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Biomedical subjects

D Hell

Publications and source records attributed to D Hell.

At least 73 records · Page 4Linked to original sources

[Clinic discharge of schizophrenic patients: treatment termination or transition? A catamnestic study of community psychiatric management].

In order to evaluate which single or combined factors can lead to best acceptance of continuing out-patient psychiatric care, a random sample of 73 patients diagnosed as schizophrenic were entered into a follow-up study on leaving a psychiatric hospital. In a given region with only one public mental health center it was found that early and comprehensive planning of hospital dismissal, cooperation of family and--where possible--no change of the responsible therapist led to a 84% rate of patients remaining in the regional psychiatric care system, with a rehospitalisation rate of 33% within a year. Literature on the subject is reviewed in perspective of the rather high acceptance of psychiatric aftercare and the rather low rate of rehospitalisation.

Activities of Daily Living↗

[Cognitive deficits, vitamin status and controlled thiamine substitution in alcohol dependent patients in withdrawal treatment].

Vitamin status and cognitive performance in a test battery were analyzed in 45 alcohol dependent men after admission to and after two weeks of withdrawal treatment in two psychiatric clinics. To examine the effect of thiamin substitution versus alcohol withdrawal and hospital diet alone, 23 patients received 300 mg thiamin daily, 22 patients no vitamin substitution. Thiamin substitution alone ameliorated selectively and significantly the mean marginal thiamin status. Multiple correlations between measurements of the thiamin parameter transketolase activity and test performances were found in the total study group. Thiamin substitution decreased the percentage of weak test performances, whereas the mean test performances did not differ significantly between experimental and control groups (limited in numbers). For clinical practice, thiamin substitution seems indicated during stationary withdrawal treatments, because there is no amelioration of the thiamin status with hospital diet and alcohol withdrawal alone, but there are possible correlations of thiamin deficiency and cognitive performances.

Adult↗

[Malignant neuroleptic syndrome. Literature review and case report].

The neuroleptic malignant syndrome, first described by Delay and Deniker in 1968, is a rare but severe complication of neuroleptic treatment. According to the literature the syndrome particularly affects young men undergoing rapidly intensified neuroleptic treatment ("rapid neuroleptization"). The diagnosis is based on the triad of hyperthermia, extrapyramidal signs, and autonomic dysfunction, once infectious disease has been ruled out. The clinical features, course and therapy of the syndrome are described on the basis of a case report.

Adult↗

[The course of schizophrenia in continued marriage and loss of the partner].

A sample representative of 52 schizophrenic patients has been studied five years after the first control. The patients with enduring relationships show a more favorable prognostic than those with a history of separation, divorce or loss of partner--especially concerning the social and professional skills. The enduring partnership is mostly evaluated by the patients as satisfactory even after repeated hospitalisations.

Adult↗

[Psycho-organic syndrome in drug addicts and alcoholics].

Organic brain syndromes in alcoholics can be observed on three different levels (subclinical impairment of mental skills, amnestic syndrome und dementia, neuropsychiatric disturbances). Subclinical psychological deficits depend on amount and duration of alcohol abuse, length of the withdrawal period and age of alcoholics. Amnestic syndrome and dementia disturbances are well-known in the Wernicke-Korsakoff-syndrome. In a survey of literature the actual knowledge about these different deficiency-syndromes is summarized.

Alcohol Amnestic Disorder↗

The spouses of depressive and schizophrenic patients. A controlled study.

The personality structures and the well-being of the partners of a representative sample of 103 married depressive or schizophrenic hospitalised patients were examined. As a means of examination we used a semi-structured interview, the Giessen-test (Beckmann and Richter 1972, 1979) and the Eigenschaftswörterliste (Janke and Debus 1978). Concerning personality, the comparison of self-image of the partners with the patient's estimation of his or her spouse resulted in good mutual agreement. The spouses of schizophrenic and depressive patients differed neither as far as the average profiles were concerned nor according to the cluster-analysis findings. In addition to this, both groups differed only to a minor extent from a representative sample of the general population. Whereas personal attitude and the well-being of the marital partners were for the most part independent of the depressive or schizophrenic kind of illness, personality and well-being of the spouses correlated with the course of the illness. The more phases of illness the spouses had witnessed, the more unattractive, self-controlled and uncommunicative they proved to be and the less irritated and sensitive they were when the patient was hospitalised. These findings are discussed in the light of further research.

Adult↗

[Thiamine, riboflavine and pyridoxine supply in chronic alcoholism (author's transl)].

Tests on 50 chronic alcoholics demonstrated that there was a reduced supply of thiamine (measured with the transketolase activation test) and riboflavine (glutathione reductase test) compared with results obtained in 1152 healthy controls. A high risk of thiamine deficiency was present in 45.4% of male and 50% of female alcoholics; risk of riboflavine deficiency was 11.1% and 16.7%, respectively. Corresponding results in the normal controls were 2% for thiamine and 0.4% for riboflavine deficiency. There was a significant relationship between enzymatic values of thiamine deficiency, on the one hand, and anaemia, abnormal liver functions (bilirubin, gamma-globulin) and low diastolic arterial pressure, on the other. Enzymatic riboflavine values also correlated with haemoglobin content, so that it is assumed that the anaemia is associated with the reduced thiamine or riboflavine supply. Enzymatic determination of pyridoxine with the GOT activation test would seem to be influenced by alcohol or by metabolic processes induced by it and is therefore not suitable in the presence of chronic alcoholism.

Adolescent↗

[Scocial deviance and drug consumption (author's transl)].

On the basis of epidemiological and psychometric studies we have persued the question how social deviation and drug-consumption could cohere. According to our research the danger of a social deviation (drop out) is the greater the earlier the juveniles begin to take drugs, the more deranged are their original surroundings and the further advanced towards polytoxicomania is their drug abuse. The frequency of drug-consumption corresponds with the number of personal (especially interpersonal) conflicts. In an examination of 4082 20-year-old Swiss men (recruits) 80.2% of the drug-users admitted to have personal difficulties compared to 48.1% of those who take no drgus. 61.2% of the drug-consumers complained about psychic and somatic ailments compared to 33.8% of the drug-abstainers. Youngest and single children consumed drugs significantly more often than elder and eldest brothers and sisters (p less than 0.01). Socio- and psychodynamic backgrounds of the social deviation of drug-consumers are discussed.

Adolescent↗