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D Haumont

Publications and source records attributed to D Haumont.

33 records · Page 2Linked to original sources
PubMed1982

[Glycosylated hemoglobin and clinical evaluation of the degree of diabetes control. Relation to blood sugar, blood cholesterol, blood triglycerides, and the duration of diabetes and retinopathy. Study of 85 diabetic children and adolescents].

The measurement of HbA1 gives an "objective" estimate of the degree of metabolic control of diabetes during the erythrocyte lifespan. 333 assays in 85 young diabetics aged three to twenty-three years showed a mean HbA1 of 10.9 +/- 2.6% (controls: 7.4 +/- 1.4%). HbA1 levels parallel the clinical evaluation of the degree of control. HbA1 concentrations are correlated with the duration of diabetes (r = 0.26; p less than 0.001), triglyceridemia (r = 0.22; p less than 0.001), cholesterolemia (r = 0.26; p less than 0.001) and glycemia (r = 0.50; p less than 0.001). The HbA1 glycemia correlation grows stronger as glycemia increases. This probably reflects the existence of a labile form of HbA1. HbA1 concentrations measured repeatedly over one year were not significantly different in diabetics with and without retinopathy, probably because the study period was too short. Measurement of HbA1 is also of value in diagnosing non-compliance.

Adolescent↗
PubMed1982

Exogenous insulin needs. Relationship with duration of diabetes, C-peptidemia, insulin antibodies, and retinopathy.

The study included 75 young diabetics, having a mean age of 13.7 (+/- 3.4) years, and whose diabetes duration was 5.0 (+/- 3.1) years. All of the subjects were insulin dependent, and none had developed insulin resistance. Injections of either conventional or purified insulin were used. The subjects' diets were "spontaneously balanced", and their physical exercise was similar to non-diabetic school-age children. The 75 diabetics were arbitrarily divided into two groups, A and B, according to their average insulin dose/kg, either less than 1 U/kg or greater than 1 U/kg. Groups A and B were comparable according to their age, age of diabetic onset, degree of diabetic control, frequency of retinal complications, proportion of different insulin types, and concentration of beef or pork insulin antibodies. Insulin antibodies were therefore not responsible for any modification in insulin needs. Insulin needs per kg were very significantly correlated to residual secretion of endogenous insulin (r = -0.34; p less than 0.001). They were equally dependent on the duration of diabetes probably because of the progressive beta cell exhaustion. Insulin needs were also weakly negatively correlated to weight, therefore the heaviest diabetics injected an insulin/kg dose relatively less than the lighter diabetics.

Adolescent↗
PubMed1982

[Residual insulin secretion in juvenile diabetes. Relationships with duration of diabetes, metabolic control and retinopathy (author's transl)].

This study concerned 74 diabetic children and adolescents, ages ranging from 3 to 21 years. Duration of the disease ranged from 1 month to 15 years. Blood samples were taken during a 12 month period of observation. 292 immunoreactive C-peptide (CPR) evaluations showed a residual endogeneous secretion of insulin in 57% of cases. CPR and duration of diabetes were negatively correlated (r = -0.35; p less than 0.01); however, even 5 years after onset of the disease, a residual beta-cell activity could be observed. CPR was not related with blood glucose, triglyceride, cholesterol or glycosylated hemoglobin levels. On the other hand, CPR was statistically higher in patients whose diabetes had been well-controlled from the onset of the disease, according to clinical criteria, and in those who did not present with retinopathy: however they were also the patients with the shortest duration of disease.

Adolescent↗
PubMed1979

EEG abnormalities in diabetic children: influence of hypoglycemia and vascular complications.

The effect of diabetic control upon EEG has seldom been studied. In the present investigation, a significant positive correlation between EEG abnormalities and degree of diabetic control was found, but no definite increase was noted in relation to the duration of diabetes. Eighty per cent of our patients having more than 5 severe hypoglycemic attacks showed evidence of abnormal EEG, suggesting that hypoglycemic coma or convulsions are closely related to EEG abnormalities (minor hypoglycemic episodes had no effect on the EEG). With the sensitive technique of fluorescein angiography, we demonstrated a clear correlation between incipient retinal angiopathy and EEG abnormalities. The factors that most positively relate to pathologic electrocerebral (EEG) activity in diabetic children are frequent and severe hypoglycemic attacks, comas and/or convulsions, and vascular changes in the retina.

Adolescent↗
PubMedDate not supplied

[Obstetrical and perinatal outcome of patients not covered by medical insurance].

The number of pregnant women uncovered by medical insurance is increasing in the maternity of Saint-Pierre Hospital (44% increase over a 3 year period). During the academic year 92-93, this situation was present in 9.8% of the mothers; 98% of these patients were foreigners. The majority of pregnancies were not or poorly followed. Admissions occurred very often in emergency situations. The lack of prenatal care in this population with a very low socio-economic level led to a six-fold increase in perinatal mortality after exclusion of congenital malformations (58.4% versus 8.7%). This high mortality rate was mainly due to extreme prematurity (birthweight between 500 and 1500 g).

Belgium↗