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Biomedical subjects

D Ivanković

Publications and source records attributed to D Ivanković.

At least 19 recordsLinked to original sources

[Respiratory symptoms and pulmonary ventilating capacity in professional drivers and mechanics].

The prevalence of respiratory symptoms and ventilatory capacity were studied in 116 drives and 119 mechanics. The drivers and mechanics demonstrated a significantly higher prevalence of most chronic respiratory symptoms than control workers. Among drivers smokers there was a significantly higher prevalence of most chronic respiratory symptoms than among non-smoking drivers. Drivers and mechanics with more than 10 years of service also showed a higher prevalence of respiratory symptoms than those employed for less than 10 years. A certain number of subjects complained of acute symptoms during work shift. All ventilatory capacity tests, particularly FEF25, demonstrated lower values in comparison to predicted normal values. Our data for drivers and mechanics indicate that long-term employment, particularly in combination with smoking, may cause the development of respiratory symptoms and changes in lung function.

Adult

Distribution of structural and trace elements in human temporal bone.

This study was undertaken to evaluate a systematic analysis of mineral and trace elements of individual functionally determined parts of adult temporal bone. Marked differences were observed in basic structural elements (Ca, P, Mg, and Zn) among different bone regions. The more so, molar Ca/P ratio was significantly different in various regions, being highest in the hammer and vestibular regions. Taxonomic analysis revealed specific differences in the mineral ratio between the two petrous bone regions believed to develop from various embryonal bases. According to results, the observed differences in mineral trace element composition of particular regions of human temporal bone might be explained by their developmental specificities and functional adaptation.

Adult

[Respiratory diseases, symptoms and ventilatory function in workers involved in processing food for livestock].

The prevalence of chronic and acute respiratory symptoms and ventilatory capacity were studied in a group of 71 workers employed in animal food processing. A control group of 55 unexposed workers was also included in the study. A significantly higher prevalence for most of the chronic respiratory symptoms was found among the exposed than among control workers. Exposed smokers had a significantly higher prevalence of chronic cough, chronic phlegm, chronic bronchitis and chest tightness than control smokers. The values for FVC, FEV1 and FEF50 measured in the exposed workers were significantly lower in comparison to predicted normal lung function values. In smokers all the measured parameters of ventilatory capacity were significantly lesser than predicted. For non-smokers only FVC and FEV1 were below normal. Our data indicate that occupational exposure to animal food may cause the development of acute and chronic respiratory symptoms and impairment of ventilatory capacity.

Adult

[Respiratory function in fur-processing workers].

Forty women employed as furriers in the fur processing industry and a group of 31 control workers were examined. A higher prevalence of chronic respiratory symptoms was found among the furriers than among the controls. The differences were statistically significant for chronic cough and sinusitis (P less than 0.01). The highest prevalence in furriers was found for chronic cough (50%), sinusitis (30%), followed by dyspnea (25%), nasal catarrh (20%) and occupational asthma (5%). A large number of workers complained of acute symptoms during work shift. Statistically significant mean acute reductions in ventilatory capacity over the workshift were recorded for FVC (-4.1%), FEV1 (-5.2%) and FEV50 (-6.3%). The furriers demonstrated significantly lower mean measured pre-shift values for FVC and FEV25 (P less than 0.05) when compared with the predicted. Pre-shift administration of 40 mg of Intal considerably diminished acute ventilatory capacity over the work shift.

Adult

[Varicosities of the lower extremities in workers in positions requiring continuous standing or sitting positions].

An epidemiological study of the prevalence of varicose veins of lower extremities was carried out in an industrial population of 434 men and 345 women. A statistically significant (p less than 0.05) association between the varicose disease and duration of work was found in all groups of workers, except for women sitting at work. Decrease in the prevalence of varicose veins after 20 years of employment may be explained at least partly, by the factor of self-selection in the industry. However, there was no difference in the prevalence of varicose veins between workers standing and those sitting at work.

Female

[Ventilatory function and allergic skin tests in cotton mill workers].

Ventilatory capacity, chronic respiratory symptoms and respiratory diseases as well as intradermal skin tests were registered in a group of 112 cotton workers. The prevalence of chronic respiratory symptoms and respiratory diseases was higher among the exposed than among control workers although the differences were statistically significant only for chronic cough, nasal catarrh and byssinosis in women and for chronic cough, chronic phlegm and byssinosis in men. A similar prevalence of byssinosis was noted in women (29.4%) and in men (29.5%). Among textile workers mostly byssinosis grade 1/2 was found (women 22.1%, men 20.5%). There were statistically significant acute reductions over work shift for forced vital capacity (FVC) and one-second forced expiratory volume (FEV1). In men the values were somewhat lower than the expected normal values. A very small number of workers demonstrated positive intradermal skin tests to cotton allergen (exposed 8.2%, control 1.8%). Our data indicate that exposure to cotton dust may lead to the development of respiratory symptoms and diseases as well as to acute changes in ventilatory capacity but without an allergic reaction.

Dust

Rapid detection of respiratory syncytial virus in clinical specimens.

Results of the direct immunofluorescence (IF) test in 152 clinical specimens (throat swabs) were compared with those of respiratory syncytial virus (RSV) isolation. The prevalence of RSV infections in the upper and lower respiratory tract was high especially in infants until 12 months of age. The average RSV isolation rate was 18.42%, whereas the virus antigen detection was positive in 19.74% of cases. The agreement between virus isolation and direct IF was 92.1%, the sensitivity of IF being 82.14% and its specificity 94.35%.

Adolescent

Immunological and respiratory changes in tea workers.

Immunological status and respiratory function were studied in 26 female nonsmokers employed in processing different types of tea. Skin tests with tea-allergens demonstrated the highest percentage of positive reaction to sage (45%), gruzyan (40%), mentha (35%), and dog rose (10%). Among 17 skin-tested control workers, 23% had positive skin reaction to sage, 19% to gruzyan tea, 20% to mentha and 11% to dog rose and Indian teas. Serum levels of total IgE were increased in 27% of the tea workers and in 7% of the control subjects. Prevalence of almost all chronic respiratory symptoms was higher in tea workers with positive skin tests than in those with negative skin tests to tea allergens. Tea workers with positive skin tests to tea allergens had larger mean acute reduction over the Monday workshift in flow rates (MEF50%: -11.9%; MEF25%: -20.6%) than in those with negative skin tests (MEF50%: -5.7%; MEF25%: -16.7%), thus suggesting an obstructive effect mostly located in smaller airways. Bronchoprovocation testing with different tea allergens provoked acute reductions of ventilatory capacity in four out of six subjects tested. Relative fall over a 90-min post exposure was greater in MEF25% (ranging from 13% to 67%) than in MEF 50% (ranging from 9% to 45% of the control values).

Adult

[Aequidensitometrie of the labyrinthic capsule with special regard of the bottom of the internal auditory meatus].

It has been proved by densitometry that the thickness of the separating wall between the basal coil and the fundus of the internal auditory meastus as well as the thickness of the labyrinthic wall increase with age. The mineral contents is simultaneously reduced. The diameter of the cochlear canal is also reduced with age. These facts have been demonstrated by aequidensitometry and by summation color pictures of aequidensites.

Adolescent

Further contribution in the densitometric study of the labyrinthic capsule with special reference to the bottom of the internal auditory meatus.

The quantity of minerals in the labyrinthic capsule of the basal coil and of the separating wall facing the internal auditory meatus in different life periods was determined by the densitometric method. The quantity of minerals is reduced in the labyrinthic capsule and in the separating wall in spite of the bone apposition and increasing thickness of the separating wall.

Adolescent