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Biomedical subjects

D I Reĭngardene

Publications and source records attributed to D I Reĭngardene.

At least 19 recordsLinked to original sources
PubMed2006

[Amiodaron effects on atrioventricular conduction].

AIM: To assess short- and long-term effects of amiodaron on atrioventricular conduction (AVC) of the heart. MATERIAL AND METHODS: Amiodaron was given to 477 patients (mean age 48.7 +/- 0.7 years) with various arrhythmias caused, as a rule by coronary heart disease. A mean saturation dose was 809.4 +/- 13.4 mg/day, a mean maintanence dose--263.5 +/- 5.4 mg/day. Mean follow-up 20.85 +/- 1.2 months. The frequency of AVC disorders was estimated at regular Holter monitoring. RESULTS: In saturation, atrioventricular block of the first degree arose in 17.2% patients, of the second and third degree--only in one patient. AVC disorders disappeared at reduction of amiodaron dose. Only in one patient the drug was discontinued because of recurrent block of the third degree and bradycardia. CONCLUSION: In saturation, ECG records lengthening of P-R intervals by 18.9%, on the average. Maintenance therapy increases the length of P-R interval by 8.1%, on the average.

Amiodarone↗
PubMed2005

[Dermatological adverse reactions of amiodarone].

Amiodarone, an iodine -- rich benzofurane derivate, is a highly effective agent for the prophylaxis and treatment of various cardiac arrhythmias, but it is associated with numerous side effects. Aim of this study was to elucidate dermatological adverse effects of therapy with amiodarone. Patients (n=468, mean age 48.7+/-0.7 years) receiving oral amiodarone were followed-up for 1-134 months (mean 20.85+/-1.2 months). Photosensitivity was quite common (41.4%). Spectrum of skin reactions was wide, ranging from erythema and swelling of area exposed to sunshine. Some patients (0.8%) developed pigmentation of the exposed skin areas.

Adolescent↗
PubMed2004

[Amiodarone (cordarone) efficiency in atrial extrasystole].

AIM: To assess antiarrhythmic amiodarone efficacy of suppressing atrial extrasystoles resistant to other antiarrhythmic modalities. MATERIAL AND METHODS: The antiarrhythmic effect of amiodarone was studied in 70 patients (38 males, 32 females, mean age 49.6 +/- 1.7 years, mean duration of arrhythmia 4.9 +/- 1.5 years). The loading oral dose of amiodarone was 600-1200 mg/day for 10 days, mean maintenance dose--1656.25 mg a week, mean duration of treatment--27.5 +/- 3.2 months. The response to amiodarone was estimated by repeated 24-h Holter monitoring. RESULTS: A complete response was observed in 78.5% patients in loading and in 65.7% patients in maintenance therapy. A partial antiarrhythmic response was seen in 8.57 and 16.41% patients, respectively. CONCLUSION: Amiodarone is a basic drug against ventricular arrhythmia. Its effectiveness in suppression of atrial extrasystole is weaker but also appropriate.

Adolescent↗
PubMed2004

[Hypomagnesemia in patients with chronic alcoholism in the course of alcohol withdrawal syndrome].

AIM: To ascertain hypomagnesemia (HM) rate in patients with chronic alcoholism (CA) with alcohol withdrawal syndrome (AWS); correlation between AWS severity and HM rate. MATERIAL AND METHODS: Mg in plasm was measured at photometry in 129 CA patients treated in Kaunas Mental Hospital. RESULTS: Plasma Mg in CA patients with AWS was reduced (< 0.749 mmol/l), normal (0.750-1.250 mmol/l) or high (> 1.251 mmol/l) in 28.7, 65.1 and 6.2% patients, respectively. HM was diagnosed in 42.3% with a severe, 19.1% with a moderate and 20.0% with weak AWS. CONCLUSION: HM in AWS was registered in 28.7% patients. It occurred significantly more frequently (p < 0.05) in patients with a severe AWS. Pathogenetic mechanisms of HM in AWS are described.

Adult↗
PubMed1978

[Prognosis in myocardial infarct complicated in the acute period by heart conduction disorders].

The influence of disorders of atrioventricular and intraventricular conduction, encountered in the acute period of myocardial infarction, on the immediate and remote prognosis of the disease was studied. In the acute period of myocardial infarction, III degree atrioventricular block and the right branch of the bundle of His block with the left posterior semiblock had a significant deteriorating effect on the prognosis. The remote prognosis was worse only due to the effect of III degree atrioventricular block.

Acute Disease↗
PubMed1976

[Jervell and Lange-Nielsen syndrome].

A rare case of the congenital cardiological syndrome of Jervell and Lange-Nielsen in a 6-year old boy is analyzed. A literature survey of the clinical picture, treatment of and prognosis in this and related to it the Romano-Ward syndrome is given.

Child↗
PubMedDate not supplied

[Examining the effect of amiodarone on the lung: prospective follow-up data].

Amiodarone (A) that belongs to Class III antiarrhythmics is a highly antiarrhythmic agents not only in treating, but in preventing various cardiac arrhythmias. However, its prolonged treatment may have an adverse life-threatening effect on the lung in 1-10% of patients. The purpose of our study was to verify the safe effect of A on the lung. Forty-one patients receiving A were examined in the period of its saturation and for the following 6 months. A hundred and forty-nine patients treated with its maintaining doses long (for 11 years) were also studied. Lung X-ray films and spirograms were repeated every 1-3 months at the beginning of therapy and then every 6 months. Side pulmonary effects were not observed. The findings may lead to the conclusion that comparatively small maintaining doses of A are safe for the patient.

Adolescent↗