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D Hide

Publications and source records attributed to D Hide.

5 recordsLinked to original sources

Hydrolysed protein formulas: thoughts from the Isle of Wight meeting.

The meeting held on the Isle of Wight on 3 March 1995 was organised to discuss some of the recent evidence concerning the use of hydrolysed milk formulas not only in the treatment of cow's milk allergy but also in programmes designed to reduce or prevent other atopic disease. These products and their prophylactic use in particular have generated an amount of controversy firstly when they were introduced as a starting formula in the United States and secondly in Europe where paediatric, allergy and nutrition groups have issued various statements on their use (ESPGAN, 1993; Bjorksten, 1994; ESPACI, 1993; Bindels & Boerma, 1994). The Isle of Wight meeting did not attempt to produce a concensus statement. Nor is this paper an attempt to summarise or bring together the views expressed. Rather it reflects the views of the authors tempered by experience and the evidence presented at the meeting. Seven questions are explored.

Humans↗

Sodium cromoglycate via inhaler and Autohaler.

One hundred and eighty-one children with asthma were entered into a randomized, controlled, crossover study comparing sodium cromoglycate via a metered dose inhaler (MDI) and a breath-actuated inhaler (Autohaler). There were no significant differences in pulmonary function tests (FEV1, FVC, PFER), symptom scores and bronchodilator use between the two devices. However both patients' and clinicians' opinions of sodium cromoglycate effectiveness were significantly better (P < 0.01) for the Autohaler. Autohaler was also thought to be easier to use (P < 0.001) and better for co-ordination of actuation with inhalation (P < 0.001). The Autohaler is as efficacious as the metered dose inhaler used by good co-ordinators. It seems to be the significantly better device with respect to ease of use, actuation and co-ordination which may aid compliance.

Adolescent↗