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Biomedical subjects

D Hatch

Publications and source records attributed to D Hatch.

24 records · Page 2Linked to original sources

Treatment of bacterial meningitis with ceftazidime.

Ceftazidime was prospectively evaluated in the treatment of bacterial meningitis in 19 pediatric patients. Haemophilus influenzae type b (HIB) was the etiologic agent in 17 patients, and Streptococcus pneumonia and Neisseria meningitidis were the etiologic agents in one patient each. Ceftazidime was administered intravenously in a dosage of 150 mg/kg/day divided into eight hourly doses for a mean of 15 days (range, 14 to 22 days) for H. influenzae type b meningitis. The clinical and microbiologic response was appropriate in all cases. The mean ceftazidime CSF concentration was 6.7 micrograms/ml at approximately 2 hours following iv infusions. This concentration was 16- to greater than 100-fold the minimal bactericidal concentration determined for the isolated pathogens. These preliminary observations support ceftazidime as a candidate cephalosporin for the treatment of bacterial meningitis caused by H. influenzae. Additional study is required to further define its role in meningitis caused by S. pneumoniae and N. meningitidis.

Adolescent↗

Evaluating postoperative cataract patients using the Kowa Flare Cell Meter.

The estimation of flare and cell in the anterior chamber is an important part of the postoperative care of patients who have had cataract surgery. The Kowa Flare Cell Meter uses a laser beam for a probe of light, lines it up precisely in a specially modified slit lamp, and controls and measures the results with a computer. The Kowa Flow Cell Meter incorporates a computer for input of demographics and a screen display and printer for output of the results. The anterior chamber findings are displayed both numerically and graphically.

Cataract↗