The nucleus isthmus as a relay station in the ipsilateral visual projection to the frog's optic tectum.
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Biomedical subjects
Publications and source records attributed to D Ingle.
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Goldfish with transections of the intertectal commissure learned but failed to transfer interocularly a simple visually cued avoidance task in a shuttle box, whereas posterior commissure lesions had no effect on this simple transfer task. However, fish with tectal commissure lesions could show normal interocular transfer of a shape discrimination, once discrimination pretraining with color cues had been carried out with each eye separately. Lesions of anterior commissure had no effect on either shape or color transfer, but fish with intended cuts of the postoptic commissures showed striking deficits of interocular transfer. As with comparable studies in the pigeon, it is concluded that postoptic, but not tectal, commissures are required for interocular transfer in the goldfish.
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The prey-catching response of frogs toward small moving objects can be facilitated by small movements of the same stimulus a few seconds earlier, even though initial movements seldom trigger the feeding response. This focal attention phenomenon may be related to the observation that one class of tectal unit continues to discharge for a few seconds following a brief stimulus motion. Together with anatomical data of other investigators, results of the present study suggest that self-exciting neural loops within the tectum mediate this type of selective attention.
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Gonorrhea case reports to the Alaska Department of Health and Social Services were used to study the contribution of reinfection to rates of gonorrhea infection in Alaska. The case reports of 13,910 infections among 11,132 persons who had laboratory-proven gonorrhea between 1983 and 1987 were examined. Among 1,886 persons who had multiple infections, the average number of infections per person was 2.5 (range = 2-11). These persons accounted for 33.5% of all infections and 16.9% of all patients with gonorrhea from 1983 to 1987. Compared to persons with one infection, those having multiple infections were more likely to be Alaska Natives (relative risk = 1.8, 95% confidence interval = 1.6-1.9) and less than 21 years of age (relative risk = 1.3, 95% confidence interval = 1.2-1.4). There was no difference in risk between men and women. Two thirds of the reinfections occurred within 12 months of the initial infection. If gonorrhea incidence were calculated based on the number of people infected rather than as a "case rate," the mean annual rate (per 100,000) from 1983 to 1987 decreased from 1,644 to 1,228 (a 25.3% decrease) for Alaska Natives and from 316 to 267 (a 15.5% decrease) for non-Natives. Reporting gonorrhea incidence rates by number of persons infected rather than by total number of cases more accurately measures gonorrhea morbidity in a population and will allow prevention efforts to be directed to those persons who contribute the most to perpetuating the disease.