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Biomedical subjects

D Haviv

Publications and source records attributed to D Haviv.

9 recordsLinked to original sources

Excimer laser photoastigmatic refractive keratectomy: eighteen-month follow-up.

OBJECTIVE: To study the efficacy of photoastigmatic refractive keratectomy (PARK) by the MEL 60 (Aesculap-Meditec, Jana, Germany) scanning excimer laser for the treatment of myopic astigmatism, with follow-up of 18 months. PATIENTS AND METHODS: One hundred and twenty-eight eyes of 102 patients with different degrees of myopic astigmatism were treated by PARK and followed prospectively in an open study. Ablations were performed with an MEL 60 excimer laser using an astigmatic module. RESULTS: Mean preoperative refractive cylinder improved from a preoperative value of -1.8 +/- 0.8 diopters (D; range, -1.0 to -6.0 D) to -0.3 +/- 0.5 D (range, +1.0 to -2.5 D) at 18 months. The mean reduction in cylindrical correction alone was 84 +/- 37% in the low astigmatism group (-1.0 to -1.5 D); 91 +/- 21% in the moderate astigmatism group (-1.75 to -2.5 D); and 75 +/- 25% in the high astigmatism group (-2.75 to -6.0 D). One hundred and three eyes (80%) at 12 months and 100 eyes (85%) at 18 months were within +/-0.5 D of the intended astigmatic correction, with more eyes in the low astigmatic group. One hundred and nineteen eyes (93%) and 114 eyes (97%) at 12 and 18 months, respectively, were within +/-1.0 D of the intended correction. Ninety-two percent to 95.7% of the eyes in the different groups had a postoperative axis less than 10 degrees of the preoperative and intended axis at 12 and 18 months after PARK. Uncorrected visual acuity (UCVA) of 20/40 or better was achieved in nearly 84% of the eyes 12 and 18 months after PARK. A UCVA of 20/20 was achieved in 49% of eyes 18 months after PARK. Ten eyes (8%) underwent reoperation at the end of 12 months. CONCLUSIONS: The data indicate that PARK is an effective surgical tool for correcting astigmatism, especially astigmatism of 1.0 to -2.5 D, with a success rate of approximately 70%.

Adolescent↗

Excimer laser phototherapeutic keratectomy for recurrent corneal erosion.

PURPOSE: To evaluate the outcome of excimer laser phototherapeutic keratectomy (PTK) for recurrent corneal erosion. SETTING: Laser Institute, Assay Harofeh Medical Center, Zerifin, Israel. METHODS: Twenty-three patients with a mean age of 50.56 years +/- 13.87 (SD) were referred between 1991 and 1995 for recurrent corneal erosion that did not respond to conservative treatment. All were treated by excimer laser PTK. Patients were interviewed and examined before and after treatment. RESULTS: Disease duration ranged from 2 months to 10 years. Frequency of attacks ranged from weekly to three to four times a year. Re-epithelialization of the cornea was established within an average of 3 days after PTK treatment. Follow-up was 12 to 60 months (mean 38.43 +/- 12.08 months). Nineteen (83%) patients were free of recurrences, and 3 had one recurrence treated successfully by patching. One patient who had two recurrences had a second PTK procedure and was symptom free for 14 months. No patient reported reduced visual acuity or quality. Postoperative best corrected visual acuity was unaltered in 21 eyes and improved in 2. There was no significant difference between preoperative and postoperative manifest refractions. CONCLUSION: Excimer laser PRK appears to be a safe and effective treatment for recurrent erosions of the cornea.

Adult↗

[Laser photorefractive surgery].

As photorefractive keratectomy (PRK) with excimer laser gains world-wide acceptance, more patients are able to discard their spectacles. Our study comprised 611 eyes which underwent PRK and were followed for at least a year. Those with myopia up to -6.00D had better post-operative visual acuity and refraction, than patients with higher grades of myopia. They had less corneal haze and a greater proportion were satisfied with their results. Complaints of halos and glare were similar at all degrees of myopia up to -10.00D.

Follow-Up Studies↗

For how long can regression continue after photorefractive keratectomy for myopia?

