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Biomedical subjects

D Iu Pushkar'

Publications and source records attributed to D Iu Pushkar'.

47 records · Page 3Linked to original sources
PubMedDate not supplied

[Premature ejaculation: diagnosis, classification, algorithm of the patients' examination and results of their application].

We have analysed literature data and own experience with management of premature ejaculation (PE) in 3200 patients. This gave grounds for formulation of this phenomenon, creation of the classification and the examination algorithm. We applied the proposed methods in the treatment of 258 PE patients and made the conclusion about their adequacy and efficacy. PE is a polyetiological phenomenon and a multidisciplinary problem. Urological examination must be used as the first stage of the diagnostic process.

Algorithms↗
PubMedDate not supplied

[Glandular squamous cell carcinoma of the urinary bladder].

The paper gives a clinical observation of a 52 year-old male with a rare histological urinary bladder tumor primary grandular-squamous-cell carcinoma (pT3N IM0). The tumor is represented by two components large acinic-cell adenocarcinoma and squamous-cell carcinoma with keratinization, which smoothly pass one into another; the tumor has grown through all layers of the urinary bladder wall but it has failed to grow into the peritoneum. A microscopic study has indicated that the urachus is intact. Metastases were found in 3 of 8 lymph nodes: one showed high-grade adenocarcinoma and two others displayed average-grade squamous-cell carcinoma.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

[A trial of the use of finasteride and terazosin in patients with benign prostatic hyperplasia].

94 patients with obstructive urination due to benign prostatic hyperplasia received finasteride (proscar), inhibitor of 5 alpha-reductase, in a single dose 5 mg and terazosine, alpha 1 adrenoblocker, in a daily dose of 9.7 mg/day. The follow-up averaged 16.1 months. As shown by overall score of the symptoms and quality of life, rectal and ultrasonic examinations, uroflowmetry, the prostate decreased by 17%, on the average in 72% of the patients. Subjectively, urination has also improved. Maximal flow rate elevated by 55% in the majority of patients. Combination of finasterine with terazosine is well tolerated and proved optimal as a conservative therapy in patients with obstructive urination as a result of benign prostatic hyperplasia.

5-alpha Reductase Inhibitors↗
PubMedDate not supplied

[Raz's operation in the treatment of stress urinary incontinence in women].

Postoperative recurrences of enuresis range from 8 to 51%. One of the ways to correct this disorder is modification of transcutaneous urethrocervicopexy, Raz operation, in particular. Raz operation was performed in 53 females, of them in 5 for recurrent enuresis. 4 patients underwent combined surgery: correction of anatomical defects of the bladder and urethra combined with Raz operation. Within 3-year follow-up a response was achieved in 48 (91%) patients. Negative outcomes are explained in females with high motility of the fundus of the urinary bladder as the above surgical procedure does not strengthen the support apparatus of the bladder.

Adult↗
PubMedDate not supplied

[The diagnostic value of combined urodynamic study in different forms of urinary incontinence in women].

Diagnostic potential of urodynamic tests was studied in 279 females with combined and complicated enuresis. 90 healthy females and 21 cadavers served control. The statistical analysis covered the following urodynamic parameters: cystometric volume, detrusor pressure in cystometric volume, functional urethral length, maximal intraurethral pressure, fluctuations of maximal intraurethral pressure. Isolated measurements of cystometric volume, functional urethral length and maximal intraurethral pressure failed to provide sufficient diagnostic information in effort enuresis, whereas cystometry was most efficient in diagnosis of detrusor instability. Registration of urethral pressure fluctuations in the maximal point allows detection of urethral instability. Combined urodynamic examination can not be fully rejected in patients with complicated and combined enuresis.

Adult↗
PubMedDate not supplied

[The surgical treatment of urinary stress incontinence in women by using a tube flap from the vagina].

According to statistical estimates, incidence of urinary stress incontinence (USI) in females ranges from 3 to 20%. Operative correction of USI is feasible by 200 methods. The authors propose one more procedure which implies cutting out of tube graft from the anterior vaginal wall followed by the graft fixation in the bladder cervical region and placing prolen supporting ligatures into the suprapubic area with a special needle. In 1992-1995 such operation was performed in 55 USI females with positive effect in 48 (89%) patients. The technique provides enhanced mobilization of the bladder posterior wall and paraurethral space performing plastic reconstruction of cystocele. Moreover, creation of vaginal tube graft in the zone of urethrovesical segment contributes to reconstruction of normal anatomy. Thus, sling operations are method of choice in the treatment of patients with type 3 USI.

Chronic Disease↗
PubMedDate not supplied

[Outpatient urodynamic monitoring in the diagnosis of subclinical forms of a urination disorder in women].

The authors studied potentialities of outpatient urodynamic monitoring in diagnosis of subclinical urination defects in females. The examination was made of 31 females aged 25-55 years (mean age 43.8 years) with complaints of pollakiuria, precipitant urination. Laboratory urodynamic investigation combined retrograde cystometry, profilometry and uroflowmetry (Jupiter 8000 Video produced by WIEST) and was followed by urodynamic monitoring (CAMSYS 6300 by WIEST). Standard combined urodynamic evaluation registered normal urodynamic parameters in 17 females, unstable urethra in 4, unstable detrusor in 7, unstable urethra and detrusor in 3 patients. The curves devised on the basis of the outpatient urodynamic monitoring data indicated that; normal urodynamics, unstable urethra, unstable detrusor, detrusor-sphincter dyssynergia, combined instability of urethra and detrusor, unstable detrusor plus detrusor-sphincter dyssynergia in 4, 10, 7, 3, 2, 2 females, respectively. 3 cases were ineligible. The above investigation promoted accurate diagnosis in 41.9% of cases. Outpatient monitoring is a method of choice in diagnosis of subclinical urination disorders.

Adult↗
PubMedDate not supplied

[Experience in the use of doxazosin in patients with benign hyperplasia of the prostate].

Selective alpha-1-adrenoblockers are thought promising in current conservative treatment of benign prostatic hyperplasia (BPH). The trial of doxazosin (cardura)--a selective alpha-blocker--included 78 BPH patients with obstructive urination. All the patients received a single daily dose of doxazosin 4-8 mg (mean 5.7 mg). 60 patients on placebo served as control. The comparison of the effects observed in the study vs control group has demonstrated that doxazosin has a favourable effect on BPH: it improved quality of life, relieved obstructive symptoms, reduced amount of residual urine. There is objective urodynamic evidence on decreased infravesical obstruction.

Adrenergic alpha-Antagonists↗