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D Ia Shurygin

Publications and source records attributed to D Ia Shurygin.

42 records · Page 3Linked to original sources

[Changes in the indicators of hormonal activity of the adrenal glands, sympathetic-adrenal system and hemodynamics in healthy persons at different times during the 24-hour period].

The following were studied in 24 healthy men aged from 20 to 40 years: circadian rhythm of catecholamines and their precursors production, 17-ketosteroids, 17-oxycorticosteroids, variational pulsometry indices, arterial pressure parameters, resilient-viscous properties of large arterial vessels and arterioles, indices characterizing the mechanical activity of the myocardium. Comparison of the results obtained indicated that, although there existed no complete correlation between these indices, there proved to be a nocturnal tendency to reduction of noradrenaline and dopamine production, to reduction of 17-ketosteroids and 17-oxycorticosteroids, along with rarefaction of cardiac contractions, increased variation in the rhythm, and diminution of arterial pressure and cardiac output parameters. Reverse changes were noted during the day-time.

Adrenal Cortex↗

[Effect of different storage times of blood sera on their hormonal activity].

Hormonal activity of the sera was studied immediately after blood collection and 6 months, one year and 1.5 years following their storage at a temperature of -20 to 25 degrees C in 10 healthy males aged 18 to 20 years. It was found that differently directed changes in immunologic activity of blood serum hormones took place on long-term storage at low temperatures. The data obtained suggest that the adrenocorticotropic hormone, immunoreactive insulin, protein-bound iodine and follicle-stimulating hormone retain the immunologic activity not more than one year, while the hormone, stimulating interstitial cells, thyrotrophic hormone, somatotrophic hormone, 17-HOCS, testosterone and aldosterone up to 1-1.5 years. During this storage of frozen biosubstrates the recurrent freezing out that produces changes in the immunologic activity of some hormones should be excluded.

Adolescent↗