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Biomedical subjects

D Hale

Publications and source records attributed to D Hale.

At least 19 recordsLinked to original sources
PubMed1995

Evaluation of a commercially available ELISA assay for detection of Giardia lamblia in fecal specimens.

A total of 417 fecal samples preserved in 10% buffered formalin and PVA were submitted to a commercial microbiology laboratory only for the detection of Giardia lamblia. Results from fecal specimens collected from 411 patients with gastrointestinal symptoms were compared using the following methods: (a) standard Ova & Parasite (O&P) concentration; (b) Alexon's ProspecT/Giardia enzyme-linked immunosorbent assay (ELISA) test, and (c) Meridian's Direct Fluorescent Antibody (DFA) Stain. In the 29 specimens in which G. lamblia was detected, 10 were O&P, DFA and ELISA positive, 17 were only ELISA positive and two were only Ova & Parasite and Direct Fluorescent Antibody positive. Of the 29 positive specimens, 22 were confirmed as true positives. The ELISA sensitivity was 91% and the specificity was 98%. The expense associated with these methods to detect the presence of Giardia is $11.00, $8.95, and $12.80, respectively. In symptomatic patients, the ProspecT/Giardia ELISA is a cost-effective, rapid, and sensitive method for detecting the presence of G. lamblia in fecal specimens.

Animals↗
PubMed1992

Use of Hemo-De to eliminate toxic agents used for concentration and trichrome staining of intestinal parasites.

In a blind comparison, 465 randomly collected clinical fecal specimens were examined. Hemo-De was found to be an excellent replacement for ethyl acetate in the concentration procedure and for carbol-xylene and xylene in the trichrome staining procedure. Elimination of toxic reagents, combined with its lower cost, makes Hemo-De the preferred choice in routine parasitology examinations.

Acetates↗
PubMed1991

Primary cardiac valve tumors.

To investigate the characteristics of primary cardiac valve tumors, we retrospectively analyzed our multiinstitutional experience from 1932 through 1990. We encountered 56 valvular tumors in 53 patients. The average age of these patients was 52 years (range, 2 to 88 years) and 79% (42/53) were male. Symptoms were present in 38% (20/53) and were neurological in 15% (8/53). Four patients experienced sudden death. Each of the four valves was affected with approximately equal frequency: 16 aortic, 15 mitral, 13 pulmonary, and 12 tricuspid. All but four tumors were benign. The most common histological type was papillary fibroelastoma (41), followed by myxomas (5), fibromas (4), sarcomas (2), hamartoma (1), hemangioma (1), histiocytoma (1), and undifferentiated (1). Average tumor size was 1.15 cm (range, 3 mm to 7 cm), and the average size of fibroelastomas was 8 mm (range, 3 to 15 mm). Mitral valve tumors were more likely than aortic valve tumors to produce serious neurological symptoms or sudden death (8/15 versus 3/16; p less than 0.05). Six patients underwent echocardiography, and results were positive in each. All 6 underwent uncomplicated valve repair or replacement. Compared with a series of 407 nonvalvular tumors, cardiac valve tumors are more likely to occur in male patients (p less than 0.001) and adults (p less than 0.001). Valve tumors are also more commonly benign (p less than 0.001) and asymptomatic (p less than 0.001). These tumors demonstrate somewhat less aggressive behavior compared with non-valvular tumors, but their distinct propensity to produce serious clinical sequelae argues in favor of surgical resection for all cardiac valve tumors.

Female↗
PubMed1990

Incidence of anatomic variants in Guyon's canal.

This study was undertaken to determine the frequency of variations involving the anatomy of Guyon's canal. A series of 58 wrist dissections revealed a 22.4% incidence of anomalous muscles and a 1.7% incidence of anomalous nerve paths. The relationship of the deep branch of the ulnar artery to the superficial and deep branches of the ulnar nerve was found to vary. Accessory muscles passing through Guyon's canal are common, and are often found bilaterally. Aberrant branching of the ulnar nerve in this area is rare.

Humans↗
PubMed1987

Taking time out.

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Dentists↗
PubMed1986

From there to here.

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Dental Equipment↗
PubMed1985

Inspection time and intelligence in dyslexic children.

Dyslexics and normal readers aged 9-11 were compared on an inspection time task. Results indicated that dyslexics required significantly longer inspection times. The findings suggested, however, that there was greater individual variation among dyslexics than among normal readers and that the dyslexics benefited from practice to a considerable extent. Inspection times were not significantly related to IQ as measured by a non-verbal test.

Attention↗
PubMed1984

A path to success.

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Dental Health Services↗