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Biomedical subjects

D Henrich

Publications and source records attributed to D Henrich.

3 recordsLinked to original sources

Fast inversion recovery T1 contrast and chemical shift contrast in high-resolution snapshot FLASH MR images.

Fast MR imaging attracts the interest of both clinicians and physicists because new diagnostic information arises with reduced artifacts due to short investigational times. With the acceleration of the Snapshot FLASH MR sequence, the measurement of high-resolution images with 256 x 256 matrix is reported, together with contrasting prepulses that are applied to attain contrast in combination with higher in-plane resolution. Measuring times are in the range of a second. For whole-body imaging, a TR = 5.2 msec and a TE = 2.6 msec could be attained measuring omit 256 x 256 matrix images. Artifact-free images demonstrating T1 contrast and contrast from chemical shift are performed on moving organs (heart, intestine) in different experiments. These applications can easily be performed in a couple of minutes for clinical use. Especially in the lung, short TE and high resolution result in a new imaging quality of pulmonary and mediastinal vessels.

Abdomen

Investigation into the effects of cell wall antigens of gram-positive bacteria on lymphocyte stimulation and on cell-mediated cytotoxicity.

The effect of Staph, epidermidis and Bac. subtilis cell walls as well as of cell wall teichoic acid, N-acetyl-muramic acid, N-acetyl-D-glucosamine, D-alanine, and DL-alpha, epsilon-diaminopimelic acid on lymphocyte stimulation and on cell-mediated cytotoxicity has been studied. Bac. subtilis cell wall preparations, N-acetyl-D-glucosamine and teichoic acid showed a slight but significant effect on the mitogenic response of pig lymphocyte cultures. When studied in combination with the mitogens PHA, ConA, and PWM significant synergistic effects were observed with N-acetyl-muramic acid. The most significant stimulation of the in vitro 51Cr-release from labelled P815 tumor cells in the presence of non-sensitized as well as specifically sensitized lymphocytes was exerted by D-alanine.

Animals