PURPOSE: The presence and degree of regression were assessed from 18 to 30 months after photorefractive keratectomy (PRK). METHODS: A total of 449 eyes (449 patients) were treated with an Aesculap Meditec 193-nm Arf Excimer laser. These 449 eyes were followed during the first 24 months after PRK, and 252 of these eyes were followed for 24 to 30 months. RESULTS: Thirty (6.7%) of the 449 eyes followed for up to 24 months showed good refractive results during the first year and a half but regressed thereafter and required retreatment. Late regression was confined to subjects with pretreatment myopia above -4.0 diopters (D) and was the same in low- and high-myopic eyes between 18 and 24 months post-PRK. However, between 24 and 30 months, regression was higher in low-myopic eyes, where it reached -0.55 D, than in high-myopic eyes, where it was -0.21 D. This lower frequency of regression in high-myopic eyes is attributed to the relatively high rate of retreatment in this group during the first 18 months after PRK. CONCLUSIONS: Although the findings indicate a fairly low rate of regression after 24 months, there still are insufficient data on which to predict when regression post-PRK stabilizes.

Adult↗

Influence of patient age on refraction and corneal haze after photorefractive keratectomy.

AIMS/BACKGROUND: Since wound healing processes are known to be more rapid in those who are young, it was decided to examine the effect of patient age on refractive outcome of photorefractive keratectomy (PRK). METHODS: The records of 599 eyes that had undergone PRK were studied retrospectively. The eyes were categorised by baseline myopia and patient age. Spherical equivalent and corneal haze were compared in the baseline refraction and age groups at 3, 6, and 12 months after PRK. RESULTS: There were no differences in postoperative refraction and corneal haze in the different age groups. CONCLUSION: Patient age had no statistically significant effect on refraction and corneal haze 1 year after PRK.

Adult↗

Results of a repeated excimer laser photorefractive keratectomy for myopia.

BACKGROUND AND OBJECTIVE: As photorefractive keratectomy (PRK) becomes more widely used, the incidence of repeated PRK increases. The present study was conducted to evaluate results of repeated PRK in view of the meager data on this topic. PATIENTS AND METHODS: In this retrospective study, the authors reviewed the records of 1028 eyes that had undergone PRK, and analyzed the results of 66 eyes that required a second PRK for undercorrection according to baseline refraction. RESULTS: A second PRK was performed in 6.3%, 13.7%, and 10.1% of low, moderate, and high myopes, respectively. The mean refraction 1 year after repeated PRK was similar in both myopic groups: less than -1.00 D. Of the low myopes, 87.50% had residual refraction within 1 D after 1 year. Of the moderate myopes, 88.23% had residual refraction within 1 D after 1 year. All of the low myopes achieved uncorrected visual acuity (VA) of 20/25 or better 1 year after repeated PRK, compared with 58.82% of the moderate myopes. Loss of best-corrected VA never exceeded two lines. CONCLUSION: The overall results of PRK appear to be satisfactory.

Adult↗

[Excimer laser photorefractive keratectomy for myopia].

We have used excimer laser during the past year to correct refractive errors (myopia and hypermetropia) and to remove superficial corneal scars. 714 eyes underwent excimer laser photorefractive keratectomy for correction of myopia and 81% of the patients achieved uncorrected visual acuity of 6/12 or better without glasses. 17 patients underwent a second treatment to correct residual myopia and all of them had uncorrected visual acuity of 6/12 or better 6 months later. The results show that excimer laser photorefractive keratectomy is a safe and efficient procedure to correct myopia. The possibility of various postoperative complications appearing over the long term suggests cautious optimism.

Cornea↗

Immunohistochemical diagnosis of a totally necrotic retinoblastoma: a clinicopathologic case.

An 8-month-old girl underwent enucleation of her right eye because of a calcified retrolental white mass filling the entire vitreous cavity. The conventional histological examination revealed a totally necrotic unidentifiable tumor, with scattered foci of calcification. In addition, we found two islands of viable small round cells, suspected to be retinoblastoma cells, which were located in the optic nerve behind the lamina cribrosa. These cells stained positively for neuron-specific enolase (NSE), but not for glial-fibrillary-acidic-protein (GFAP), supporting the diagnosis of retinoblastoma. Because one of the latter foci of viable tumor cells was located at the cut end of the optic nerve, the baby was treated by external beam irradiation.

Eye Neoplasms↗