and veins. The concentration of noradrenaline in the walls were 4.5-4.7 ng/mg protein. The relative agonist potency was characteristic for alpha-receptors. Phentolamine produced parallel shift of the dose-response curves both for arteries and veins. 3. Finger plethysmography with local cold provocation down to 10 degrees C was performed in the patients with traumatic vasospastic disease before and after inhibition of the sympathetic nervous system by body warming and orally administered alcohol. Four patients had undisturbed circulation, as revealed by the ratio between the systolic blood pressure in the arm and in the finger in conjunction with cold provocation tests. 13 patients had vasospasm of varying degrees, and 3 patients suffered from organic stenosis. 4. Hand angiography was performed before and after local cold provocation. The patients with organic stenosis did not show vasodilatation after 4-6 mg phentolamine injection. Patients with true vasospasm responded, in addition, with efficient vasodilatation 15 min after reserpine injection, which also abolished the cold-induced vasospasm.

Angiography↗

Endoprosthetic replacement of the trapezium for arthrosis in the carpometacarpal joint of the thumb.

One hundred silicone endoprosthetic replacements of the trapezium for arthrosis of the carpometacarpal joint of the thumb (CMC-1 joint) were reviewed in 79 patients with a follow-up time from one to 5 years in 67 women and 12 men. Pre- and postoperatively, pain, range of abduction of the CMC-1 joint, grip and pinch strength were recorded. Pain was relieved in 95 hands and abduction was improved in 85 hands. Dislocation of the endoprosthesis was found in the 15 hands with unimproved abduction. Grip strength was improved in 82 hands and pinch strength in 72 hands. Hyperextension of the metacarpophalangeal joint treated by fusion when more than 20 degrees before operation gave better function than when not fused. Complications were dislocation of the endoprosthesis in 19 hands, one infection, and two fractures of the metacarpal shaft. No fracture of the endoprosthesis itself was observed.

Aged↗